New Results
Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomics
View ORCID ProfileP Ramachandran, R Dobie, JR Wilson-Kanamori, EF Dora, BEP Henderson, RS Taylor, KP Matchett, JR Portman, M Efremova, R Vento-Tormo, NT Luu, View ORCID ProfileCJ Weston, PN Newsome, View ORCID ProfileEM Harrison, View ORCID ProfileDJ Mole, SJ Wigmore, JP Iredale, F Tacke, JW Pollard, View ORCID ProfileCP Ponting, JC Marioni, SA Teichmann, View ORCID ProfileNC Henderson
doi: https://doi.org/10.1101/766113
P Ramachandran
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
R Dobie
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
JR Wilson-Kanamori
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
EF Dora
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
BEP Henderson
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
RS Taylor
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
KP Matchett
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
JR Portman
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
M Efremova
2Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK
R Vento-Tormo
2Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK
NT Luu
3National Institute for Health Research Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute for Immunology and Immunotherapy (III), Institute for Biomedical Research, University of Birmingham, Birmingham, UK
CJ Weston
3National Institute for Health Research Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute for Immunology and Immunotherapy (III), Institute for Biomedical Research, University of Birmingham, Birmingham, UK
PN Newsome
3National Institute for Health Research Biomedical Research Unit and Centre for Liver and Gastrointestinal Research, Institute for Immunology and Immunotherapy (III), Institute for Biomedical Research, University of Birmingham, Birmingham, UK
EM Harrison
4Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK
DJ Mole
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
4Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK
SJ Wigmore
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
4Clinical Surgery, University of Edinburgh, Royal Infirmary of Edinburgh, Edinburgh, UK
JP Iredale
5Senate House, University of Bristol, Bristol, UK
F Tacke
6Department of Hepatology and Gastroenterology, Charité University Medical Center, Berlin, Germany
JW Pollard
7MRC Centre for Reproductive Health, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
8Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, New York, USA
CP Ponting
9MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine at the University of Edinburgh, Edinburgh, UK
JC Marioni
2Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK
10European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridge, UK
11Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK
SA Teichmann
2Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK
11Cancer Research UK Cambridge Institute, University of Cambridge, Li Ka Shing Centre, Cambridge, UK
12Theory of Condensed Matter Group, The Cavendish Laboratory, University of Cambridge, JJ Thomas Ave, Cambridge, CD3 0EH, UK
NC Henderson
1Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh, UK
Article usage
Posted September 12, 2019.
Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomics
P Ramachandran, R Dobie, JR Wilson-Kanamori, EF Dora, BEP Henderson, RS Taylor, KP Matchett, JR Portman, M Efremova, R Vento-Tormo, NT Luu, CJ Weston, PN Newsome, EM Harrison, DJ Mole, SJ Wigmore, JP Iredale, F Tacke, JW Pollard, CP Ponting, JC Marioni, SA Teichmann, NC Henderson
bioRxiv 766113; doi: https://doi.org/10.1101/766113
Resolving the fibrotic niche of human liver cirrhosis using single-cell transcriptomics
P Ramachandran, R Dobie, JR Wilson-Kanamori, EF Dora, BEP Henderson, RS Taylor, KP Matchett, JR Portman, M Efremova, R Vento-Tormo, NT Luu, CJ Weston, PN Newsome, EM Harrison, DJ Mole, SJ Wigmore, JP Iredale, F Tacke, JW Pollard, CP Ponting, JC Marioni, SA Teichmann, NC Henderson
bioRxiv 766113; doi: https://doi.org/10.1101/766113
Subject Area
Subject Areas
- Biochemistry (11755)
- Bioengineering (8757)
- Bioinformatics (29209)
- Biophysics (14980)
- Cancer Biology (12103)
- Cell Biology (17416)
- Clinical Trials (138)
- Developmental Biology (9425)
- Ecology (14187)
- Epidemiology (2067)
- Evolutionary Biology (18314)
- Genetics (12246)
- Genomics (16807)
- Immunology (11870)
- Microbiology (28101)
- Molecular Biology (11599)
- Neuroscience (60995)
- Paleontology (452)
- Pathology (1872)
- Pharmacology and Toxicology (3238)
- Physiology (4961)
- Plant Biology (10429)
- Synthetic Biology (2887)
- Systems Biology (7341)
- Zoology (1651)