Cluster	ID	Description	GeneRatio	BgRatio	pvalue	p.adjust	qvalue	geneID	Count
hiPSC	hsa03010	Ribosome	110/1294	158/8094	2.07487E-52	6.53584E-50	5.46019E-50	6141/6193/6128/6207/25873/64981/51187/6205/6161/6189/6134/6133/6124/6138/6165/6228/9045/6170/7311/6222/6175/6142/6206/6187/6202/6132/6159/6208/6218/6136/6234/51121/6160/10573/55168/51073/6223/6158/6164/29074/9801/6146/64960/6144/51116/6125/6204/51081/6183/6155/6210/29088/65005/6167/2197/63875/124995/6166/6137/64979/28998/6169/64928/51021/51263/6231/6168/6235/51373/6173/55052/9553/54460/6224/6122/6217/6143/6152/11222/6209/6230/9349/11224/6194/6176/6229/23521/6135/6233/6129/6130/6188/6156/6154/200916/6157/54948/3921/6203/6227/6201/65003/6181/6232/51065/6191/6147/4736/6171/6139	110
hiPSC	hsa05171	Coronavirus disease - COVID-19	89/1294	232/8094	5.39011E-17	8.48943E-15	7.09225E-15	6141/6193/6128/6207/25873/51187/6205/6161/6189/6134/6133/6124/6138/6165/6228/9045/6170/7311/6222/6175/6142/6206/6187/6202/6132/6159/6208/6218/6136/6234/51121/5610/7132/6160/6223/6158/6164/6146/6144/6125/6204/6155/6210/6167/2197/6166/6137/6169/4615/6231/6168/6235/6173/6224/6122/6217/6143/6152/6209/6230/9349/11224/6194/6176/6229/23521/6135/6233/6129/6130/6188/6156/6154/200916/6157/3921/6203/6227/6201/6181/6232/51065/6191/6147/4736/6171/6139/4940/4600	89
hiPSC	hsa05014	Amyotrophic lateral sclerosis	119/1294	364/8094	4.99327E-16	5.24293E-14	4.38006E-14	5217/5714/5693/506/1337/1347/4709/54539/4715/4718/71/4697/203068/4519/4537/4514/4706/5689/637/5685/4710/7132/60/25978/81929/10762/5684/5688/5717/4928/4728/10213/515/4702/10376/9972/4694/5690/1340/1350/10452/11047/4695/23225/29107/1965/517/5879/5695/53371/4716/5694/5686/5868/4726/10280/498/518/522/90550/6396/5692/836/4712/509/5702/10476/7386/220988/4696/54205/7388/5707/9377/1537/29796/4700/4541/4513/4536/4540/4512/4538/4535/4508/1616/4539/23636/7416/4722/4509/2876/5691/23279/55706/79023/581/2521/23511/3710/5216/57122/6428/9631/6432/2882/348995/311/3178/7157/23165/129401/7415/4218/84790/4725/10189/10383/6392	119
hiPSC	hsa05012	Parkinson disease	91/1294	249/8094	8.52652E-16	6.71463E-14	5.60955E-14	5714/5693/506/1337/1347/11315/4709/7295/54539/4715/4718/4697/203068/4519/4537/4514/7311/4706/5689/5685/4710/5684/5688/10105/5717/4728/10213/515/4702/10376/4694/5690/1340/1350/11047/7317/4695/7326/1965/517/5695/4716/5694/5686/4726/498/518/522/90550/5692/836/4712/509/7417/5702/10476/7386/293/4696/54205/7388/5707/9377/1537/29796/4700/7332/4541/4513/4536/4540/4512/4538/4535/4508/1616/4539/7416/4722/4509/5691/292/581/3710/7157/6233/84790/4725/10383/6392/3709	91
hiPSC	hsa03030	DNA replication	27/1294	36/8094	5.42331E-15	3.41669E-13	2.85437E-13	6742/6118/54107/5557/5981/5982/5424/4171/4175/10714/5427/5422/4173/10535/6119/5425/5985/6117/5111/5983/1763/5558/5984/4176/2237/23649/4172	27
