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Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a novel fibril structure

Kun Zhao, Yaowang Li, Zhenying Liu, Houfang Long, Chunyu Zhao, Feng Luo, Yunpeng Sun, Youqi Tao, Xiao-dong Su, Dan Li, Xueming Li, View ORCID ProfileCong Liu
doi: https://doi.org/10.1101/870758
Kun Zhao
1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
2University of Chinese Academy of Sciences, Beijing 100049, China
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Yaowang Li
3Key Laboratory of Protein Sciences (Tsinghua University), Ministry of Education, School of Life Sciences, Tsinghua University, Beijing 100084, China
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Zhenying Liu
1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
2University of Chinese Academy of Sciences, Beijing 100049, China
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Houfang Long
1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
2University of Chinese Academy of Sciences, Beijing 100049, China
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Chunyu Zhao
1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
2University of Chinese Academy of Sciences, Beijing 100049, China
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Feng Luo
1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
2University of Chinese Academy of Sciences, Beijing 100049, China
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Yunpeng Sun
1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
2University of Chinese Academy of Sciences, Beijing 100049, China
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Youqi Tao
4Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200030, China
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Xiao-dong Su
5State Key Laboratory of Protein and Plant Gene Research, and Biomedical Pioneering Innovation Center (BIOPIC), School of Life Sciences, Peking University, Beijing 100871, China
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Dan Li
4Bio-X Institutes, Shanghai Jiao Tong University, Shanghai 200030, China
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  • For correspondence: liulab@sioc.ac.cn lixueming@tsinghua.edu.cn lidan2017@sjtu.edu.cn
Xueming Li
3Key Laboratory of Protein Sciences (Tsinghua University), Ministry of Education, School of Life Sciences, Tsinghua University, Beijing 100084, China
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  • For correspondence: liulab@sioc.ac.cn lixueming@tsinghua.edu.cn lidan2017@sjtu.edu.cn
Cong Liu
1Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 201210, China
2University of Chinese Academy of Sciences, Beijing 100049, China
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  • ORCID record for Cong Liu
  • For correspondence: liulab@sioc.ac.cn lixueming@tsinghua.edu.cn lidan2017@sjtu.edu.cn
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Posted December 11, 2019.
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Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a novel fibril structure
Kun Zhao, Yaowang Li, Zhenying Liu, Houfang Long, Chunyu Zhao, Feng Luo, Yunpeng Sun, Youqi Tao, Xiao-dong Su, Dan Li, Xueming Li, Cong Liu
bioRxiv 870758; doi: https://doi.org/10.1101/870758
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Parkinson’s disease associated mutation E46K of α-synuclein triggers the formation of a novel fibril structure
Kun Zhao, Yaowang Li, Zhenying Liu, Houfang Long, Chunyu Zhao, Feng Luo, Yunpeng Sun, Youqi Tao, Xiao-dong Su, Dan Li, Xueming Li, Cong Liu
bioRxiv 870758; doi: https://doi.org/10.1101/870758

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