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Genetic drug target validation using Mendelian randomization
View ORCID ProfileA F Schmidt, C Finan, M Gordillo-Marañón, View ORCID ProfileF W Asselbergs, D F Freitag, R S Patel, B Tyl, S Chopade, R Faraway, M Zwierzyna, A D Hingorani
doi: https://doi.org/10.1101/781039
A F Schmidt
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
cDepartment of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands
C Finan
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
M Gordillo-Marañón
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
F W Asselbergs
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
cDepartment of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands
D F Freitag
dBayer AG Open Innovation & Digital Technologies, Pharmaceuticals, Wuppertal 42096, Germany
R S Patel
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
B Tyl
eCardiovascular Center for Therapeutic Innovation, Institut de Recherches Internationales Servier, Suresnes, France
S Chopade
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
R Faraway
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
M Zwierzyna
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
fBenevolent AI, London W1T 5HD, United Kingdom
A D Hingorani
aInstitute of Cardiovascular Science, Faculty of Population Health, University College London, London WC1E 6BT, United Kingdom
bUCL’s BHF Research Accelerator centre.
Article usage
Posted September 25, 2019.
Genetic drug target validation using Mendelian randomization
A F Schmidt, C Finan, M Gordillo-Marañón, F W Asselbergs, D F Freitag, R S Patel, B Tyl, S Chopade, R Faraway, M Zwierzyna, A D Hingorani
bioRxiv 781039; doi: https://doi.org/10.1101/781039
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