hiPSC	hsa03013	RNA transport	72/1294	186/8094	3.35787E-14	1.76288E-12	1.47275E-12	11171/1982/5901/1979/10284/1915/1964/10209/8665/6612/1978/6613/84321/11218/25929/7514/8668/81929/8761/10762/10419/1983/7329/3837/4928/8087/22916/1981/7341/10799/9972/8894/8666/79228/23225/29107/1965/96764/53371/9775/8667/10556/1977/6396/84305/6606/6607/10605/10248/11260/23636/9939/10460/23279/55706/1975/26986/79023/2521/23511/8664/3646/8662/57122/9631/348995/1968/23165/4116/129401/50628/10189	72
hiPSC	hsa05016	Huntington disease	98/1294	306/8094	9.36536E-13	4.21441E-11	3.52081E-11	1175/5714/5693/506/1337/1347/4709/54539/5440/4715/4718/4697/203068/4519/4537/4514/4706/5689/5685/4710/23186/5434/5684/5688/5438/7019/10105/5717/4728/10213/515/4702/10376/4694/5690/1340/1350/11047/4695/517/5695/4716/5694/5686/5433/4726/5331/498/518/522/5692/836/4712/509/7417/5702/10476/5436/7386/293/25942/4696/54205/7388/5707/5441/9377/1537/29796/4700/3066/4541/4513/4536/4540/4512/4538/4535/4508/4539/7416/4722/4509/2876/5691/292/581/2882/3065/7157/148327/84790/4725/6667/10383/6392/6507/6875	98
hiPSC	hsa05020	Prion disease	89/1294	273/8094	3.63991E-12	1.43322E-10	1.19734E-10	5714/5693/506/1337/1347/4709/54539/4715/4718/4697/203068/4519/4537/4514/4706/5689/5685/4710/1459/5684/5688/1457/10105/5717/4728/10213/515/4702/10376/4694/5690/1340/1350/11047/4695/1965/517/5879/5695/4716/5694/5686/4726/498/518/522/90550/5692/836/4712/509/7417/5702/10476/10963/7386/293/4696/54205/7388/5707/9377/1537/29796/4700/4541/4513/4536/4540/4512/4538/4535/4508/4539/7416/4722/4509/5691/292/581/3710/3915/148327/84790/4725/10383/6392/3709/4851	89
hiPSC	hsa04110	Cell cycle	51/1294	124/8094	1.39446E-11	4.88061E-10	4.07737E-10	7531/894/10971/7534/8697/9126/1871/10459/1022/4609/51529/4089/9184/5885/246184/3066/7027/10926/4171/4175/8556/4998/23594/8317/1869/10735/4173/898/595/3065/9088/5111/1875/1019/7157/6502/1111/64682/4085/7465/4176/11200/5591/990/1021/4172/891/890/5347/4088/699	51
hiPSC	hsa00190	Oxidative phosphorylation	52/1294	133/8094	8.46325E-11	2.66592E-09	2.22717E-09	506/1337/1347/4709/54539/4715/4718/4697/4519/4537/4514/4706/4710/4728/515/4702/4694/1340/1350/4695/517/4716/4726/498/518/522/4712/509/10632/10476/7386/4696/7388/9377/1537/29796/4700/4541/4513/4536/4540/4512/4538/4535/4508/4539/4722/4509/9551/4725/521/6392	52
hiPSC	hsa03040	Spliceosome	56/1294	151/8094	1.78588E-10	4.87598E-09	4.0735E-09	4809/5093/9716/84321/51729/10291/6634/23658/1665/8683/22916/51639/10286/6631/6629/51690/6627/84950/9128/51645/9775/10262/11157/3190/6632/10713/83443/220988/10594/10946/23450/55660/9939/9410/6626/2521/3183/4670/84844/6428/6432/6633/6628/25804/3178/6426/6636/6637/27316/6427/4116/27258/10465/6635/10189/57819	56
hiPSC	hsa05010	Alzheimer disease	106/1294	369/8094	1.85752E-10	4.87598E-09	4.0735E-09	5714/5693/506/1337/1347/4709/3845/54539/4715/4718/4697/203068/4519/4537/4514/4706/5689/637/5685/5610/4710/7132/1459/3028/369/5684/5688/1457/10105/5717/4728/2597/10213/515/51107/4702/3416/10376/4694/5690/1340/1350/11047/4695/1965/517/5695/4716/5694/5686/4726/5331/498/518/522/90550/5692/8883/4041/836/8323/4712/509/7417/5702/10476/1499/8772/7386/3667/293/4696/54205/7388/5707/9377/1537/29796/4700/4541/4513/4536/4540/4512/4538/4535/4508/4539/4893/7416/4722/4509/5691/292/3710/348/7855/84790/4725/8322/4023/23401/10383/6392/3709/25825	106
