Abstract
MicroRNAs (miRNAs) are major regulators of gene expression in multicellular organisms. Many of the evolutionarily conserved miRNAs in plants are encoded by small gene families. The miR159/miR319 family has six members of similar sequences sharing 17 nucleotides in Arabidopsis thaliana. The members of this miRNA family regulate genes encoding TCP (TEOSINTE BRANCHED1, CYCLOIDEA and PCF1/2) and MYB transcription factors. However, despite their sequence similarities, genetic evidence indicates that miR159 and miR319 fulfil different roles in vivo. Here, we confirm previous findings showing that TCP genes are not targeted by miR159. Thus, specific small sequence differences between the miRNAs allow for the specific regulation of TCP transcription factors by miR319 miRNAs.
Footnotes
Detlef Weigel weigel{at}weigelworld.org
