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Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4
Amandeep Girdhar, Vidhya Bharathi, Vikas Ramyagya Tiwari, Suman Abhishek, Usha Saraswat Mahawar, Gembali Raju, Sandeep Kumar Singh, Ganesan Prabusankar, Eerappa Rajakumara, View ORCID ProfileBasant K Patel
doi: https://doi.org/10.1101/797613
Amandeep Girdhar
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
Vidhya Bharathi
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
Vikas Ramyagya Tiwari
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
2National Centre for Biological Sciences, Bengaluru, Karnataka, India
Suman Abhishek
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
Usha Saraswat Mahawar
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
3Virginia Commonwealth University, Richmond, USA
Gembali Raju
4Department of Chemistry, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
Sandeep Kumar Singh
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
Ganesan Prabusankar
4Department of Chemistry, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
Eerappa Rajakumara
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
Basant K Patel
1Department of Biotechnology, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana-502285, India
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Posted October 08, 2019.
Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4
Amandeep Girdhar, Vidhya Bharathi, Vikas Ramyagya Tiwari, Suman Abhishek, Usha Saraswat Mahawar, Gembali Raju, Sandeep Kumar Singh, Ganesan Prabusankar, Eerappa Rajakumara, Basant K Patel
bioRxiv 797613; doi: https://doi.org/10.1101/797613
Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4
Amandeep Girdhar, Vidhya Bharathi, Vikas Ramyagya Tiwari, Suman Abhishek, Usha Saraswat Mahawar, Gembali Raju, Sandeep Kumar Singh, Ganesan Prabusankar, Eerappa Rajakumara, Basant K Patel
bioRxiv 797613; doi: https://doi.org/10.1101/797613
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