Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Neuromodulation and Differential Learning Across Mosquito Species

View ORCID ProfileGabriella H. Wolff, View ORCID ProfileChloé Lahondère, View ORCID ProfileClément Vinauger, View ORCID ProfileJeffrey A. Riffell
doi: https://doi.org/10.1101/755017
Gabriella H. Wolff
1Department of Biology, University of Washington, Seattle, WA 98195-7270, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Gabriella H. Wolff
Chloé Lahondère
1Department of Biology, University of Washington, Seattle, WA 98195-7270, USA
2Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Chloé Lahondère
Clément Vinauger
1Department of Biology, University of Washington, Seattle, WA 98195-7270, USA
2Department of Biochemistry, Virginia Tech, Blacksburg, VA 24061, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Clément Vinauger
Jeffrey A. Riffell
1Department of Biology, University of Washington, Seattle, WA 98195-7270, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jeffrey A. Riffell
  • For correspondence: jriffell@uw.edu
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Preview PDF
Loading

Abstract

Mosquitoes can learn to change their host-feeding behaviors, such as shifting activity times to avoid bednets or switching from biting animals to biting humans, leading to the transfer of zoonotic diseases. Dopamine is critical for insect learning, but its role in the antennal lobe remains unclear, and it is unknown whether different mosquito species learn the same odor cues. We assayed aversive olfactory learning and dopaminergic brain innervation in four mosquito species with different host preferences and report here that they differentially learn odors salient to their preferred host and innervation patterns vary across species. Using genetically-encoded GCaMP6s Aedes aegypti, we mapped odor-evoked antennal lobe activity and report that glomeruli tuned to “learnable” odors have significantly higher dopaminergic innervation. Changes in dopamine expression in the antennal lobes of diverse invertebrate species may be an evolutionary mechanism to adapt olfactory learning circuitry without changing brain structure and for mosquitoes an ability to adapt to other hosts when their preferred are no longer present.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted September 05, 2019.
Download PDF
Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Neuromodulation and Differential Learning Across Mosquito Species
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Neuromodulation and Differential Learning Across Mosquito Species
Gabriella H. Wolff, Chloé Lahondère, Clément Vinauger, Jeffrey A. Riffell
bioRxiv 755017; doi: https://doi.org/10.1101/755017
Digg logo Reddit logo Twitter logo Facebook logo Google logo LinkedIn logo Mendeley logo
Citation Tools
Neuromodulation and Differential Learning Across Mosquito Species
Gabriella H. Wolff, Chloé Lahondère, Clément Vinauger, Jeffrey A. Riffell
bioRxiv 755017; doi: https://doi.org/10.1101/755017

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Neuroscience
Subject Areas
All Articles
  • Animal Behavior and Cognition (3498)
  • Biochemistry (7342)
  • Bioengineering (5318)
  • Bioinformatics (20249)
  • Biophysics (10000)
  • Cancer Biology (7735)
  • Cell Biology (11292)
  • Clinical Trials (138)
  • Developmental Biology (6431)
  • Ecology (9943)
  • Epidemiology (2065)
  • Evolutionary Biology (13312)
  • Genetics (9358)
  • Genomics (12575)
  • Immunology (7696)
  • Microbiology (18999)
  • Molecular Biology (7432)
  • Neuroscience (40976)
  • Paleontology (300)
  • Pathology (1228)
  • Pharmacology and Toxicology (2133)
  • Physiology (3155)
  • Plant Biology (6857)
  • Scientific Communication and Education (1272)
  • Synthetic Biology (1895)
  • Systems Biology (5310)
  • Zoology (1087)