New Results
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates
View ORCID ProfileM. Bourdenx, A. Nioche, View ORCID ProfileS. Dovero, View ORCID ProfileM.-L. Arotcarena, S. Camus, View ORCID ProfileG. Porras, View ORCID ProfileM.-L. Thiolat, View ORCID ProfileN. P. Rougier, View ORCID ProfileA. Prigent, View ORCID ProfileP. Aubert, View ORCID ProfileS. Bohic, View ORCID ProfileC. Sandt, View ORCID ProfileF. Laferrière, View ORCID ProfileE. Doudnikoff, View ORCID ProfileN. Kruse, View ORCID ProfileB. Mollenhauer, View ORCID ProfileS. Novello, View ORCID ProfileM. Morari, View ORCID ProfileT. Leste-Lasserre, View ORCID ProfileI. Trigo Damas, M. Goillandeau, View ORCID ProfileC. Perier, C. Estrada, View ORCID ProfileN. Garcia-Carrillo, View ORCID ProfileA. Recasens, View ORCID ProfileN. N. Vaikath, O. M. A. El-Agnaf, View ORCID ProfileM. Trinidad Herrero, View ORCID ProfileP. Derkinderen, View ORCID ProfileM. Vila, J. A. Obeso, View ORCID ProfileB. Dehay, View ORCID ProfileE. Bezard
doi: https://doi.org/10.1101/825216
M. Bourdenx
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
A. Nioche
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
3Institut Jean Nicod, Département d’études cognitives, ENS, EHESS, PSL Research University, 75005 Paris, France
4Institut Jean Nicod, Département d’études cognitives, CNRS, UMR 8129;
S. Dovero
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
M.-L. Arotcarena
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
S. Camus
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
G. Porras
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
M.-L. Thiolat
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
N. P. Rougier
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
5INRIA Bordeaux Sud-Ouest, 33405 Talence, France
A. Prigent
6Inserm, U913, Nantes F-44035, France; Nantes University, Nantes F-44035, France; CHU Nantes, Department of Neurology, Nantes F-44093, France
P. Aubert
6Inserm, U913, Nantes F-44035, France; Nantes University, Nantes F-44035, France; CHU Nantes, Department of Neurology, Nantes F-44093, France
S. Bohic
7EA-7442 Rayonnement Synchrotron et Recherche Medicale, RSRM, University of Grenoble Alpes, 38000 Grenoble, France
C. Sandt
8SMIS beamline, Synchrotron SOLEIL, l’orme des merisiers, 91192 Gif sur Yvette, France
F. Laferrière
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
E. Doudnikoff
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
N. Kruse
9Paracelsus-Elena-Klinik, Kassel, Germany; University Medical Center Goettingen, Institute of Neuropathology, Goettingen, Germany
B. Mollenhauer
9Paracelsus-Elena-Klinik, Kassel, Germany; University Medical Center Goettingen, Institute of Neuropathology, Goettingen, Germany
S. Novello
10Department of Medical Sciences, Section of Pharmacology, University of Ferrara, via Fossato di Mortara 17-19, 44121 Ferrara, Italy
11Neuroscience Center and National Institute of Neuroscience, University of Ferrara, via Fossato di Mortara 17-19, 44121 Ferrara, Italy
M. Morari
10Department of Medical Sciences, Section of Pharmacology, University of Ferrara, via Fossato di Mortara 17-19, 44121 Ferrara, Italy
11Neuroscience Center and National Institute of Neuroscience, University of Ferrara, via Fossato di Mortara 17-19, 44121 Ferrara, Italy
T. Leste-Lasserre
12INSERM, Neurocentre Magendie, U1215, Physiopathologie de la Plasticité Neuronale, F-33000 Bordeaux, France
I. Trigo Damas
13HM CINAC, HM Puerta del Sur and CEU-San Pablo University Madrid, E-28938 Mostoles, Spain
14Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Instituto Carlos III, Spain
M. Goillandeau
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
C. Perier
14Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Instituto Carlos III, Spain
15Neurodegenerative Diseases Research Group, Vall d’Hebron Research Institute (VHIR)-Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain
C. Estrada
16Clinical and Experimental Neuroscience Unit, School of Medicine, Biomedical Research Institute of Murcia (IMIB), University of Murcia, Campus Mare Nostrum, 30071 Murcia, Spain
17Institute of Research on Aging, School of Medicine, University of Murcia, 30071 Murcia, Spain
N. Garcia-Carrillo
18Centro Experimental en Investigaciones Biomédica (CEIB), Universidad de Murcia, Murcia, Spain
A. Recasens
14Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Instituto Carlos III, Spain
15Neurodegenerative Diseases Research Group, Vall d’Hebron Research Institute (VHIR)-Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain
N. N. Vaikath
19Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Education City, Qatar
O. M. A. El-Agnaf
19Neurological Disorders Research Center, Qatar Biomedical Research Institute (QBRI), Hamad Bin Khalifa University (HBKU), Education City, Qatar
M. Trinidad Herrero
16Clinical and Experimental Neuroscience Unit, School of Medicine, Biomedical Research Institute of Murcia (IMIB), University of Murcia, Campus Mare Nostrum, 30071 Murcia, Spain
17Institute of Research on Aging, School of Medicine, University of Murcia, 30071 Murcia, Spain
P. Derkinderen
6Inserm, U913, Nantes F-44035, France; Nantes University, Nantes F-44035, France; CHU Nantes, Department of Neurology, Nantes F-44093, France
M. Vila
14Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Instituto Carlos III, Spain
15Neurodegenerative Diseases Research Group, Vall d’Hebron Research Institute (VHIR)-Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Barcelona, Spain
20Department of Biochemistry and Molecular Biology, Autonomous University of Barcelona (UAB), Barcelona, Spain
21Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain
J. A. Obeso
13HM CINAC, HM Puerta del Sur and CEU-San Pablo University Madrid, E-28938 Mostoles, Spain
14Center for Networked Biomedical Research on Neurodegenerative Diseases (CIBERNED), Instituto Carlos III, Spain
B. Dehay
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
E. Bezard
1Univ. de Bordeaux, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
2CNRS, Institut des Maladies Neurodégénératives, UMR 5293, F-33000 Bordeaux, France
Article usage
Posted October 31, 2019.
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates
M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. Trinidad Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard
bioRxiv 825216; doi: https://doi.org/10.1101/825216
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in non-human primates
M. Bourdenx, A. Nioche, S. Dovero, M.-L. Arotcarena, S. Camus, G. Porras, M.-L. Thiolat, N. P. Rougier, A. Prigent, P. Aubert, S. Bohic, C. Sandt, F. Laferrière, E. Doudnikoff, N. Kruse, B. Mollenhauer, S. Novello, M. Morari, T. Leste-Lasserre, I. Trigo Damas, M. Goillandeau, C. Perier, C. Estrada, N. Garcia-Carrillo, A. Recasens, N. N. Vaikath, O. M. A. El-Agnaf, M. Trinidad Herrero, P. Derkinderen, M. Vila, J. A. Obeso, B. Dehay, E. Bezard
bioRxiv 825216; doi: https://doi.org/10.1101/825216
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