hiPSC	hsa04714	Thermogenesis	71/1294	232/8094	1.24642E-08	3.01054E-07	2.51507E-07	506/1337/1347/4709/3845/54539/4715/4718/65260/71/4697/4519/4537/4514/23028/4706/4710/6602/60/6598/6009/4728/515/4702/51780/4694/1340/1350/4695/517/4716/4726/498/518/522/4712/509/10632/10476/388753/7386/4696/7388/9377/1537/29796/4700/4541/4513/4536/4540/4512/4538/4535/4508/4539/4893/4722/284184/4509/9551/2260/86/6194/148327/1376/4725/521/6599/51287/6392	71
hiPSC	hsa03430	Mismatch repair	16/1294	23/8094	1.33802E-08	3.01054E-07	2.51507E-07	6742/6118/5981/5982/5424/10714/4436/6119/5425/5985/2956/6117/5111/5983/5984/9156	16
hiPSC	hsa03440	Homologous recombination	21/1294	41/8094	1.72508E-07	3.62266E-06	3.02645E-06	79728/5932/29086/6742/6118/11073/5424/10714/6119/5425/7517/6117/675/84142/25788/641/672/8438/83990/580/7516	21
hiPSC	hsa05022	Pathways of neurodegeneration - multiple diseases	117/1294	475/8094	3.53166E-07	6.95295E-06	5.80865E-06	5714/5693/506/1337/1347/11315/4709/3845/54539/4715/4718/4697/203068/4519/4537/4514/7311/4706/5689/637/578/5685/4710/7132/1459/3028/369/25978/5684/5688/1457/10105/5717/4728/10213/515/4702/10376/4694/5690/1340/1350/10452/11047/7317/4695/7326/1965/517/5879/5695/4716/5694/5686/5868/4726/10280/5331/498/518/522/90550/5692/4041/836/8323/4712/509/7417/5702/10476/1499/8772/7386/293/4696/54205/7388/5707/9377/1537/29796/4700/7332/4541/4513/4536/4540/4512/4538/4535/4508/1616/4539/4893/7416/4722/342371/4509/2876/5691/292/581/2521/3710/2882/6233/7855/7415/4218/84790/4725/8322/23401/10383/6392/3709	117
hiPSC	hsa05203	Viral carcinogenesis	60/1294	204/8094	7.74692E-07	1.43546E-05	1.19921E-05	7531/894/3845/10971/7534/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/28973/578/5610/5315/387/87/5879/2958/2960/836/3190/1642/3066/128312/27044/3105/4893/1654/581/5902/898/595/3065/1019/7157/148327/6502/1111/3017/8347/8339/8344/8343/8346/8349/440689/8341/3249/1021/890/3133	60
hiPSC	hsa03050	Proteasome	20/1294	46/8094	8.71065E-06	0.000152436	0.000127349	5714/5693/5689/5685/5684/5688/5717/10213/5690/11047/10197/51371/5695/5694/5686/5692/5702/5707/5691/5720	20
hiPSC	hsa03420	Nucleotide excision repair	19/1294	47/8094	5.03207E-05	0.000815437	0.000681234	1069/6118/5887/1022/54107/1642/5981/5982/5424/10714/5427/6119/5425/5985/6117/5111/5983/1643/5984	19
hiPSC	hsa05322	Systemic lupus erythematosus	40/1294	136/8094	5.29273E-05	0.000815437	0.000681234	55506/3021/3020/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/3015/87/6634/94239/6741/6632/8334/92815/128312/6628/3017/8347/8339/8344/8343/8346/8338/317772/8349/3014/440689/8341/958	40
