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Pupil diameter encodes the idiosyncratic, cognitive complexity of belief updating

Alexandre L.S. Filipowicz, Christopher M. Glaze, Joseph W. Kable, Joshua I. Gold
doi: https://doi.org/10.1101/736140
Alexandre L.S. Filipowicz
Department of Neursocience, University of PennsylvaniaDepartment of Psychology, University of PennsylvaniaDepartment of Computational Neuroscience Initiative, University of Pennsylvania
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  • For correspondence: alsfilip@pennmedicine.upenn.edu
Christopher M. Glaze
Department of Neursocience, University of PennsylvaniaDepartment of Psychology, University of PennsylvaniaDepartment of Computational Neuroscience Initiative, University of Pennsylvania
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Joseph W. Kable
Department of Psychology, University of PennsylvaniaDepartment of Computational Neuroscience Initiative, University of Pennsylvania
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Joshua I. Gold
Department of Neursocience, University of PennsylvaniaDepartment of Computational Neuroscience Initiative, University of Pennsylvania
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Abstract

Pupils tend to dilate in response to surprising events, but whether these responses are primarily stimulus driven or instead reflect a more nuanced relationship between pupil-linked arousal systems and cognitive expectations is not known. Using an auditory adaptive decision-making task, we show that evoked pupil diameter is modulated more strongly by violations of learned, top-down expectations than by changes in low-level stimulus properties. We further show that both baseline and evoked pupil diameter is modulated by the degree to which individual subjects use these violations to update their subsequent expectations, as reflected in the complexity of their updating strategy. Together these results demonstrate a central role for cognitive processing in how arousal systems respond to new inputs and, via our complexity-based analyses, provide a unified framework for understanding these effects in terms of both inference processes aimed to reduce belief uncertainty and more traditional notions of mental effort.

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  • ↵* co-first authors

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Posted August 22, 2019.
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Pupil diameter encodes the idiosyncratic, cognitive complexity of belief updating
Alexandre L.S. Filipowicz, Christopher M. Glaze, Joseph W. Kable, Joshua I. Gold
bioRxiv 736140; doi: https://doi.org/10.1101/736140
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Pupil diameter encodes the idiosyncratic, cognitive complexity of belief updating
Alexandre L.S. Filipowicz, Christopher M. Glaze, Joseph W. Kable, Joshua I. Gold
bioRxiv 736140; doi: https://doi.org/10.1101/736140

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