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Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides
View ORCID ProfileAlice L. B. Pyne, View ORCID ProfileAgnes Noy, Kavit Main, Victor Velasco-Berrelleza, Michael M. Piperakis, Lesley A. Mitchenall, Fiorella M. Cugliandolo, View ORCID ProfileJoseph G. Beton, Clare E.M. Stevenson, View ORCID ProfileBart W. Hoogenboom, Andrew D. Bates, View ORCID ProfileAnthony Maxwell, View ORCID ProfileSarah A. Harris
doi: https://doi.org/10.1101/863423
Alice L. B. Pyne
1Department of Materials Science and Engineering, University of Sheffield, Sheffield S1 3JD, UK
2London Centre for Nanotechnology, University College London, London, WC1H 0AH, UK
Agnes Noy
3Department of Physics, Biological Physical Sciences Institute, University of York, York, UK
Kavit Main
2London Centre for Nanotechnology, University College London, London, WC1H 0AH, UK
4UCL Cancer Institute, University College London, London, WC1E 6DD, UK
Victor Velasco-Berrelleza
3Department of Physics, Biological Physical Sciences Institute, University of York, York, UK
Michael M. Piperakis
5Department of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, UK
Lesley A. Mitchenall
5Department of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, UK
Fiorella M. Cugliandolo
5Department of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, UK
Joseph G. Beton
2London Centre for Nanotechnology, University College London, London, WC1H 0AH, UK
6Department of Crystallography, Institute of Structural and Molecular Biology, Birkbeck, University of London, London WC1E 7HX, UK
Clare E.M. Stevenson
5Department of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, UK
Bart W. Hoogenboom
2London Centre for Nanotechnology, University College London, London, WC1H 0AH, UK
7Department of Physics and Astronomy, University College London, London, WC1E 6BT, UK
Andrew D. Bates
8Institute of Integrative Biology, University of Liverpool, Liverpool L69 7ZB, UK
Anthony Maxwell
5Department of Biological Chemistry, John Innes Centre, Norwich NR4 7UH, UK
Sarah A. Harris
9School of Physics and Astronomy, University of Leeds, Leeds, LS2 9JT, UK
10Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
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Posted January 07, 2021.
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides
Alice L. B. Pyne, Agnes Noy, Kavit Main, Victor Velasco-Berrelleza, Michael M. Piperakis, Lesley A. Mitchenall, Fiorella M. Cugliandolo, Joseph G. Beton, Clare E.M. Stevenson, Bart W. Hoogenboom, Andrew D. Bates, Anthony Maxwell, Sarah A. Harris
bioRxiv 863423; doi: https://doi.org/10.1101/863423
Base-pair resolution analysis of the effect of supercoiling on DNA flexibility and major groove recognition by triplex-forming oligonucleotides
Alice L. B. Pyne, Agnes Noy, Kavit Main, Victor Velasco-Berrelleza, Michael M. Piperakis, Lesley A. Mitchenall, Fiorella M. Cugliandolo, Joseph G. Beton, Clare E.M. Stevenson, Bart W. Hoogenboom, Andrew D. Bates, Anthony Maxwell, Sarah A. Harris
bioRxiv 863423; doi: https://doi.org/10.1101/863423
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