hiPSC	hsa01230	Biosynthesis of amino acids	26/1294	75/8094	5.43625E-05	0.000815437	0.000681234	26227/445/3417/6472/5831/586/5315/5230/2597/7167/1491/2806/29968/5631/226/22934/5223/102724560/27430/5832/2023/5634/7086/6470/6888/1373	26
hiPSC	hsa03410	Base excision repair	15/1294	33/8094	6.22575E-05	0.000891414	0.000744707	6996/54107/3980/5424/7374/10714/5427/328/143/5425/5111/142/2237/27301/3146	15
hiPSC	hsa03018	RNA degradation	26/1294	79/8094	0.00014588	0.00199792	0.001669106	29883/23016/56915/22803/8761/23658/28960/1656/3313/57472/11340/51690/23404/9125/11157/54512/26986/2023/5393/23019/25804/3329/10950/27258/167227/57819	26
hiPSC	hsa05100	Bacterial invasion of epithelial cells	25/1294	77/8094	0.000247297	0.003211958	0.00268334	867/10097/71/387/60/1399/2335/10459/10095/5879/3688/6464/1499/10801/10093/10552/7414/1495/10163/4735/391/23607/26084/1793/3678	25
hiPSC	hsa04932	Non-alcoholic fatty liver disease	41/1294	150/8094	0.000254917	0.003211958	0.00268334	1337/1347/4709/54539/4715/4718/4697/4519/4514/4706/637/4710/7132/4728/4702/4694/1340/1350/4695/1965/5879/4716/4726/10018/836/4712/7386/3667/4696/54205/7388/9377/1537/29796/4700/4513/4512/4722/581/4725/6392	41
hiPSC	hsa01200	Carbon metabolism	34/1294	118/8094	0.00028957	0.003508254	0.002930872	26227/39/3417/6472/5315/3030/2271/5230/2597/7167/2806/25796/29968/2098/5226/4191/5631/26007/226/1737/22934/5162/5223/128/2023/5634/4329/7086/6470/6888/2731/6392/1373/8801	34
hiPSC	hsa05034	Alcoholism	48/1294	187/8094	0.000398314	0.004646997	0.003882203	55506/3021/3020/3845/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/3015/369/94239/59345/6464/5499/8334/92815/3066/128312/4893/5500/2030/3065/8520/148327/3017/55970/8347/8339/8344/8343/8346/8338/317772/8349/5501/3014/440689/8341	48
hiPSC	hsa03020	RNA polymerase	13/1294	31/8094	0.000508943	0.005725607	0.004783297	5440/30834/5434/5438/221830/84172/64425/5433/5436/5441/51082/51728/10622	13
hiPSC	hsa03008	Ribosome biogenesis in eukaryotes	31/1294	110/8094	0.000797112	0.008658289	0.007233325	4809/5901/55505/10885/1459/6949/7514/22803/1457/23560/84128/55127/51077/10799/29107/134430/92856/84916/28987/55651/10556/10248/55272/3692/51096/2091/54433/1736/29889/23160/26354	31
hiPSC	hsa04613	Neutrophil extracellular trap formation	47/1294	190/8094	0.001084038	0.011291505	0.009433171	55506/3021/3020/71/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/3015/60/94239/10105/5879/5331/7417/293/8334/92815/3066/128312/7416/292/3065/8520/3017/8347/8339/8344/8343/8346/8338/317772/8349/3014/3146/440689/8341	47
hiPSC	hsa03015	mRNA surveillance pathway	28/1294	98/8094	0.001111228	0.011291505	0.009433171	4440/10284/11051/10914/8761/1477/2935/5518/22916/2107/29107/9775/5529/84305/10978/5499/23708/5500/9939/26986/2521/51692/5519/4116/53981/10189/5501/5525	28
hiPSC	hsa04218	Cellular senescence	40/1294	156/8094	0.001200421	0.011816646	0.009871884	894/3845/1978/6009/1871/4609/90550/5928/7417/293/5499/3105/4893/7416/5500/292/10758/3710/4776/1869/898/595/6237/1875/22800/1019/7157/1111/11200/286826/5501/1021/3709/891/2113/890/2308/4088/677/3133	40
