Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Genetic Association Study of Childhood Aggression across raters, instruments and age

View ORCID ProfileHill F. Ip, Camiel M. van der Laan, Eva M. L. Krapohl, Isabell Brikell, Sánchez-Mora Cristina, Ilja M. Nolte, Beate St Pourcain, Koen Bolhuis, Teemu Palviainen, Hadi Zafarmand, Lucía Colodro-Conde, Scott Gordon, Tetyana Zayats, Fazil Aliev, Chang Jiang, Carol A. Wang, Gretchen Saunders, Ville Karhunen, Anke R. Hammerschlag, Daniel E. Adkins, View ORCID ProfileRichard Border, Roseann E. Peterson, Joseph A. Prinz, Elisabeth Thiering, Ilkka Seppälä, Vilor-Tejedor Natàlia, Tarunveer S. Ahluwalia, Felix R. Day, Jouke-Jan Hottenga, Andrea G. Allegrini, View ORCID ProfileKaili Rimfeld, Qi Chen, Yi Lu, Joanna Martin, María Soler Artigas, Paula Rovira, Rosa Bosch, Gemma Español, Josep Antoni Ramos Quiroga, Alexander Neumann, Judith Ensink, Katrina Grasby, José J. Morosoli, Xiaoran Tong, Shelby Marrington, Christel Middeldorp, James G. Scott, Anna Vinkhuyzen, Andrey A. Shabalin, Robin Corley, View ORCID ProfileLuke M. Evans, Karen Sugden, Silvia Alemany, Lærke Sass, Rebecca Vinding, View ORCID ProfileKate Ruth, Jess Tyrrell, Gareth E. Davies, Erik A. Ehli, Fiona A. Hagenbeek, Eveline De Zeeuw, Toos C.E.M. Van Beijsterveldt, Henrik Larsson, Harold Snieder, Frank C. Verhulst, Najaf Amin, Alyce M. Whipp, Tellervo Korhonen, View ORCID ProfileEero Vuoksimaa, Richard J. Rose, André G. Uitterlinden, Andrew C. Heath, Pamela Madden, Jan Haavik, Jennifer R. Harris, Øyvind Helgeland, Stefan Johansson, Gun Peggy S. Knudsen, Pal Rasmus Njolstad, Qing Lu, Alina Rodriguez, Anjali K. Henders, Abdullah Mamun, Jackob M. Najman, Sandy Brown, Christian Hopfer, Kenneth Krauter, Chandra Reynolds, Andrew Smolen, Michael Stallings, Sally Wadsworth, Tamara L. Wall, Judy L. Silberg, Allison Miller, Liisa Keltikangas-Järvinen, View ORCID ProfileChristian Hakulinen, Laura Pulkki-Råback, Alexandra Havdahl, Per Magnus, Olli T. Raitakari, John R.B. Perry, Sabrina Llop, Maria-Jose Lopez-Espinosa, Klaus Bønnelykke, View ORCID ProfileHans Bisgaard, Jordi Sunyer, Terho Lehtimäki, Louise Arseneault, Marie Standl, Joachim Heinrich, View ORCID ProfileJoseph Boden, John Pearson, L John Horwood, View ORCID ProfileMartin Kennedy, Richie Poulton, Lindon J. Eaves, Hermine H. Maes, John Hewitt, View ORCID ProfileWilliam E. Copeland, Elizabeth J. Costello, Gail M. Williams, View ORCID ProfileNaomi Wray, Marjo-Riitta Järvelin, Matt McGue, William Iacono, Avshalom Caspi, Terrie E. Moffitt, Andrew Whitehouse, Craig E. Pennell, Kelly L. Klump, S. Alexandra Burt, Danielle M. Dick, Ted Reichborn-Kjennerud, Nicholas G. Martin, Sarah E. Medland, Tanja Vrijkotte, View ORCID ProfileJaakko Kaprio, Henning Tiemeier, George Davey Smith, Catharina A. Hartman, Albertine J. Oldehinkel, Miquel Casas, Marta Ribasés, Paul Lichtenstein, Sebastian Lundström, Robert Plomin, Meike Bartels, Michel G. Nivard, View ORCID ProfileDorret I. Boomsma
doi: https://doi.org/10.1101/854927
Hill F. Ip
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Hill F. Ip
Camiel M. van der Laan
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
2Netherlands Institute for the Study of Crime and Law Enforcement
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eva M. L. Krapohl
3Institute of Psychiatry, Psychology and Neuroscience, King’s College London, United Kingdom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Isabell Brikell
4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sánchez-Mora Cristina
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
6Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain
7Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ilja M. Nolte
8Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Beate St Pourcain
9MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK
10Max Planck Institute for Psycholinguistics, The Netherlands
11Donders Institute for Brain, Cognition and Behaviour, Radboud University, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Koen Bolhuis
12Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Teemu Palviainen
13Institute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hadi Zafarmand
14Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
15Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lucía Colodro-Conde
16QIMR Berghofer Medical Research Institute, Brisbane, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Scott Gordon
16QIMR Berghofer Medical Research Institute, Brisbane, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tetyana Zayats
17Department of Biomedicine, University of Bergen, Norway
18Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA
19Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fazil Aliev
20Department of Psychology, Virginia Commonwealth University, USA
21Faculty of Business, Karabuk University, Turkey
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chang Jiang
22Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, USA
23Department of Biostatistics, University of Florida, Gainesville, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Carol A. Wang
24School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gretchen Saunders
