Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Roser Vilarrasa-Blasi; Paula Soler-Vila; Núria Verdaguer-Dot; Núria Russiñol; Marco Di Stefano; Vicente Chapaprieta; Guillem Clot; Irene Farabella; Pol Cuscó; Xabier Agirre; Felipe Prosper; Renée Beekman; Silvia Beà; Dolors Colomer; Henk Stunnenberg; Ivo Gut; Elias Campo; Marc A. Marti-Renom; José Ignacio Martin-Subero

doi:10.1101/764910

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Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Roser Vilarrasa-Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Xabier Agirre, Felipe Prosper, Renée Beekman, Silvia Beà, Dolors Colomer, Henk Stunnenberg, View ORCID ProfileIvo Gut, Elias Campo, Marc A. Marti-Renom, José Ignacio Martin-Subero

doi: https://doi.org/10.1101/764910

Roser Vilarrasa-Blasi

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

2Departament de Fonaments Clínics, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain

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Paula Soler-Vila

3CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

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Núria Verdaguer-Dot

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

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Núria Russiñol

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

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Marco Di Stefano

3CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

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Vicente Chapaprieta

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

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Guillem Clot

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

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Irene Farabella

3CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

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Pol Cuscó

4Gastrointestinal and Endocrine Tumors Group, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain

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Xabier Agirre

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

6Área de Oncología, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigación Sanitaria de Navarra (IdiSNA), Universidad de Navarra, Pamplona, Spain

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Felipe Prosper

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

6Área de Oncología, Centro de Investigación Médica Aplicada (CIMA), Instituto de Investigación Sanitaria de Navarra (IdiSNA), Universidad de Navarra, Pamplona, Spain

7Departamento de Hematología, Clínica Universidad de Navarra, Universidad de Navarra, Pamplona, Spain

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Renée Beekman

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

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Silvia Beà

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

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Dolors Colomer

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

8Hematopathology Section, Hospital Clinic of Barcelona, Barcelona, Spain

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Henk Stunnenberg

9Molecular Biology, NCMLS, FNWI, Radboud University, Nijmegen, The Netherlands

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Ivo Gut

3CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

10Universitat Pompeu Fabra (UPF), Barcelona, Spain

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ORCID record for Ivo Gut

Elias Campo

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

2Departament de Fonaments Clínics, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

11Fundació Clínic per a la Recerca Biomèdica, Barcelona, Spain

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Marc A. Marti-Renom

3CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

10Universitat Pompeu Fabra (UPF), Barcelona, Spain

12ICREA, Barcelona, Spain

13Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain

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José Ignacio Martin-Subero

1Institut d’lnvestigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain

2Departament de Fonaments Clínics, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain

5Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain

12ICREA, Barcelona, Spain

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For correspondence: imartins@clinic.cat martirenom@cnag.crg.eu

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Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Roser Vilarrasa-Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Xabier Agirre, Felipe Prosper, Renée Beekman, Silvia Beà, Dolors Colomer, Henk Stunnenberg, Ivo Gut, Elias Campo, Marc A. Marti-Renom, José Ignacio Martin-Subero

bioRxiv 764910; doi: https://doi.org/10.1101/764910

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Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation

Roser Vilarrasa-Blasi, Paula Soler-Vila, Núria Verdaguer-Dot, Núria Russiñol, Marco Di Stefano, Vicente Chapaprieta, Guillem Clot, Irene Farabella, Pol Cuscó, Xabier Agirre, Felipe Prosper, Renée Beekman, Silvia Beà, Dolors Colomer, Henk Stunnenberg, Ivo Gut, Elias Campo, Marc A. Marti-Renom, José Ignacio Martin-Subero

bioRxiv 764910; doi: https://doi.org/10.1101/764910

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