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DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
View ORCID ProfileZeyad D. Nassar, View ORCID ProfileChui Yan Mah, View ORCID ProfileJonas Dehairs, View ORCID ProfileIngrid J.G. Burvenich, Swati Irani, View ORCID ProfileMargaret M. Centenera, Raj K. Shrestha, View ORCID ProfileMax Moldovan, View ORCID ProfileAnthony S. Don, View ORCID ProfileAndrew M. Scott, View ORCID ProfileLisa G. Horvath, View ORCID ProfileDavid J. Lynn, View ORCID ProfileLuke A. Selth, View ORCID ProfileAndrew J. Hoy, View ORCID ProfileJohannes V. Swinnen, View ORCID ProfileLisa M. Butler
doi: https://doi.org/10.1101/865626
Zeyad D. Nassar
1University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5005, Australia
2South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia
Chui Yan Mah
1University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5005, Australia
2South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia
Jonas Dehairs
3KU Leuven-University of Leuven, LKI-Leuven Cancer Institute, Department of Oncology, Laboratory of Lipid Metabolism and Cancer, Leuven, B-3000, Belgium
Ingrid J.G. Burvenich
4Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, and School of Cancer Medicine, La Trobe University, Melbourne, VIC 3084, Australia
Swati Irani
1University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5005, Australia
2South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia
Margaret M. Centenera
1University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5005, Australia
2South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia
Raj K. Shrestha
5Dame Roma Mitchell Cancer Research Laboratories, University of Adelaide, Adelaide, SA 5005, Australia
Max Moldovan
2South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia
Anthony S. Don
6NHMRC Clinical Trials Centre, and Centenary Institute, The University of Sydney, Camperdown, NSW 2006, Australia
Andrew M. Scott
4Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, and School of Cancer Medicine, La Trobe University, Melbourne, VIC 3084, Australia
Lisa G. Horvath
7Garvan Institute of Medical Research, Darlinghurst, NSW 2010; University of Sydney, Camperdown, NSW 2006; and University of New South Wales, Sydney, NSW 2052, Australia
David J. Lynn
2South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia
8College of Medicine and Public Health, Flinders University, Bedford Park, SA 5042, Australia
Luke A. Selth
1University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5005, Australia
5Dame Roma Mitchell Cancer Research Laboratories, University of Adelaide, Adelaide, SA 5005, Australia
8College of Medicine and Public Health, Flinders University, Bedford Park, SA 5042, Australia
Andrew J. Hoy
9Discipline of Physiology, School of Medical Sciences, Charles Perkins Centre, Faculty of Medicine and Health, The University of Sydney, Camperdown, NSW 2006, Australia
Johannes V. Swinnen
3KU Leuven-University of Leuven, LKI-Leuven Cancer Institute, Department of Oncology, Laboratory of Lipid Metabolism and Cancer, Leuven, B-3000, Belgium
Lisa M. Butler
1University of Adelaide Medical School and Freemasons Foundation Centre for Men’s Health, University of Adelaide, Adelaide, SA 5005, Australia
2South Australian Health and Medical Research Institute, Adelaide, SA 5000, Australia
Article usage
Posted December 06, 2019.
DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
Zeyad D. Nassar, Chui Yan Mah, Jonas Dehairs, Ingrid J.G. Burvenich, Swati Irani, Margaret M. Centenera, Raj K. Shrestha, Max Moldovan, Anthony S. Don, Andrew M. Scott, Lisa G. Horvath, David J. Lynn, Luke A. Selth, Andrew J. Hoy, Johannes V. Swinnen, Lisa M. Butler
bioRxiv 865626; doi: https://doi.org/10.1101/865626
DECR1 is an androgen-repressed survival factor that regulates PUFA oxidation to protect prostate tumor cells from ferroptosis
Zeyad D. Nassar, Chui Yan Mah, Jonas Dehairs, Ingrid J.G. Burvenich, Swati Irani, Margaret M. Centenera, Raj K. Shrestha, Max Moldovan, Anthony S. Don, Andrew M. Scott, Lisa G. Horvath, David J. Lynn, Luke A. Selth, Andrew J. Hoy, Johannes V. Swinnen, Lisa M. Butler
bioRxiv 865626; doi: https://doi.org/10.1101/865626
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