25Department of Psychology, University of Minnesota, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ville Karhunen
26Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, W2 1PG, United Kingdom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anke R. Hammerschlag
27Child Health Research Centre, the University of Queensland, Brisbane, QLD, Australia
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
28Amsterdam Public Health Research Institute, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Daniel E. Adkins
29Department of Sociology, College of Social and Behavioral Science, University of Utah
30Department of Psychiatry, School of Medicine, University of Utah
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Richard Border
31Institute for Behavioral Genetics, University of Colorado Boulder, Colorado, USA
32Department of Psychology and Neuroscience, University of Colorado Boulder, Colorado, USA
33Department of Applied Mathematics, University of Colorado Boulder, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Richard Border
Roseann E. Peterson
34Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joseph A. Prinz
35Center for Genomic and Computational Biology, Duke University, Durham, NC, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Elisabeth Thiering
36Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany
37Ludwig-Maximilians-University of Munich, Dr. von Hauner Children’s Hospital, Division of Metabolic Diseases and Nutritional Medicine, Munich, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ilkka Seppälä
38Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Vilor-Tejedor Natàlia
39ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain
40Universitat Pompeu Fabra (UPF), Barcelona, Spain
41CIBER Epidemiología y Salud Pública (CIBERESP), Spain
42Centre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain
43Barcelona Beta Brain Research Center, Pasqual Maragall Foundation (FPM), Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tarunveer S. Ahluwalia
44COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
45Steno Diabetes Center Copenhagen, Gentofte, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Felix R. Day
46MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jouke-Jan Hottenga
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrea G. Allegrini
3Institute of Psychiatry, Psychology and Neuroscience, King’s College London, United Kingdom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kaili Rimfeld
3Institute of Psychiatry, Psychology and Neuroscience, King’s College London, United Kingdom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Kaili Rimfeld
Qi Chen
4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yi Lu
4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joanna Martin
4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
47MRC Centre for Neuropsychiatric Genetics and Genomics, Division of Psychological Medicine and Clinical Neurosciences, Cardiff University, Cardiff, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
María Soler Artigas
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
6Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain
7Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paula Rovira
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
6Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain
7Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rosa Bosch
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
6Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain
48Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gemma Español
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Josep Antoni Ramos Quiroga
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
6Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain
7Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
48Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alexander Neumann
12Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, Netherlands
49Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Qc, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Judith Ensink
50Department of Child and Adolescent Psychiatry, Academic Medical Center, Amsterdam, The Netherlands
51De Bascule, Academic centre for Child and Adolescent Psychiatry, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Katrina Grasby
16QIMR Berghofer Medical Research Institute, Brisbane, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
José J. Morosoli
16QIMR Berghofer Medical Research Institute, Brisbane, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Xiaoran Tong
22Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, USA
23Department of Biostatistics, University of Florida, Gainesville, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shelby Marrington
52School of Public Health, Faculty of Medicine, The University of Queensland, Herston 4006, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christel Middeldorp
27Child Health Research Centre, the University of Queensland, Brisbane, QLD, Australia
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
53Children’s Health Queensland Hospital and Health Service, Child and Youth Mental Health Service, Brisbane, QLD, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
