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An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cells
View ORCID ProfileSarah Bowling, View ORCID ProfileDuluxan Sritharan, View ORCID ProfileFernando G. Osorio, View ORCID ProfileMaximilian Nguyen, Priscilla Cheung, View ORCID ProfileAlejo Rodriguez-Fraticelli, Sachin Patel, View ORCID ProfileYuko Fujiwara, Bin E. Li, View ORCID ProfileStuart H. Orkin, View ORCID ProfileSahand Hormoz, Fernando D. Camargo
doi: https://doi.org/10.1101/797597
Sarah Bowling
1Stem Cell Program, Boston Children’s Hospital, Boston, MA, USA
2Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Duluxan Sritharan
3Harvard Graduate Program in Biophysics, Harvard University, Cambridge, MA, USA
4Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
Fernando G. Osorio
1Stem Cell Program, Boston Children’s Hospital, Boston, MA, USA
2Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Maximilian Nguyen
4Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
5Department of Systems Biology, Harvard Medical School, Boston, MA, USA
Priscilla Cheung
1Stem Cell Program, Boston Children’s Hospital, Boston, MA, USA
2Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Alejo Rodriguez-Fraticelli
1Stem Cell Program, Boston Children’s Hospital, Boston, MA, USA
2Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Sachin Patel
1Stem Cell Program, Boston Children’s Hospital, Boston, MA, USA
2Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Yuko Fujiwara
6Division of Hematology/Oncology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA
Bin E. Li
6Division of Hematology/Oncology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA
7Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA
Stuart H. Orkin
6Division of Hematology/Oncology, Boston Children’s Hospital, Harvard Medical School, Boston, MA, USA
8Howard Hughes Medical Institute, Boston, MA, USA
Sahand Hormoz
4Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA, USA
5Department of Systems Biology, Harvard Medical School, Boston, MA, USA
9Broad Institute of MIT and Harvard, Cambridge, MA, USA
Fernando D. Camargo
1Stem Cell Program, Boston Children’s Hospital, Boston, MA, USA
2Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA
Posted October 17, 2019.
An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cells
Sarah Bowling, Duluxan Sritharan, Fernando G. Osorio, Maximilian Nguyen, Priscilla Cheung, Alejo Rodriguez-Fraticelli, Sachin Patel, Yuko Fujiwara, Bin E. Li, Stuart H. Orkin, Sahand Hormoz, Fernando D. Camargo
bioRxiv 797597; doi: https://doi.org/10.1101/797597
An engineered CRISPR/Cas9 mouse line for simultaneous readout of lineage histories and gene expression profiles in single cells
Sarah Bowling, Duluxan Sritharan, Fernando G. Osorio, Maximilian Nguyen, Priscilla Cheung, Alejo Rodriguez-Fraticelli, Sachin Patel, Yuko Fujiwara, Bin E. Li, Stuart H. Orkin, Sahand Hormoz, Fernando D. Camargo
bioRxiv 797597; doi: https://doi.org/10.1101/797597
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