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Synaptogenic activity of the axon guidance molecule Robo2 is critical for hippocampal circuit function

Heike Blockus, Sebastian V. Rolotti, Miklos Szoboszlay, Tiffany Ming, Anna Schroeder, Kristel M. Vennekens, Phinikoula Katsamba, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen, Barry Honig, Lawrence Shapiro, Joris de Wit, Attila Losonczy, View ORCID ProfileFranck Polleux
doi: https://doi.org/10.1101/840710
Heike Blockus
1Department of Neuroscience, Columbia University, New York, NY 10027, USA
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
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Sebastian V. Rolotti
1Department of Neuroscience, Columbia University, New York, NY 10027, USA
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
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Miklos Szoboszlay
1Department of Neuroscience, Columbia University, New York, NY 10027, USA
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
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Tiffany Ming
1Department of Neuroscience, Columbia University, New York, NY 10027, USA
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
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Anna Schroeder
4VIB Center for Brain and Disease Research, Herestraat 49, 3000 Leuven, Belgium
5Department of Neurosciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium
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Kristel M. Vennekens
4VIB Center for Brain and Disease Research, Herestraat 49, 3000 Leuven, Belgium
5Department of Neurosciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium
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Phinikoula Katsamba
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
6Department of Biochemistry and Biophysics, Columbia University, New York, NY 10027, USA
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Fabiana Bahna
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
6Department of Biochemistry and Biophysics, Columbia University, New York, NY 10027, USA
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Seetha Mannepalli
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
6Department of Biochemistry and Biophysics, Columbia University, New York, NY 10027, USA
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Goran Ahlsen
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
6Department of Biochemistry and Biophysics, Columbia University, New York, NY 10027, USA
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Barry Honig
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
6Department of Biochemistry and Biophysics, Columbia University, New York, NY 10027, USA
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Lawrence Shapiro
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
6Department of Biochemistry and Biophysics, Columbia University, New York, NY 10027, USA
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Joris de Wit
4VIB Center for Brain and Disease Research, Herestraat 49, 3000 Leuven, Belgium
5Department of Neurosciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium
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Attila Losonczy
1Department of Neuroscience, Columbia University, New York, NY 10027, USA
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
3Kavli Institute for Brain Science, Columbia University, New York, NY 10027, USA
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Franck Polleux
1Department of Neuroscience, Columbia University, New York, NY 10027, USA
2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
3Kavli Institute for Brain Science, Columbia University, New York, NY 10027, USA
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  • ORCID record for Franck Polleux
  • For correspondence: fp2304@columbia.edu
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Article Information

doi 
https://doi.org/10.1101/840710
History 
  • November 13, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Heike Blockus1,2,
  2. Sebastian V. Rolotti1,2,
  3. Miklos Szoboszlay1,2,
  4. Tiffany Ming1,2,
  5. Anna Schroeder4,5,
  6. Kristel M. Vennekens4,5,
  7. Phinikoula Katsamba2,6,
  8. Fabiana Bahna2,6,
  9. Seetha Mannepalli2,6,
  10. Goran Ahlsen2,6,
  11. Barry Honig2,6,
  12. Lawrence Shapiro2,6,
  13. Joris de Wit4,5,
  14. Attila Losonczy1,2,3 and
  15. Franck Polleux1,2,3,*
  1. 1Department of Neuroscience, Columbia University, New York, NY 10027, USA
  2. 2Zuckerman Mind Brain Behavior Institute, Columbia University, New York, NY 10027, USA
  3. 3Kavli Institute for Brain Science, Columbia University, New York, NY 10027, USA
  4. 4VIB Center for Brain and Disease Research, Herestraat 49, 3000 Leuven, Belgium
  5. 5Department of Neurosciences, KU Leuven, Herestraat 49, 3000 Leuven, Belgium
  6. 6Department of Biochemistry and Biophysics, Columbia University, New York, NY 10027, USA
  1. ↵*Address correspondence to: Franck Polleux, Ph.D., Columbia University, Department of Neuroscience, Mortimer B. Zuckerman Mind Brain Behavior Institute, Kavli Institute for Brain Science, Jerome L. Greene Science Center, 3227 Broadway, L-5-050, MC 9853, New York, NY 10027, fp2304{at}columbia.edu
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Posted November 13, 2019.
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Synaptogenic activity of the axon guidance molecule Robo2 is critical for hippocampal circuit function
Heike Blockus, Sebastian V. Rolotti, Miklos Szoboszlay, Tiffany Ming, Anna Schroeder, Kristel M. Vennekens, Phinikoula Katsamba, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen, Barry Honig, Lawrence Shapiro, Joris de Wit, Attila Losonczy, Franck Polleux
bioRxiv 840710; doi: https://doi.org/10.1101/840710
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Synaptogenic activity of the axon guidance molecule Robo2 is critical for hippocampal circuit function
Heike Blockus, Sebastian V. Rolotti, Miklos Szoboszlay, Tiffany Ming, Anna Schroeder, Kristel M. Vennekens, Phinikoula Katsamba, Fabiana Bahna, Seetha Mannepalli, Goran Ahlsen, Barry Honig, Lawrence Shapiro, Joris de Wit, Attila Losonczy, Franck Polleux
bioRxiv 840710; doi: https://doi.org/10.1101/840710

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