James G. Scott
52School of Public Health, Faculty of Medicine, The University of Queensland, Herston 4006, Australia
54Metro North Mental Health, University of Queensland, QLD, Australia
55Queensland Centre for Mental Health Research, QLD, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anna Vinkhuyzen
56Institute for Molecular Bioscience, University of Queensland, QLD, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrey A. Shabalin
30Department of Psychiatry, School of Medicine, University of Utah
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robin Corley
31Institute for Behavioral Genetics, University of Colorado Boulder, Colorado, USA
57Department of Ecology and Evolutionary Biology, University of Colorado Boulder, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Luke M. Evans
31Institute for Behavioral Genetics, University of Colorado Boulder, Colorado, USA
57Department of Ecology and Evolutionary Biology, University of Colorado Boulder, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Luke M. Evans
Karen Sugden
58Department of Psychology and Neuroscience and Center for Genomic and Computational Biology, Duke University, Durham, NC, USA
35Center for Genomic and Computational Biology, Duke University, Durham, NC, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Silvia Alemany
39ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain
40Universitat Pompeu Fabra (UPF), Barcelona, Spain
41CIBER Epidemiología y Salud Pública (CIBERESP), Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lærke Sass
44COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Rebecca Vinding
44COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kate Ruth
59Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Kate Ruth
Jess Tyrrell
59Genetics of Complex Traits, University of Exeter Medical School, Royal Devon & Exeter Hospital, Exeter, EX2 5DW, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gareth E. Davies
60Avera Institute for Human Genetics, Sioux Falls, South Dakota, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Erik A. Ehli
60Avera Institute for Human Genetics, Sioux Falls, South Dakota, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Fiona A. Hagenbeek
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eveline De Zeeuw
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Toos C.E.M. Van Beijsterveldt
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Henrik Larsson
4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
61School of Medical Sciences, Orebro University, Orebro, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Harold Snieder
8Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Frank C. Verhulst
12Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, Netherlands
62Child and Adolescent Mental Health Centre, Mental Health Services Capital Region, Research Unit, Copenhagen University Hospital, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Najaf Amin
63Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alyce M. Whipp
13Institute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tellervo Korhonen
13Institute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eero Vuoksimaa
13Institute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Eero Vuoksimaa
Richard J. Rose
64Department of Psychological and Brain Sciences, Indiana University, Bloomington, IN, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
André G. Uitterlinden
63Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands
65Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands
66Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Leiden, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrew C. Heath
67Washington University, St Louis MO, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pamela Madden
67Washington University, St Louis MO, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jan Haavik
17Department of Biomedicine, University of Bergen, Norway
68Division of Psychiatry, Haukeland University Hospital, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jennifer R. Harris
69Division of Health Data and Digitalisation, The Norwegian Institute of Public Health, Oslo, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Øyvind Helgeland
70Department of Genetics and Bioinformatics, Division of Health Data and Digitalization, The Norwegian Institute of Public Health
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stefan Johansson
17Department of Biomedicine, University of Bergen, Norway
71K.G. Jebsen Centre for Neuropsychiatric Disorders, Department of Clinical Science, University of Bergen, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gun Peggy S. Knudsen
69Division of Health Data and Digitalisation, The Norwegian Institute of Public Health, Oslo, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pal Rasmus Njolstad
72Department of Clinical Science, University of Bergen, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Qing Lu
22Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, USA
23Department of Biostatistics, University of Florida, Gainesville, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alina Rodriguez
26Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, W2 1PG, United Kingdom
73School of Psychology, University of Lincoln, Lincolnshire, LN5 7AY, United Kingdom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anjali K. Henders
56Institute for Molecular Bioscience, University of Queensland, QLD, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Abdullah Mamun
74Institute for Social Science Research, University of Queensland, Long Pocket 4068, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jackob M. Najman
52School of Public Health, Faculty of Medicine, The University of Queensland, Herston 4006, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sandy Brown
75Department of Psychiatry, University of California, San Diego
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christian Hopfer
76University of Colorado School of Medicine, Aurora, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kenneth Krauter
77Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Chandra Reynolds
78Department of Psychology, University of California Riverside, Riverside, CA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrew Smolen
31Institute for Behavioral Genetics, University of Colorado Boulder, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Stallings
31Institute for Behavioral Genetics, University of Colorado Boulder, Colorado, USA
32Department of Psychology and Neuroscience, University of Colorado Boulder, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sally Wadsworth
31Institute for Behavioral Genetics, University of Colorado Boulder, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tamara L. Wall
75Department of Psychiatry, University of California, San Diego
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Judy L. Silberg
79Department of Human & Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
34Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Allison Miller
80Department of Pathology and Biomedical Science, and Carney Centre for Pharmacogenomics, University of Otago Christchurch, New Zealand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Liisa Keltikangas-Järvinen
81Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christian Hakulinen
81Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Christian Hakulinen
Laura Pulkki-Råback
81Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Alexandra Havdahl
82Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway
83Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Per Magnus
84Centre for Fertility and Health, Norwegian Institute of Public Health, Oslo, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Olli T. Raitakari
85Centre for Population Health Research, University of Turku and Turku University Hospital
86Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku
87Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
John R.B. Perry
46MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge Biomedical Campus, Cambridge, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sabrina Llop
88Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, Valencia, Spain
89Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maria-Jose Lopez-Espinosa
88Epidemiology and Environmental Health Joint Research Unit, FISABIO-Universitat Jaume I-Universitat de València, Valencia, Spain
89Spanish Consortium for Research on Epidemiology and Public Health (CIBERESP), Madrid, Spain
90Faculty of Nursing and Chiropody, Universitat de València, Valencia, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Klaus Bønnelykke
44COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hans Bisgaard
44COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Hans Bisgaard
Jordi Sunyer
39ISGlobal, Barcelona Institute for Global Health, Barcelona, Spain
40Universitat Pompeu Fabra (UPF), Barcelona, Spain
41CIBER Epidemiología y Salud Pública (CIBERESP), Spain
91IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Terho Lehtimäki
38Department of Clinical Chemistry, Fimlab Laboratories, and Finnish Cardiovascular Research Center - Tampere, Faculty of Medicine and Health Technology, Tampere University, Tampere 33520, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Louise Arseneault
92Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marie Standl
36Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joachim Heinrich
36Institute of Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany
93Institute and Outpatient Clinic for Occupational, Social and Environmental Medicine, University of Munich Medical Center, Ludwig-Maximilians-Universität München, Munich, Germany
94Allergy and Lung Health Unit, Melbourne School of Population and Global Health, University of Melbourne, Melbourne, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joseph Boden
95Christchurch Health and Development Study, Department of Psychological Medicine, University of Otago Christchurch, New Zealand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Joseph Boden
John Pearson
96Biostatistics and Computational Biology Unit, Department of Pathology and Biomedical Science, University of Otago Christchurch, New Zealand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L John Horwood
