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Most cancers carry a substantial deleterious load due to Hill-Robertson interference

View ORCID ProfileSusanne Tilk, View ORCID ProfileChristina Curtis, View ORCID ProfileDmitri A Petrov, View ORCID ProfileChristopher D McFarland
doi: https://doi.org/10.1101/764340
Susanne Tilk
1Department of Biology, Stanford University, Stanford CA 94305
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Christina Curtis
2Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA
3Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA
4Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA
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Dmitri A Petrov
1Department of Biology, Stanford University, Stanford CA 94305
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Christopher D McFarland
1Department of Biology, Stanford University, Stanford CA 94305
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  • For correspondence: cmcfarl2@stanford.edu
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Article Information

doi 
https://doi.org/10.1101/764340
History 
  • February 24, 2021.

Article Versions

  • Version 1 (September 14, 2019 - 00:56).
  • Version 2 (September 16, 2019 - 13:08).
  • Version 3 (August 23, 2020 - 21:55).
  • You are viewing Version 4, the most recent version of this article.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Susanne Tilk1,
  2. Christina Curtis2,3,4,
  3. Dmitri A Petrov1,* and
  4. Christopher D McFarland1,†
  1. 1Department of Biology, Stanford University, Stanford CA 94305
  2. 2Department of Medicine, Division of Oncology, Stanford University School of Medicine, Stanford, CA, USA
  3. 3Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA
  4. 4Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA, USA
  1. ↵† Corresponding author; email: cmcfarl2{at}stanford.edu
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Posted February 24, 2021.
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Most cancers carry a substantial deleterious load due to Hill-Robertson interference
Susanne Tilk, Christina Curtis, Dmitri A Petrov, Christopher D McFarland
bioRxiv 764340; doi: https://doi.org/10.1101/764340
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Most cancers carry a substantial deleterious load due to Hill-Robertson interference
Susanne Tilk, Christina Curtis, Dmitri A Petrov, Christopher D McFarland
bioRxiv 764340; doi: https://doi.org/10.1101/764340

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