hiPSC	hsa00270	Cysteine and methionine metabolism	17/1294	50/8094	0.001327198	0.012668707	0.010583715	26227/6611/586/3945/6723/1491/2806/4357/3939/29968/58478/4191/102724560/27430/1789/4507/191	17
hiPSC	hsa04390	Hippo signaling pathway	40/1294	157/8094	0.001368406	0.01267788	0.010591378	7531/894/10971/7534/71/60/6932/5518/657/3398/84612/4609/4089/7159/26524/5584/8323/1499/5499/92597/5500/25937/1495/2736/595/55233/1490/5519/122786/8994/60485/7855/8322/5501/7003/6788/10413/83439/4088/6657	40
hiPSC	hsa04115	p53 signaling pathway	22/1294	73/8094	0.001733078	0.015597705	0.013030664	9540/894/8795/51246/637/50484/55240/9538/836/54205/581/898/595/900/1643/1019/7057/7157/1111/11200/1021/891	22
hiPSC	hsa04520	Adherens junction	21/1294	71/8094	0.002814452	0.024626458	0.020573482	5881/71/387/1459/87/60/6932/1457/5819/5879/4089/1499/1500/7414/1495/2260/2064/10163/7525/83439/4088	21
hiPSC	hsa05216	Thyroid cancer	13/1294	37/8094	0.00345237	0.029391799	0.024554552	3845/578/6932/8030/4609/7170/1499/4893/581/595/1643/7157/83439	13
hiPSC	hsa05222	Small cell lung cancer	25/1294	92/8094	0.004192198	0.034751118	0.029031845	578/9618/1871/2335/1284/4609/3688/836/54205/581/3655/1869/284217/898/595/1643/1019/3915/7157/6502/3913/1282/10319/1021/1287	25
hiPSC	hsa00620	Pyruvate metabolism	15/1294	47/8094	0.004978153	0.040208158	0.033590775	39/5315/2271/5106/3945/10327/2739/3939/4191/1737/501/5162/128/219/223	15
hiPSC	hsa00240	Pyrimidine metabolism	17/1294	57/8094	0.006241301	0.049150249	0.041061194	56474/50484/7372/1854/1635/7371/79077/4830/790/1723/4833/6240/1841/1503/7298/4860/5167	17
iDAN	hsa04721	Synaptic vesicle cycle	24/540	78/8094	9.62272E-11	2.80021E-08	2.30945E-08	535/6857/4905/22999/5864/6804/6506/6616/6812/10814/9114/155066/26052/534/6844/163/1175/6511/523/533/9296/9550/526/528	24
iDAN	hsa05034	Alcoholism	35/540	187/8094	1.76599E-08	2.56952E-06	2.11919E-06	2775/4915/53358/1813/814/2785/5569/399694/54331/2782/2778/55506/10488/3021/3020/3845/808/2786/2783/627/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/3015	35
iDAN	hsa04360	Axon guidance	34/540	182/8094	2.98228E-08	2.75622E-06	2.27317E-06	2042/816/5362/5063/285220/8829/57144/8503/10505/80031/2044/56896/1020/22885/6092/6585/1630/84628/3897/659/91584/998/2932/1808/5532/1949/2043/103910/1948/3845/5881/5062/1946/5534	34
iDAN	hsa03010	Ribosome	31/540	158/8094	3.78862E-08	2.75622E-06	2.27317E-06	6141/6193/6128/6207/25873/64981/51187/6205/6161/6189/6134/6133/6124/6138/6165/6228/9045/6170/7311/6222/6175/6142/6206/6187/6202/6132/6159/6208/6218/6136/6234	31
iDAN	hsa05110	Vibrio cholerae infection	16/540	50/8094	7.25785E-08	4.22407E-06	3.48377E-06	535/537/9114/155066/534/2778/10945/523/533/9296/11014/9550/526/528/71/30001	16