95Christchurch Health and Development Study, Department of Psychological Medicine, University of Otago Christchurch, New Zealand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Martin Kennedy
97Department of Pathology and Biomedical Science, and Carney Centre for Pharmacogenomics, University of Otago Christchurch, New Zealand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Martin Kennedy
Richie Poulton
98Dunedin Multidisciplinary Health and Development Research Unit, University of Otago, Dunedin, New Zealand
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lindon J. Eaves
79Department of Human & Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
34Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hermine H. Maes
79Department of Human & Molecular Genetics, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
34Department of Psychiatry, Virginia Institute for Psychiatric and Behavioral Genetics, Virginia Commonwealth University
99Massey Cancer Center, Virginia Commonwealth University
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
John Hewitt
31Institute for Behavioral Genetics, University of Colorado Boulder, Colorado, USA
32Department of Psychology and Neuroscience, University of Colorado Boulder, Colorado, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
William E. Copeland
100Department of Psychiatry, College of Medicine, University of Vermont
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for William E. Copeland
Elizabeth J. Costello
101Department of Psychiatry, School of Medicine, Duke University
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gail M. Williams
52School of Public Health, Faculty of Medicine, The University of Queensland, Herston 4006, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Naomi Wray
56Institute for Molecular Bioscience, University of Queensland, QLD, Australia
102Queensland Brain Institute, Institute for Molecular Bioscience, University of Queensland, St Lucia 4072, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Naomi Wray
Marjo-Riitta Järvelin
26Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, W2 1PG, United Kingdom
103Center for Life Course Health Research, Faculty of Medicine, University of Oulu, PO Box 8000, FI-90014 Oulun yliopisto, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Matt McGue
25Department of Psychology, University of Minnesota, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
William Iacono
25Department of Psychology, University of Minnesota, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Avshalom Caspi
58Department of Psychology and Neuroscience and Center for Genomic and Computational Biology, Duke University, Durham, NC, USA
92Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA
104Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, UK
35Center for Genomic and Computational Biology, Duke University, Durham, NC, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Terrie E. Moffitt
58Department of Psychology and Neuroscience and Center for Genomic and Computational Biology, Duke University, Durham, NC, USA
92Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA
104Social, Genetic, and Developmental Psychiatry Research Centre, Institute of Psychiatry, Psychology, and Neuroscience, King’s College London, UK
35Center for Genomic and Computational Biology, Duke University, Durham, NC, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Andrew Whitehouse
105Telethon Kids Institute, The University of Western Australia, Perth, Western Australia, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Craig E. Pennell
24School of Medicine and Public Health, Faculty of Medicine and Health, The University of Newcastle
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kelly L. Klump
106Department of Psychology, Michigan State University, East Lansing, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
S. Alexandra Burt
106Department of Psychology, Michigan State University, East Lansing, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Danielle M. Dick
20Department of Psychology, Virginia Commonwealth University, USA
107Department of Human and Molecular Genetics, Virginia Commonwealth University, Richmond, VA, USA
108College Behavioral and Emotional Health Institute, Virginia Commonwealth University, Richmond, VA, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ted Reichborn-Kjennerud
83Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway
109Institute of Clinical Medicine, University of Oslo, Oslo, Norway
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Nicholas G. Martin
16QIMR Berghofer Medical Research Institute, Brisbane, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sarah E. Medland
16QIMR Berghofer Medical Research Institute, Brisbane, Australia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tanja Vrijkotte
14Department of Public Health, Amsterdam Public Health Research Institute, Amsterdam UMC, location Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jaakko Kaprio
110Department of Public Health, Medical Faculty, University of Helsinki, Helsinki, Finland
13Institute for Molecular Medicine FIMM, HiLife, University of Helsinki, Helsinki, Finland
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Jaakko Kaprio
Henning Tiemeier
