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MoBPS - Modular Breeding Program Simulator

View ORCID ProfileT. Pook, M. Schlather, H. Simianer
doi: https://doi.org/10.1101/829333
T. Pook
*Department of Animal Sciences, Animal Breeding and Genetics Group, University of Goettingen, 37075 Goettingen, Germany
†Center for Integrated Breeding Research, University of Goettingen, 37075 Goettingen, Germany
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  • For correspondence: torsten.pook@uni-goettingen.de
M. Schlather
†Center for Integrated Breeding Research, University of Goettingen, 37075 Goettingen, Germany
‡Stochastics and Its Applications Group, University of Mannheim, 68131 Mannheim, Germany
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H. Simianer
*Department of Animal Sciences, Animal Breeding and Genetics Group, University of Goettingen, 37075 Goettingen, Germany
†Center for Integrated Breeding Research, University of Goettingen, 37075 Goettingen, Germany
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ABSTRACT

The R-package MoBPS provides a computationally efficient and flexible framework to simulate complex breeding programs and compare their economic and genetic impact. Simulations are performed on the base of individuals and haplotypes are calculated on-the-fly by only saving founder haplotypes, points of recombination and mutations. MoBPS utilizes a highly efficient implementation with bit-wise storage of data and matrix multiplications from the associated R-package miraculix allowing to handle large scale populations. The modular structure of MoBPS allows to combine rather coarse simulations, as needed to generate founder populations, with a very detailed modeling of todays’ complex breeding programs, making use of all available biotechnologies. MoBPS provides pre-implemented functions for common breeding practices such as optimum genetic contributions and single-step GBLUP but also allows the user to replace certain steps with personalized and/or self-written solutions.

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  • https://github.com/tpook92/MoBPS

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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
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Posted November 06, 2019.
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MoBPS - Modular Breeding Program Simulator
T. Pook, M. Schlather, H. Simianer
bioRxiv 829333; doi: https://doi.org/10.1101/829333
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MoBPS - Modular Breeding Program Simulator
T. Pook, M. Schlather, H. Simianer
bioRxiv 829333; doi: https://doi.org/10.1101/829333

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