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HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite
View ORCID ProfileBartek Nogal, Laura E. McCoy, Marit J. van Gils, View ORCID ProfileChristopher A. Cottrell, James E. Voss, Raiees Andrabi, View ORCID ProfileMatthias Pauthner, Chi-Hui Liang, Terrence Messmer, Rebecca Nedellec, Mia Shin, View ORCID ProfileHannah L. Turner, View ORCID ProfileGabriel Ozorowski, Rogier W. Sanders, Dennis R. Burton, View ORCID ProfileAndrew B. Ward
doi: https://doi.org/10.1101/831008
Bartek Nogal
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Laura E. McCoy
2Division of Infection and Immunity, UCL, London, UK
Marit J. van Gils
3Department of Medical Microbiology, Amsterdam UMC, Location AMC, University of Amsterdam, 1105AZ, Amsterdam, The Netherlands.
Christopher A. Cottrell
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
James E. Voss
4Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Raiees Andrabi
4Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Matthias Pauthner
4Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Chi-Hui Liang
4Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Terrence Messmer
4Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Rebecca Nedellec
4Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Mia Shin
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Hannah L. Turner
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
Gabriel Ozorowski
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
Rogier W. Sanders
3Department of Medical Microbiology, Amsterdam UMC, Location AMC, University of Amsterdam, 1105AZ, Amsterdam, The Netherlands.
Dennis R. Burton
4Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
7Ragon Institute of MGH, MIT and Harvard, Cambridge, MA0239, USA
Andrew B. Ward
1Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, CA 92037, USA
5International AIDS Vaccine Initiative - Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA
6Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA
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Posted November 05, 2019.
HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite
Bartek Nogal, Laura E. McCoy, Marit J. van Gils, Christopher A. Cottrell, James E. Voss, Raiees Andrabi, Matthias Pauthner, Chi-Hui Liang, Terrence Messmer, Rebecca Nedellec, Mia Shin, Hannah L. Turner, Gabriel Ozorowski, Rogier W. Sanders, Dennis R. Burton, Andrew B. Ward
bioRxiv 831008; doi: https://doi.org/10.1101/831008
HIV Envelope Trimer-Elicited Autologous Neutralizing Antibodies Bind a Region Overlapping the N332 Glycan Supersite
Bartek Nogal, Laura E. McCoy, Marit J. van Gils, Christopher A. Cottrell, James E. Voss, Raiees Andrabi, Matthias Pauthner, Chi-Hui Liang, Terrence Messmer, Rebecca Nedellec, Mia Shin, Hannah L. Turner, Gabriel Ozorowski, Rogier W. Sanders, Dennis R. Burton, Andrew B. Ward
bioRxiv 831008; doi: https://doi.org/10.1101/831008
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