Sensitivity to gains during risky decision-making differentiates chronic cocaine users from stimulant-naïve controls

B. Kluwe-Schiavon; A. Kexel; G. Manenti; D.M. Cole; M.R. Baumgartner; R. Grassi-Oliveira; P.N. Tobler; B.B. Quednow

doi:10.1101/795443

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Sensitivity to gains during risky decision-making differentiates chronic cocaine users from stimulant-naïve controls

B. Kluwe-Schiavon, A. Kexel, G. Manenti, D.M. Cole, M.R. Baumgartner, R. Grassi-Oliveira, P.N. Tobler, B.B. Quednow

doi: https://doi.org/10.1101/795443

B. Kluwe-Schiavon

Experimental and Clinical Pharmacopsychology; Department of Psychiatry, Psychotherapy, and Psychosomatics; Psychiatric Hospital, University of Zurich; Switzerland

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For correspondence: bruno.kluwe@bli.uzh.ch

A. Kexel

Experimental and Clinical Pharmacopsychology; Department of Psychiatry, Psychotherapy, and Psychosomatics; Psychiatric Hospital, University of Zurich; Switzerland

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G. Manenti

Experimental and Clinical Pharmacopsychology; Department of Psychiatry, Psychotherapy, and Psychosomatics; Psychiatric Hospital, University of Zurich; SwitzerlandNeural Circuits and Cognition Lab, European Neuroscience Institute Göttingen, University Medical Center Göttingen and Max-Planck-Society, Germany

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D.M. Cole

Experimental and Clinical Pharmacopsychology; Department of Psychiatry, Psychotherapy, and Psychosomatics; Psychiatric Hospital, University of Zurich; Switzerland

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M.R. Baumgartner

Center of Forensic Hairanalytics, Institute of Forensic Medicine, University of Zurich, Switzerland

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R. Grassi-Oliveira

Developmental Cognitive Neuroscience Laboratory; Brain Institute; Pontifical Catholic University of Rio Grande do Sul; Brazil

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P.N. Tobler

Zurich Center for Neuroeconomics, Department of Economics, University of Zürich, SwitzerlandNeuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Switzerland

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B.B. Quednow

Experimental and Clinical Pharmacopsychology; Department of Psychiatry, Psychotherapy, and Psychosomatics; Psychiatric Hospital, University of Zurich; SwitzerlandNeuroscience Center Zurich, University of Zurich and Swiss Federal Institute of Technology Zurich, Switzerland