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Encephalitic alphaviruses exploit caveolae-mediated transcytosis at the blood-brain barrier for CNS entry

Hamid Salimi, Matthew D. Cain, Xiaoping Jiang, Robyn A. Roth, Wandy Beatty, Chengqun Sun, William B. Klimstra, Jianghui Hou, Robyn S. Klein
doi: https://doi.org/10.1101/805945
Hamid Salimi
1Department of Medicine, Washington University School of Medicine, St. Louis, MO
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Matthew D. Cain
1Department of Medicine, Washington University School of Medicine, St. Louis, MO
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Xiaoping Jiang
1Department of Medicine, Washington University School of Medicine, St. Louis, MO
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Robyn A. Roth
1Department of Medicine, Washington University School of Medicine, St. Louis, MO
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Wandy Beatty
1Department of Medicine, Washington University School of Medicine, St. Louis, MO
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Chengqun Sun
2Department of Immunology and Center for Vaccine Research2, University of Pittsburgh, Pittsburgh, PA
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William B. Klimstra
2Department of Immunology and Center for Vaccine Research2, University of Pittsburgh, Pittsburgh, PA
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Jianghui Hou
1Department of Medicine, Washington University School of Medicine, St. Louis, MO
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Robyn S. Klein
1Department of Medicine, Washington University School of Medicine, St. Louis, MO
3Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
4Department of Neuroscience, Washington University School of Medicine, St. Louis, MO
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  • For correspondence: rklein@wustl.edu
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Article Information

doi 
https://doi.org/10.1101/805945
History 
  • October 16, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.

Author Information

  1. Hamid Salimi1,
  2. Matthew D. Cain1,
  3. Xiaoping Jiang1,
  4. Robyn A. Roth1,
  5. Wandy Beatty1,
  6. Chengqun Sun2,
  7. William B. Klimstra2,
  8. Jianghui Hou1 and
  9. Robyn S. Klein1,3,4,*
  1. 1Department of Medicine, Washington University School of Medicine, St. Louis, MO
  2. 2Department of Immunology and Center for Vaccine Research2, University of Pittsburgh, Pittsburgh, PA
  3. 3Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO
  4. 4Department of Neuroscience, Washington University School of Medicine, St. Louis, MO
  1. ↵*Correspondence should be addressed to R.S.K. (rklein{at}wustl.edu). Robyn S. Klein, M.D., Ph.D., Washington University School of Medicine, Departments of Internal Medicine, Neurobiology, Pathology & Immunology, Campus Box 8051, 660 S. Euclid Ave, St. Louis, MO 63110, Phone: (314) 286-2140, Fax: (314) 362-9230, rklein{at}wustl.edu
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Posted October 16, 2019.
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Encephalitic alphaviruses exploit caveolae-mediated transcytosis at the blood-brain barrier for CNS entry
Hamid Salimi, Matthew D. Cain, Xiaoping Jiang, Robyn A. Roth, Wandy Beatty, Chengqun Sun, William B. Klimstra, Jianghui Hou, Robyn S. Klein
bioRxiv 805945; doi: https://doi.org/10.1101/805945
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Encephalitic alphaviruses exploit caveolae-mediated transcytosis at the blood-brain barrier for CNS entry
Hamid Salimi, Matthew D. Cain, Xiaoping Jiang, Robyn A. Roth, Wandy Beatty, Chengqun Sun, William B. Klimstra, Jianghui Hou, Robyn S. Klein
bioRxiv 805945; doi: https://doi.org/10.1101/805945

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