12Department of Child and Adolescent Psychiatry/Psychology, Erasmus University Medical Center, Rotterdam, Netherlands
111Department of Social and Behavioral Science, Harvard TH Chand School of Public Health, Boston, USA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
George Davey Smith
9MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK
112Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Catharina A. Hartman
113Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Albertine J. Oldehinkel
113Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Miquel Casas
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
6Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain
7Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
48Department of Psychiatry and Legal Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Marta Ribasés
5Department of Psychiatry, Hospital Universitari Vall d’Hebron, Barcelona, Spain
6Biomedical Network Research Centre on Mental Health (CIBERSAM), Instituto de Salud Carlos III, Barcelona, Spain
7Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d’Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Paul Lichtenstein
4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Sebastian Lundström
114Gillberg Neuropsychiatry Centre, University of Gothenburg, Gothenburg, Sweden
115Sweden Centre for Ethics, Law and Mental Health, University of Gothenburg, Gothenburg, Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Robert Plomin
3Institute of Psychiatry, Psychology and Neuroscience, King’s College London, United Kingdom
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Meike Bartels
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
28Amsterdam Public Health Research Institute, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: m.bartels@vu.nl m.g.nivard@vu.nl di.boomsma@vu.nl
Michel G. Nivard
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: m.bartels@vu.nl m.g.nivard@vu.nl di.boomsma@vu.nl
Dorret I. Boomsma
1Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
28Amsterdam Public Health Research Institute, Amsterdam, The Netherlands
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Dorret I. Boomsma
  • For correspondence: m.bartels@vu.nl m.g.nivard@vu.nl di.boomsma@vu.nl
  • Abstract
  • Full Text
  • Info/History
  • Metrics
  • Supplementary material
  • Preview PDF
Loading

Abstract

Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. We analyzed phenotype assessments for a total of 328 935 observations from 87 485 children aged between 1.5 and 18 years, while accounting for sample overlap. We also meta-analyzed within subsets of the data – i.e. within rater, instrument and age. SNP-heritability for the overall meta-analysis (AGGoverall) was 3.31% (SE=0.0038). We found no genome-wide significant SNPs for AGGoverall. The gene-based analysis returned three significant genes: ST3GAL3 (P=1.6E-06), PCDH7 (P=2.0E-06) and IPO13 (P=2.5E-06). All three genes have previously been associated with educational traits. Polygenic scores based on our GWAMA significantly predicted aggression in a holdout sample of children (variance explained = 0.44%) and in retrospectively assessed childhood aggression (variance explained = 0.20%). Genetic correlations (rg) among rater-specific assessment of AGG ranged from rg =0.46 between self- and teacher-assessment to rg =0.81 between mother- and teacher-assessment. We obtained moderate to strong rg’s with selected phenotypes from multiple domains, but hardly with any of the classical biomarkers thought to be associated with AGG. Significant genetic correlations were observed with most psychiatric and psychological traits (range |rg| : 0.19 – 1.00), except for obsessive-compulsive disorder. Aggression had a negative genetic correlation (rg =~ −0.5) with cognitive traits and age at first birth. Aggression was strongly genetically correlated with smoking phenotypes (range |rg| : 0.46 – 0.60). The genetic correlations between aggression and psychiatric disorders were weaker for teacher-reported AGG than for mother- and self-reported AGG. The current GWAMA of childhood aggression provides a powerful tool to interrogate the rater-specific genetic etiology of AGG.

Competing Interest Statement

Miquel Casas has received travel grants and research support from Eli Lilly and Co., Janssen-Cilag, Shire and Lundbeck and served as consultant for Eli Lilly and Co., Janssen-Cilag, Shire and Lundbeck. Josep Antoni Ramos Quiroga was on the speakers' bureau and/or acted as consultant Eli-Lilly, Janssen-Cilag, Novartis, Shire, Lundbeck, Almirall, Braingaze, Sincrolab, Medicine, Exeltis and Rubio in the last 5 years. He also received travel awards (air tickets + hotel) for taking part in psychiatric meetings from Janssen-Cilag, Rubio, Shire, Medice and Eli-Lilly. The Department of Psychiatry chaired by him received unrestricted educational and research support from the following companies in the last 5 years: Eli-Lilly, Lundbeck, Janssen-Cilag, Actelion, Shire, Ferrer, Oryzon, Roche, Psious, and Rubio.

Footnotes

  • ↵* These authors jointly supervised this work

  • Updated manuscript

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Back to top
PreviousNext
Posted February 20, 2021.
