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Optimization of AsCas12a for combinatorial genetic screens in human cells
Kendall R Sanson, Peter C DeWeirdt, Annabel K Sangree, Ruth E Hanna, Mudra Hegde, Teng Teng, Samantha M Borys, Christine Strand, J Keith Joung, Benjamin P Kleinstiver, Xuewen Pan, Alan Huang, View ORCID ProfileJohn G Doench
doi: https://doi.org/10.1101/747170
Kendall R Sanson
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Peter C DeWeirdt
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Annabel K Sangree
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Ruth E Hanna
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Mudra Hegde
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Teng Teng
2Tango Therapeutics, 100 Binney St., Cambridge, MA
Samantha M Borys
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Christine Strand
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
J Keith Joung
3Molecular Pathology Unit, Massachusetts General Hospital, Charlestown, MA, USA
4Center for Cancer Research, Massachusetts General Hospital, Charlestown, MA, USA
5Center for Computational and Integrative Biology, Massachusetts General Hospital, Charlestown, MA, USA
6Department of Pathology, Harvard Medical School, Boston, MA, USA
Benjamin P Kleinstiver
6Department of Pathology, Harvard Medical School, Boston, MA, USA
7Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA 02114
8Department of Pathology, Massachusetts General Hospital, Boston, MA 02114
Xuewen Pan
2Tango Therapeutics, 100 Binney St., Cambridge, MA
Alan Huang
2Tango Therapeutics, 100 Binney St., Cambridge, MA
John G Doench
1Genetic Perturbation Platform, Broad Institute of MIT and Harvard, Cambridge, MA, USA
Article usage
Posted August 28, 2019.
Optimization of AsCas12a for combinatorial genetic screens in human cells
Kendall R Sanson, Peter C DeWeirdt, Annabel K Sangree, Ruth E Hanna, Mudra Hegde, Teng Teng, Samantha M Borys, Christine Strand, J Keith Joung, Benjamin P Kleinstiver, Xuewen Pan, Alan Huang, John G Doench
bioRxiv 747170; doi: https://doi.org/10.1101/747170
Optimization of AsCas12a for combinatorial genetic screens in human cells
Kendall R Sanson, Peter C DeWeirdt, Annabel K Sangree, Ruth E Hanna, Mudra Hegde, Teng Teng, Samantha M Borys, Christine Strand, J Keith Joung, Benjamin P Kleinstiver, Xuewen Pan, Alan Huang, John G Doench
bioRxiv 747170; doi: https://doi.org/10.1101/747170
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