iDAN	hsa05012	Parkinson disease	37/540	249/8094	2.94533E-06	0.000142849	0.000117813	816/6622/1813/3798/7846/3800/1649/5413/4137/2778/5714/7494/5693/5599/506/1337/1347/11315/4709/514/7295/7280/347733/2774/54539/4715/4718/291/9246/808/4697/203068/4519/51465/4537/4514/7311	37
iDAN	hsa05171	Coronavirus disease - COVID-19	35/540	232/8094	3.86962E-06	0.000160866	0.000132673	8829/8503/5579/5600/6141/6193/6128/5599/6207/25873/51187/6205/6161/6189/6134/6133/6124/6138/6165/6228/9045/6170/7311/6222/6175/6142/6206/6187/6202/6132/6159/6208/6218/6136/6234	35
iDAN	hsa04728	Dopaminergic synapse	24/540	132/8094	5.43322E-06	0.000197634	0.000162997	816/2775/50632/1813/3798/2785/3760/5579/3800/5600/54331/2782/2932/2778/5516/10488/5599/5532/5515/2774/2776/808/2786/2783	24
iDAN	hsa00190	Oxidative phosphorylation	23/540	133/8094	1.99856E-05	0.0006462	0.000532949	535/537/9114/155066/534/506/1337/1347/523/533/4709/514/9296/9550/54539/526/4715/4718/528/4697/4519/4537/4514	23
iDAN	hsa04966	Collecting duct acid secretion	9/540	27/8094	3.87089E-05	0.001126429	0.000929014	535/9114/155066/534/523/9296/9550/526/528	9
iDAN	hsa04724	Glutamatergic synapse	20/540	114/8094	5.58237E-05	0.001476792	0.001217973	2775/6506/1742/50944/2785/3760/2899/5579/54331/2782/2778/157/6511/5532/81539/2776/107/2786/2783/5534	20
iDAN	hsa05022	Pathways of neurodegeneration - multiple diseases	54/540	475/8094	6.35463E-05	0.001540998	0.001270926	816/4741/6804/10297/1742/324/11258/6622/116442/3798/1020/5579/7846/3800/1649/8851/5413/5600/4137/4747/2932/5714/7494/5693/5599/5532/506/1337/1347/11315/4709/9217/514/55860/3845/7280/347733/54539/4715/4718/291/2776/9246/808/627/8325/4697/203068/4519/51465/4537/4514/5534/7311	54
iDAN	hsa04144	Endocytosis	33/540	251/8094	0.000125228	0.002803189	0.002311908	5662/6456/9829/84249/30011/112936/3798/3800/155382/26052/2869/163/51534/1175/23327/998/7251/7879/10890/51100/157/8766/867/5869/60682/9559/57403/10097/29934/10092/378/10193/3305	33
iDAN	hsa04725	Cholinergic synapse	19/540	113/8094	0.000153341	0.003187297	0.002628699	816/43/2775/1137/8503/814/1141/2785/3760/5579/1129/54331/2782/10488/3845/2776/107/2786/2783	19
iDAN	hsa05120	Epithelial cell signaling in Helicobacter pylori infection	14/540	70/8094	0.000174341	0.003382218	0.002789458	535/537/9114/155066/5600/534/998/5599/523/533/9296/9550/526/528	14
iDAN	hsa05132	Salmonella infection	32/540	249/8094	0.00024177	0.004397183	0.003626543	26999/5063/51209/11258/127829/3798/7846/3800/5600/113146/5898/5217/998/7879/5599/5869/103910/8795/83658/2318/55860/7295/7280/347733/10097/6993/10092/302/71/203068/55845/140735	32
iDAN	hsa04723	Retrograde endocannabinoid signaling	22/540	148/8094	0.00030322	0.005190414	0.004280754	2556/22999/2775/1268/2785/3760/5579/5600/54331/2782/5599/4709/54539/4715/4718/2776/107/2562/2786/2783/4697/4537	22
iDAN	hsa05203	Viral carcinogenesis	27/540	204/8094	0.0004576	0.007397867	0.006101334	8503/9114/9519/998/10488/7531/894/3845/10971/7534/7529/7532/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/28973	27
