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Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits
Sebastian Akle, View ORCID ProfileSung Chun, Athanasios Teodosiadis, Brian E. Cade, Heming Wang, Tamar Sofer, Daniel S. Evans, Katie L. Stone, Sina A. Gharib, Sutapa Mukherjee, Lyle J. Palmer, David Hillman, Jerome I. Rotter, John A. Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R. Sunyaev
doi: https://doi.org/10.1101/832162
Sebastian Akle
1Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA, USA
2Division of Genetics, Brigham and Women’s Hospital, Boston, MA, USA
3Altius Institute for Biomedical Sciences, Seattle, WA, USA
Sung Chun
2Division of Genetics, Brigham and Women’s Hospital, Boston, MA, USA
3Altius Institute for Biomedical Sciences, Seattle, WA, USA
4Division of Pulmonary Medicine, Boston Children’s Hospital, Boston, MA, USA
Athanasios Teodosiadis
3Altius Institute for Biomedical Sciences, Seattle, WA, USA
Brian E. Cade
5Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA
6Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
7Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA
Heming Wang
5Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA
6Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
7Program in Medical and Population Genetics, Broad Institute, Cambridge, MA, USA
Tamar Sofer
5Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA
8Department of Medicine, Harvard Medical School, Boston, MA, USA
Daniel S. Evans
9California Pacific Medical Center Research Institute, San Francisco, CA, USA
Katie L. Stone
9California Pacific Medical Center Research Institute, San Francisco, CA, USA
Sina A. Gharib
10Division of Pulmonary, Critical Care, and Sleep Medicine, University of Washington, Seattle, WA, USA
11Computational Medicine Core at Center for Lung Biology, University of Washington, Seattle, WA, USA
Sutapa Mukherjee
12Respiratory and Sleep Services, Southern Adelaide Local Health Network, Adelaide, South Australia, Australia
13Adelaide Institute for Sleep Health, Flinders University, Adelaide, South Australia, Australia
Lyle J. Palmer
14School of Public Health, University of Adelaide, Adelaide, South Australia, Australia
David Hillman
15Centre for Sleep Science, University of Western Australia, Perth, Australia
16Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, Australia
Jerome I. Rotter
17Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center, Torrance, California 90501, USA
John A. Stamatoyannopoulos
3Altius Institute for Biomedical Sciences, Seattle, WA, USA
18Departments of Medicine and Genome Sciences, University of Washington, Seattle, Washington
Susan Redline
5Division of Sleep and Circadian Disorders, Brigham and Women’s Hospital, Boston, MA, USA
6Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA
19Division of Pulmonary, Critical Care, and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA
Chris Cotsapas
3Altius Institute for Biomedical Sciences, Seattle, WA, USA
20Broad Institute of Harvard and MIT, Cambridge, MA, USA
21Department of Neurology, Yale School of Medicine, New Haven, CT, USA
22Department of Genetics, Yale School of Medicine, New Haven, CT, USA
Shamil R. Sunyaev
2Division of Genetics, Brigham and Women’s Hospital, Boston, MA, USA
3Altius Institute for Biomedical Sciences, Seattle, WA, USA
23Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA
Posted November 07, 2019.
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits
Sebastian Akle, Sung Chun, Athanasios Teodosiadis, Brian E. Cade, Heming Wang, Tamar Sofer, Daniel S. Evans, Katie L. Stone, Sina A. Gharib, Sutapa Mukherjee, Lyle J. Palmer, David Hillman, Jerome I. Rotter, John A. Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R. Sunyaev
bioRxiv 832162; doi: https://doi.org/10.1101/832162
Leveraging pleiotropy to discover and interpret GWAS results for sleep-associated traits
Sebastian Akle, Sung Chun, Athanasios Teodosiadis, Brian E. Cade, Heming Wang, Tamar Sofer, Daniel S. Evans, Katie L. Stone, Sina A. Gharib, Sutapa Mukherjee, Lyle J. Palmer, David Hillman, Jerome I. Rotter, John A. Stamatoyannopoulos, Susan Redline, Chris Cotsapas, Shamil R. Sunyaev
bioRxiv 832162; doi: https://doi.org/10.1101/832162
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