Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

Robin Mesnage; Maxime Teixeira; Daniele Mandrioli; Laura Falcioni; Quinten Raymond Ducarmon; Romy Daniëlle Zwittink; Caroline Amiel; Jean-Michel Panoff; Fiorella Belpoggi; Michael N Antoniou

doi:10.1101/870105

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Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

View ORCID ProfileRobin Mesnage, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Quinten Raymond Ducarmon, Romy Daniëlle Zwittink, Caroline Amiel, Jean-Michel Panoff, View ORCID ProfileFiorella Belpoggi, Michael N Antoniou

doi: https://doi.org/10.1101/870105

Robin Mesnage

1Gene Expression and Therapy Group, King’s College London, Faculty of Life Sciences & Medicine, Department of Medical and Molecular Genetics, Guy’s Hospital, London, SE1 9RT, UK

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ORCID record for Robin Mesnage

Maxime Teixeira

2UR Aliments Bioprocédés Toxicologies Environnements, EA 4651, University of Caen Normandy (UCN), Boulevard Maréchal Juin, CS 14032 Caen Cedex 5, France

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Daniele Mandrioli

3Ramazzini Institute, Via Saliceto, 3, 40010 Bentivoglio, Bologna, Italy

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Laura Falcioni

3Ramazzini Institute, Via Saliceto, 3, 40010 Bentivoglio, Bologna, Italy

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Quinten Raymond Ducarmon

4Center for Microbiome Analyses and Therapeutics, Leiden University Medical Center, Leiden, The Netherlands

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Romy Daniëlle Zwittink

4Center for Microbiome Analyses and Therapeutics, Leiden University Medical Center, Leiden, The Netherlands

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Caroline Amiel

2UR Aliments Bioprocédés Toxicologies Environnements, EA 4651, University of Caen Normandy (UCN), Boulevard Maréchal Juin, CS 14032 Caen Cedex 5, France

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Jean-Michel Panoff

2UR Aliments Bioprocédés Toxicologies Environnements, EA 4651, University of Caen Normandy (UCN), Boulevard Maréchal Juin, CS 14032 Caen Cedex 5, France

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Fiorella Belpoggi

3Ramazzini Institute, Via Saliceto, 3, 40010 Bentivoglio, Bologna, Italy

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Michael N Antoniou

1Gene Expression and Therapy Group, King’s College London, Faculty of Life Sciences & Medicine, Department of Medical and Molecular Genetics, Guy’s Hospital, London, SE1 9RT, UK

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For correspondence: michael.antoniou@kcl.ac.uk

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Posted December 11, 2019.

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Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

Robin Mesnage, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Quinten Raymond Ducarmon, Romy Daniëlle Zwittink, Caroline Amiel, Jean-Michel Panoff, Fiorella Belpoggi, Michael N Antoniou

bioRxiv 870105; doi: https://doi.org/10.1101/870105

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Shotgun metagenomics and metabolomics reveal glyphosate alters the gut microbiome of Sprague-Dawley rats by inhibiting the shikimate pathway

Robin Mesnage, Maxime Teixeira, Daniele Mandrioli, Laura Falcioni, Quinten Raymond Ducarmon, Romy Daniëlle Zwittink, Caroline Amiel, Jean-Michel Panoff, Fiorella Belpoggi, Michael N Antoniou

bioRxiv 870105; doi: https://doi.org/10.1101/870105

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