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Quantifying the heterogeneity of macromolecular machines by mass photometry
Adar Sonn-Segev, Katarina Belacic, Tatyana Bodrug, Gavin Young, Ryan T. VanderLinden, Brenda A. Schulman, Johannes Schimpf, Thorsten Friedrich, Phat Vinh Dip, Thomas U. Schwartz, Benedikt Bauer, Jan-Michael Peters, Weston B. Struwe, View ORCID ProfileJustin L. P. Benesch, Nicholas G. Brown, David Haselbach, Philipp Kukura
doi: https://doi.org/10.1101/864553
Adar Sonn-Segev
1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK
Katarina Belacic
2Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-Biocenter 1, 1030 Vienna, Austria
Tatyana Bodrug
3Department of Biochemistry and Biophysics and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA
Gavin Young
1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK
Ryan T. VanderLinden
4Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA Howard Hughes Medical Institute, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA
Brenda A. Schulman
4Department of Structural Biology, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA Howard Hughes Medical Institute, St. Jude Children’s Research Hospital, Memphis, TN 38105, USA
5Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried 82152, Germany
Johannes Schimpf
6Albert-Ludwigs-Universität, Institut für Biochemie, Albertstr. 21, Chemie-Hochhaus, 79104, Freiburg i. Br., Germany
Thorsten Friedrich
6Albert-Ludwigs-Universität, Institut für Biochemie, Albertstr. 21, Chemie-Hochhaus, 79104, Freiburg i. Br., Germany
Phat Vinh Dip
7Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA
Thomas U. Schwartz
7Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA
Benedikt Bauer
2Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-Biocenter 1, 1030 Vienna, Austria
Jan-Michael Peters
2Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-Biocenter 1, 1030 Vienna, Austria
Weston B. Struwe
1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK
Justin L. P. Benesch
1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK
Nicholas G. Brown
8Department of Pharmacology and Lineberger Comprehensive Cancer Center, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
David Haselbach
2Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Campus-Vienna-Biocenter 1, 1030 Vienna, Austria
Philipp Kukura
1Physical and Theoretical Chemistry Laboratory, Department of Chemistry, University of Oxford, South Parks Road, Oxford, OX1 3QZ, UK
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Posted December 04, 2019.
Quantifying the heterogeneity of macromolecular machines by mass photometry
Adar Sonn-Segev, Katarina Belacic, Tatyana Bodrug, Gavin Young, Ryan T. VanderLinden, Brenda A. Schulman, Johannes Schimpf, Thorsten Friedrich, Phat Vinh Dip, Thomas U. Schwartz, Benedikt Bauer, Jan-Michael Peters, Weston B. Struwe, Justin L. P. Benesch, Nicholas G. Brown, David Haselbach, Philipp Kukura
bioRxiv 864553; doi: https://doi.org/10.1101/864553
Quantifying the heterogeneity of macromolecular machines by mass photometry
Adar Sonn-Segev, Katarina Belacic, Tatyana Bodrug, Gavin Young, Ryan T. VanderLinden, Brenda A. Schulman, Johannes Schimpf, Thorsten Friedrich, Phat Vinh Dip, Thomas U. Schwartz, Benedikt Bauer, Jan-Michael Peters, Weston B. Struwe, Justin L. P. Benesch, Nicholas G. Brown, David Haselbach, Philipp Kukura
bioRxiv 864553; doi: https://doi.org/10.1101/864553
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