iDAN	hsa04010	MAPK signaling pathway	35/540	294/8094	0.000547867	0.008391011	0.006920421	23542/4254/6196/9175/27092/2254/8649/1846/11221/4915/5801/781/22808/5579/10369/784/1649/1850/5600/4137/777/998/5599/5532/1845/3925/2318/3845/1847/5881/627/5062/1946/3305/5534	35
iDAN	hsa04961	Endocrine and other factor-regulated calcium reabsorption	11/540	53/8094	0.000613634	0.008928373	0.007363606	492/478/6543/5579/6546/26052/163/1175/2778/8766/2776	11
iDAN	hsa04613	Neutrophil extracellular trap formation	25/540	190/8094	0.000802646	0.011122387	0.009173103	1183/8503/5579/5600/55506/3021/3020/291/1184/71/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/3015	25
iDAN	hsa05032	Morphine addiction	15/540	91/8094	0.000919946	0.012168378	0.010035775	2556/2775/9568/2785/3760/5579/54331/2869/2782/2778/157/107/2562/2786/2783	15
iDAN	hsa04145	Phagosome	21/540	152/8094	0.001101848	0.013940773	0.011497545	535/537/8417/23673/948/9114/7846/155066/534/7879/5869/523/533/9296/9550/7280/347733/526/528/71/203068	21
iDAN	hsa05020	Prion disease	32/540	273/8094	0.001217771	0.014765472	0.012177709	8503/4684/4685/3798/7846/3800/1649/5600/2932/5714/5693/10488/5599/5532/506/1337/1347/4709/514/7280/347733/54539/4715/4718/291/4697/203068/4519/4537/4514/3305/5534	32
iDAN	hsa04012	ErbB signaling pathway	14/540	85/8094	0.001359861	0.015828777	0.013054662	816/5063/57144/8503/53358/3084/5579/399694/2932/5599/867/3845/5062/1978	14
iDAN	hsa05100	Bacterial invasion of epithelial cells	13/540	77/8094	0.001583712	0.017725389	0.014618878	1496/55964/8503/23157/53358/399694/26052/998/867/10097/55752/10092/71	13
iDAN	hsa04727	GABAergic synapse	14/540	89/8094	0.002136826	0.021522932	0.017750872	2556/4905/2775/5334/9568/2785/5579/54331/2782/81539/107/2562/2786/2783	14
iDAN	hsa05016	Huntington disease	34/540	306/8094	0.002168636	0.021522932	0.017750872	6804/6506/1742/11258/3798/7846/3800/163/9519/1175/5714/5693/10488/5599/506/1337/1347/4709/514/55860/7280/347733/54539/5440/4715/4718/291/2776/627/4697/203068/4519/4537/4514	34
iDAN	hsa04114	Oocyte meiosis	18/540	129/8094	0.002179627	0.021522932	0.017750872	816/6196/22849/80315/5600/23291/5516/5532/7531/5515/25847/10971/808/107/7534/7529/7532/5534	18
iDAN	hsa04722	Neurotrophin signaling pathway	17/540	119/8094	0.002218859	0.021522932	0.017750872	816/6196/8503/57498/4915/53358/814/5600/399694/998/2932/5599/7531/3845/808/627/9500	17
iDAN	hsa05010	Alzheimer disease	39/540	369/8094	0.002640001	0.024781947	0.020438719	10297/8503/324/6622/3798/1020/7846/3800/1649/8851/4137/2932/5714/7494/5693/5599/5532/506/1337/1347/4709/514/10313/3845/7280/347733/54539/4715/4718/291/2776/808/8325/4697/203068/4519/4537/4514/5534	39
iDAN	hsa04921	Oxytocin signaling pathway	20/540	154/8094	0.003030281	0.027556617	0.022727106	816/27092/2775/814/781/1827/3760/5579/10369/784/57118/2778/5532/3845/2776/808/107/1938/71/5534	20