Download PDF

Supplementary Material

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Genetic Association Study of Childhood Aggression across raters, instruments and age
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Share
Genetic Association Study of Childhood Aggression across raters, instruments and age
Hill F. Ip, Camiel M. van der Laan, Eva M. L. Krapohl, Isabell Brikell, Sánchez-Mora Cristina, Ilja M. Nolte, Beate St Pourcain, Koen Bolhuis, Teemu Palviainen, Hadi Zafarmand, Lucía Colodro-Conde, Scott Gordon, Tetyana Zayats, Fazil Aliev, Chang Jiang, Carol A. Wang, Gretchen Saunders, Ville Karhunen, Anke R. Hammerschlag, Daniel E. Adkins, Richard Border, Roseann E. Peterson, Joseph A. Prinz, Elisabeth Thiering, Ilkka Seppälä, Vilor-Tejedor Natàlia, Tarunveer S. Ahluwalia, Felix R. Day, Jouke-Jan Hottenga, Andrea G. Allegrini, Kaili Rimfeld, Qi Chen, Yi Lu, Joanna Martin, María Soler Artigas, Paula Rovira, Rosa Bosch, Gemma Español, Josep Antoni Ramos Quiroga, Alexander Neumann, Judith Ensink, Katrina Grasby, José J. Morosoli, Xiaoran Tong, Shelby Marrington, Christel Middeldorp, James G. Scott, Anna Vinkhuyzen, Andrey A. Shabalin, Robin Corley, Luke M. Evans, Karen Sugden, Silvia Alemany, Lærke Sass, Rebecca Vinding, Kate Ruth, Jess Tyrrell, Gareth E. Davies, Erik A. Ehli, Fiona A. Hagenbeek, Eveline De Zeeuw, Toos C.E.M. Van Beijsterveldt, Henrik Larsson, Harold Snieder, Frank C. Verhulst, Najaf Amin, Alyce M. Whipp, Tellervo Korhonen, Eero Vuoksimaa, Richard J. Rose, André G. Uitterlinden, Andrew C. Heath, Pamela Madden, Jan Haavik, Jennifer R. Harris, Øyvind Helgeland, Stefan Johansson, Gun Peggy S. Knudsen, Pal Rasmus Njolstad, Qing Lu, Alina Rodriguez, Anjali K. Henders, Abdullah Mamun, Jackob M. Najman, Sandy Brown, Christian Hopfer, Kenneth Krauter, Chandra Reynolds, Andrew Smolen, Michael Stallings, Sally Wadsworth, Tamara L. Wall, Judy L. Silberg, Allison Miller, Liisa Keltikangas-Järvinen, Christian Hakulinen, Laura Pulkki-Råback, Alexandra Havdahl, Per Magnus, Olli T. Raitakari, John R.B. Perry, Sabrina Llop, Maria-Jose Lopez-Espinosa, Klaus Bønnelykke, Hans Bisgaard, Jordi Sunyer, Terho Lehtimäki, Louise Arseneault, Marie Standl, Joachim Heinrich, Joseph Boden, John Pearson, L John Horwood, Martin Kennedy, Richie Poulton, Lindon J. Eaves, Hermine H. Maes, John Hewitt, William E. Copeland, Elizabeth J. Costello, Gail M. Williams, Naomi Wray, Marjo-Riitta Järvelin, Matt McGue, William Iacono, Avshalom Caspi, Terrie E. Moffitt, Andrew Whitehouse, Craig E. Pennell, Kelly L. Klump, S. Alexandra Burt, Danielle M. Dick, Ted Reichborn-Kjennerud, Nicholas G. Martin, Sarah E. Medland, Tanja Vrijkotte, Jaakko Kaprio, Henning Tiemeier, George Davey Smith, Catharina A. Hartman, Albertine J. Oldehinkel, Miquel Casas, Marta Ribasés, Paul Lichtenstein, Sebastian Lundström, Robert Plomin, Meike Bartels, Michel G. Nivard, Dorret I. Boomsma
bioRxiv 854927; doi: https://doi.org/10.1101/854927
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Genetic Association Study of Childhood Aggression across raters, instruments and age
