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CCmed: cross-condition mediation analysis for identifying robust trans-eQTLs and assessing their effects on human traits

Fan Yang, Kevin J. Gleason, Jiebiao Wang, The GTEx consortium, Jubao Duan, Xin He, Brandon L Pierce, Lin S Chen
doi: https://doi.org/10.1101/803106
Fan Yang
1Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, 13001 E. 17th Place, Aurora, Colorado 80045.
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Kevin J. Gleason
2Department of Public Health Sciences, University of Chicago, 5841 South Maryland Ave MC2000, Chicago, IL 60637.
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Jiebiao Wang
3Department of Statistics and Data Science, Carnegie Mellon University, Baker Hall, Carnegie Mellon University, Pittsburgh, PA 15213.
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Jubao Duan
4Center for Psychiatric Genetics, NorthShore University HealthSystem, 1001 University Place, Evanston, IL 60201.
5Department of Psychiatry and Behavioral Neuroscience, 5841 S Maryland Ave, Chicago MC3077, Chicago, IL 60637.
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Xin He
6Department of Human Genetics, University of Chicago, 920 E 58th St, Chicago, IL 60637.
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Brandon L Pierce
1Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, 13001 E. 17th Place, Aurora, Colorado 80045.
6Department of Human Genetics, University of Chicago, 920 E 58th St, Chicago, IL 60637.
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Lin S Chen
2Department of Public Health Sciences, University of Chicago, 5841 South Maryland Ave MC2000, Chicago, IL 60637.
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  • For correspondence: lchen@health.bsd.uchicago.edu
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Article Information

doi 
https://doi.org/10.1101/803106
History 
  • October 13, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Fan Yang1,†,
  2. Kevin J. Gleason2,†,
  3. Jiebiao Wang3,
  4. The GTEx consortium,
  5. Jubao Duan4,5,
  6. Xin He6,
  7. Brandon L Pierce1,6 and
  8. Lin S Chen2,*
  1. 1Department of Biostatistics and Informatics, Colorado School of Public Health, University of Colorado Denver, 13001 E. 17th Place, Aurora, Colorado 80045.
  2. 2Department of Public Health Sciences, University of Chicago, 5841 South Maryland Ave MC2000, Chicago, IL 60637.
  3. 3Department of Statistics and Data Science, Carnegie Mellon University, Baker Hall, Carnegie Mellon University, Pittsburgh, PA 15213.
  4. 4Center for Psychiatric Genetics, NorthShore University HealthSystem, 1001 University Place, Evanston, IL 60201.
  5. 5Department of Psychiatry and Behavioral Neuroscience, 5841 S Maryland Ave, Chicago MC3077, Chicago, IL 60637.
  6. 6Department of Human Genetics, University of Chicago, 920 E 58th St, Chicago, IL 60637.
  1. ↵*Correspondence: lchen{at}health.bsd.uchicago.edu
  1. ↵† Equal contributor

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CCmed: cross-condition mediation analysis for identifying robust trans-eQTLs and assessing their effects on human traits
Fan Yang, Kevin J. Gleason, Jiebiao Wang, The GTEx consortium, Jubao Duan, Xin He, Brandon L Pierce, Lin S Chen
bioRxiv 803106; doi: https://doi.org/10.1101/803106
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CCmed: cross-condition mediation analysis for identifying robust trans-eQTLs and assessing their effects on human traits
Fan Yang, Kevin J. Gleason, Jiebiao Wang, The GTEx consortium, Jubao Duan, Xin He, Brandon L Pierce, Lin S Chen
bioRxiv 803106; doi: https://doi.org/10.1101/803106

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