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Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor

Tiphaine Péresse, David Kovacs, Mélody Subra, Joëlle Bigay, Meng-Chen Tsai, Joël Polidori, Romain Gautier, Sandy Desrat, Lucile Fleuriot, Delphine Debayle, Marc Litaudon, Van-Cuong Pham, Jérôme Bignon, Bruno Antonny, Fanny Roussi, View ORCID ProfileBruno Mesmin
doi: https://doi.org/10.1101/844548
Tiphaine Péresse
1Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France
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David Kovacs
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Mélody Subra
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Joëlle Bigay
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Meng-Chen Tsai
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Joël Polidori
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Romain Gautier
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Sandy Desrat
1Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France
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Lucile Fleuriot
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Delphine Debayle
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Marc Litaudon
1Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France
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Van-Cuong Pham
3Advanced Center for Bioorganic Chemistry of the Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, 8404, Caugiay, Hanoi, Vietnam
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Jérôme Bignon
1Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France
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Bruno Antonny
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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Fanny Roussi
1Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France
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  • For correspondence: mesmin@ipmc.cnrs.fr fanny.roussi@cnrs.fr
Bruno Mesmin
2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
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  • ORCID record for Bruno Mesmin
  • For correspondence: mesmin@ipmc.cnrs.fr fanny.roussi@cnrs.fr
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Article Information

doi 
https://doi.org/10.1101/844548
History 
  • November 20, 2019.
Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.

Author Information

  1. Tiphaine Péresse1,#,
  2. David Kovacs2,
  3. Mélody Subra2,
  4. Joëlle Bigay2,
  5. Meng-Chen Tsai2,
  6. Joël Polidori2,
  7. Romain Gautier2,
  8. Sandy Desrat1,
  9. Lucile Fleuriot2,
  10. Delphine Debayle2,
  11. Marc Litaudon1,
  12. Van-Cuong Pham3,
  13. Jérôme Bignon1,
  14. Bruno Antonny2,
  15. Fanny Roussi1,* and
  16. Bruno Mesmin2,*
  1. 1Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France
  2. 2Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France
  3. 3Advanced Center for Bioorganic Chemistry of the Institute of Marine Biochemistry, Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, 8404, Caugiay, Hanoi, Vietnam
  1. ↵*To whom correspondence should be addressed: Bruno Mesmin: Université Côte d’Azur, Inserm, CNRS, Institut de Pharmacologie Moléculaire et Cellulaire, Valbonne, France; mesmin{at}ipmc.cnrs.fr; Tel. (33) 493957767; Fax. (33) 493957708. Fanny Roussi: Institut de Chimie des Substances Naturelles, CNRS, Université Paris-Saclay, Gif-sur-Yvette, France; fanny.roussi{at}cnrs.fr; Tel. (33) 169823121
  • ↵# Département de Chimie, Ecole Normale Supérieure, Université PSL, Sorbonne Université, CNRS, Paris, France

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Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor
Tiphaine Péresse, David Kovacs, Mélody Subra, Joëlle Bigay, Meng-Chen Tsai, Joël Polidori, Romain Gautier, Sandy Desrat, Lucile Fleuriot, Delphine Debayle, Marc Litaudon, Van-Cuong Pham, Jérôme Bignon, Bruno Antonny, Fanny Roussi, Bruno Mesmin
bioRxiv 844548; doi: https://doi.org/10.1101/844548
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Molecular and cellular dissection of the OSBP cycle through a fluorescent inhibitor
Tiphaine Péresse, David Kovacs, Mélody Subra, Joëlle Bigay, Meng-Chen Tsai, Joël Polidori, Romain Gautier, Sandy Desrat, Lucile Fleuriot, Delphine Debayle, Marc Litaudon, Van-Cuong Pham, Jérôme Bignon, Bruno Antonny, Fanny Roussi, Bruno Mesmin
bioRxiv 844548; doi: https://doi.org/10.1101/844548

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