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An enhancer:involucrin regulatory module impacts human skin barrier adaptation out-of-Africa and modifies atopic dermatitis risk
Mary Elizabeth Mathyer, Erin A. Brettmann, Alina D. Schmidt, Zane A. Goodwin, Ashley M. Quiggle, Inez Y. Oh, Eric Tycksen, Lisa Zhou, Yeriel D. Estrada, X.F. Colin C. Wong, Simon L.I.J. Denil, Scot A. Matkovich, Avner Shemer, John E. A. Common, Emma Guttman-Yassky, View ORCID ProfileCristina de Guzman Strong
doi: https://doi.org/10.1101/816520
Mary Elizabeth Mathyer
1Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110 USA
Erin A. Brettmann
1Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110 USA
Alina D. Schmidt
1Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110 USA
Zane A. Goodwin
1Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110 USA
Ashley M. Quiggle
1Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110 USA
Inez Y. Oh
1Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110 USA
Eric Tycksen
4McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO 63110, USA
Lisa Zhou
5Department of Dermatology, Icahn School of Medicine at Mt. Sinai, New York, NY 10029 USA
Yeriel D. Estrada
5Department of Dermatology, Icahn School of Medicine at Mt. Sinai, New York, NY 10029 USA
X.F. Colin C. Wong
6Skin Research Institute of Singapore, A*STAR, Singapore 138648, Singapore
Simon L.I.J. Denil
6Skin Research Institute of Singapore, A*STAR, Singapore 138648, Singapore
Scot A. Matkovich
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
Avner Shemer
7Tel-Aviv University, Tel-Aviv, Israel
John E. A. Common
6Skin Research Institute of Singapore, A*STAR, Singapore 138648, Singapore
Emma Guttman-Yassky
5Department of Dermatology, Icahn School of Medicine at Mt. Sinai, New York, NY 10029 USA
Cristina de Guzman Strong
1Division of Dermatology, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
2Center for Pharmacogenomics, Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA
3Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110 USA
Article usage
Posted November 05, 2019.
An enhancer:involucrin regulatory module impacts human skin barrier adaptation out-of-Africa and modifies atopic dermatitis risk
Mary Elizabeth Mathyer, Erin A. Brettmann, Alina D. Schmidt, Zane A. Goodwin, Ashley M. Quiggle, Inez Y. Oh, Eric Tycksen, Lisa Zhou, Yeriel D. Estrada, X.F. Colin C. Wong, Simon L.I.J. Denil, Scot A. Matkovich, Avner Shemer, John E. A. Common, Emma Guttman-Yassky, Cristina de Guzman Strong
bioRxiv 816520; doi: https://doi.org/10.1101/816520
An enhancer:involucrin regulatory module impacts human skin barrier adaptation out-of-Africa and modifies atopic dermatitis risk
Mary Elizabeth Mathyer, Erin A. Brettmann, Alina D. Schmidt, Zane A. Goodwin, Ashley M. Quiggle, Inez Y. Oh, Eric Tycksen, Lisa Zhou, Yeriel D. Estrada, X.F. Colin C. Wong, Simon L.I.J. Denil, Scot A. Matkovich, Avner Shemer, John E. A. Common, Emma Guttman-Yassky, Cristina de Guzman Strong
bioRxiv 816520; doi: https://doi.org/10.1101/816520
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