Hill F. Ip, Camiel M. van der Laan, Eva M. L. Krapohl, Isabell Brikell, Sánchez-Mora Cristina, Ilja M. Nolte, Beate St Pourcain, Koen Bolhuis, Teemu Palviainen, Hadi Zafarmand, Lucía Colodro-Conde, Scott Gordon, Tetyana Zayats, Fazil Aliev, Chang Jiang, Carol A. Wang, Gretchen Saunders, Ville Karhunen, Anke R. Hammerschlag, Daniel E. Adkins, Richard Border, Roseann E. Peterson, Joseph A. Prinz, Elisabeth Thiering, Ilkka Seppälä, Vilor-Tejedor Natàlia, Tarunveer S. Ahluwalia, Felix R. Day, Jouke-Jan Hottenga, Andrea G. Allegrini, Kaili Rimfeld, Qi Chen, Yi Lu, Joanna Martin, María Soler Artigas, Paula Rovira, Rosa Bosch, Gemma Español, Josep Antoni Ramos Quiroga, Alexander Neumann, Judith Ensink, Katrina Grasby, José J. Morosoli, Xiaoran Tong, Shelby Marrington, Christel Middeldorp, James G. Scott, Anna Vinkhuyzen, Andrey A. Shabalin, Robin Corley, Luke M. Evans, Karen Sugden, Silvia Alemany, Lærke Sass, Rebecca Vinding, Kate Ruth, Jess Tyrrell, Gareth E. Davies, Erik A. Ehli, Fiona A. Hagenbeek, Eveline De Zeeuw, Toos C.E.M. Van Beijsterveldt, Henrik Larsson, Harold Snieder, Frank C. Verhulst, Najaf Amin, Alyce M. Whipp, Tellervo Korhonen, Eero Vuoksimaa, Richard J. Rose, André G. Uitterlinden, Andrew C. Heath, Pamela Madden, Jan Haavik, Jennifer R. Harris, Øyvind Helgeland, Stefan Johansson, Gun Peggy S. Knudsen, Pal Rasmus Njolstad, Qing Lu, Alina Rodriguez, Anjali K. Henders, Abdullah Mamun, Jackob M. Najman, Sandy Brown, Christian Hopfer, Kenneth Krauter, Chandra Reynolds, Andrew Smolen, Michael Stallings, Sally Wadsworth, Tamara L. Wall, Judy L. Silberg, Allison Miller, Liisa Keltikangas-Järvinen, Christian Hakulinen, Laura Pulkki-Råback, Alexandra Havdahl, Per Magnus, Olli T. Raitakari, John R.B. Perry, Sabrina Llop, Maria-Jose Lopez-Espinosa, Klaus Bønnelykke, Hans Bisgaard, Jordi Sunyer, Terho Lehtimäki, Louise Arseneault, Marie Standl, Joachim Heinrich, Joseph Boden, John Pearson, L John Horwood, Martin Kennedy, Richie Poulton, Lindon J. Eaves, Hermine H. Maes, John Hewitt, William E. Copeland, Elizabeth J. Costello, Gail M. Williams, Naomi Wray, Marjo-Riitta Järvelin, Matt McGue, William Iacono, Avshalom Caspi, Terrie E. Moffitt, Andrew Whitehouse, Craig E. Pennell, Kelly L. Klump, S. Alexandra Burt, Danielle M. Dick, Ted Reichborn-Kjennerud, Nicholas G. Martin, Sarah E. Medland, Tanja Vrijkotte, Jaakko Kaprio, Henning Tiemeier, George Davey Smith, Catharina A. Hartman, Albertine J. Oldehinkel, Miquel Casas, Marta Ribasés, Paul Lichtenstein, Sebastian Lundström, Robert Plomin, Meike Bartels, Michel G. Nivard, Dorret I. Boomsma
bioRxiv 854927; doi: https://doi.org/10.1101/854927

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Genomics
Subject Areas
All Articles
  • Animal Behavior and Cognition (2513)
  • Biochemistry (4957)
  • Bioengineering (3456)
  • Bioinformatics (15148)
  • Biophysics (6868)
  • Cancer Biology (5365)
  • Cell Biology (7692)
  • Clinical Trials (138)
  • Developmental Biology (4509)
  • Ecology (7117)
  • Epidemiology (2059)
  • Evolutionary Biology (10193)
  • Genetics (7494)
  • Genomics (9758)
  • Immunology (4808)
  • Microbiology (13153)
  • Molecular Biology (5114)
  • Neuroscience (29321)
  • Paleontology (203)
  • Pathology (833)
  • Pharmacology and Toxicology (1458)
  • Physiology (2123)
  • Plant Biology (4723)
  • Scientific Communication and Education (1004)
  • Synthetic Biology (1336)
  • Systems Biology (3997)
  • Zoology (768)