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Maternal exposure to a mitochondrial toxicant results in life-long alterations in DNA methylation and gene expression in the offspring

View ORCID ProfileOswaldo A. Lozoya, Fuhua Xu, Dagoberto Grenet, Tianyuan Wang, Sara A. Grimm, Veronica G. Godfrey, Suramya Waidyanatha, Richard P. Woychik, Janine H. Santos
doi: https://doi.org/10.1101/758474
Oswaldo A. Lozoya
Genome Integrity and Structural Biology Laboratory, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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  • ORCID record for Oswaldo A. Lozoya
Fuhua Xu
Genome Integrity and Structural Biology Laboratory, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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Dagoberto Grenet
Genome Integrity and Structural Biology Laboratory, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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Tianyuan Wang
Integrative Bioinformatics Support Group, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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Sara A. Grimm
Integrative Bioinformatics Support Group, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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Veronica G. Godfrey
National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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Suramya Waidyanatha
National Toxicology Program, National Institute of Environmental Health Sciences, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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Richard P. Woychik
Genome Integrity and Structural Biology Laboratory, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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  • For correspondence: janine.santos@nih.gov rick.woychik@nih.gov
Janine H. Santos
Genome Integrity and Structural Biology Laboratory, National Institutes of Health, 111 TW Alexander Drive, Research Triangle Park, NC, 27709
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  • For correspondence: janine.santos@nih.gov rick.woychik@nih.gov
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Article usage: September 2019 to December 2019

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Posted September 10, 2019.
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Maternal exposure to a mitochondrial toxicant results in life-long alterations in DNA methylation and gene expression in the offspring
Oswaldo A. Lozoya, Fuhua Xu, Dagoberto Grenet, Tianyuan Wang, Sara A. Grimm, Veronica G. Godfrey, Suramya Waidyanatha, Richard P. Woychik, Janine H. Santos
bioRxiv 758474; doi: https://doi.org/10.1101/758474
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Maternal exposure to a mitochondrial toxicant results in life-long alterations in DNA methylation and gene expression in the offspring
Oswaldo A. Lozoya, Fuhua Xu, Dagoberto Grenet, Tianyuan Wang, Sara A. Grimm, Veronica G. Godfrey, Suramya Waidyanatha, Richard P. Woychik, Janine H. Santos
bioRxiv 758474; doi: https://doi.org/10.1101/758474

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