iDAN	hsa04014	Ras signaling pathway	27/540	232/8094	0.003169047	0.027945233	0.023047615	9846/4254/5063/57144/2254/8503/4915/53358/22808/2785/5579/399694/54331/5898/998/2782/5599/8036/5869/3845/808/2786/5881/2783/627/5062/1946	27
iDAN	hsa05322	Systemic lupus erythematosus	18/540	136/8094	0.003908568	0.033452747	0.027589895	55506/3021/3020/8365/8364/8363/121504/554313/8370/8362/8361/8368/8294/8367/8360/8359/8366/3015	18
iDAN	hsa04720	Long-term potentiation	11/540	67/8094	0.004435548	0.036878414	0.030415187	816/6196/5502/814/5579/5532/3845/2776/808/107/5534	11
iDAN	hsa04713	Circadian entrainment	14/540	97/8094	0.004796785	0.038774009	0.031978564	816/2775/2785/3760/5579/54331/2782/2778/2776/808/107/2786/2783/5592	14
iDAN	hsa04261	Adrenergic signaling in cardiomyocytes	19/540	150/8094	0.005020074	0.039482207	0.032562645	816/492/27092/478/6543/5502/6332/781/10369/784/6546/5600/2778/5516/10488/5515/2776/808/107	19
MDN	hsa04713	Circadian entrainment	36/529	97/8094	8.56683E-19	2.45868E-16	2.01095E-16	8913/10681/117/8911/5332/2784/5582/5593/818/2905/112/23236/2903/6261/9722/3708/4842/816/3760/5579/815/2891/2892/775/2977/2890/114/776/3763/3765/2982/2902/2983/55811/6262/2904	36
MDN	hsa04724	Glutamatergic synapse	34/529	114/8094	1.64939E-14	1.92277E-12	1.57263E-12	10681/5332/2784/2914/5582/27165/2905/22941/9229/112/2918/23236/2903/3708/50944/3760/2899/5579/2891/2892/775/2890/114/776/2898/2915/2897/2902/2917/116443/773/2911/2904/8605	34
MDN	hsa04020	Calcium signaling pathway	51/529	240/8094	2.00987E-14	1.92277E-12	1.57263E-12	5979/8913/57172/8911/4923/5332/5153/5582/1131/3358/818/2905/219931/3360/23236/2903/6261/3708/5027/4842/816/492/2254/6543/4915/5579/1129/6546/777/815/6547/148/4916/774/775/114/491/776/8822/2915/2902/153/27006/9127/84812/51196/773/2911/2277/2066/6262	51
MDN	hsa05033	Nicotine addiction	19/529	40/8094	8.16323E-13	4.77941E-11	3.90908E-11	1141/2561/2905/2565/2903/2558/2557/2566/2891/2892/774/2555/2890/2560/2902/116443/2554/773/2904	19
MDN	hsa04727	GABAergic synapse	28/529	89/8094	8.32651E-13	4.77941E-11	3.90908E-11	10681/2784/5582/2571/27165/2561/2565/9001/112/2558/2557/9568/5579/2566/774/775/2555/114/776/3763/2560/6540/2554/57468/2572/773/6529/10243	28
MDN	hsa04728	Dopaminergic synapse	34/529	132/8094	1.8085E-12	8.65065E-11	7.07535E-11	10681/5332/2784/5582/6531/818/6571/7054/23236/2903/3708/4129/816/50632/1813/3798/3760/5579/5600/815/5522/2891/2892/6323/774/775/2890/776/3763/3765/1644/406/773/2904	34
MDN	hsa05032	Morphine addiction	27/529	91/8094	1.01759E-11	4.17213E-10	3.41238E-10	5141/10681/2784/5153/5582/2561/2565/112/2558/5138/2557/9568/3760/5579/2566/5144/2868/774/2555/114/3763/3765/2560/2554/773/27115/8622	27
MDN	hsa04723	Retrograde endocannabinoid signaling	34/529	148/8094	5.6917E-11	2.0419E-09	1.67006E-09	10681/5332/2784/5582/2561/2565/112/23236/2558/2557/3708/22999/1268/3760/5579/5600/2566/2891/2892/774/775/2555/2890/114/776/3763/3765/2560/2915/2554/4705/773/2911/56901	34
MDN	hsa05031	Amphetamine addiction	21/529	69/8094	1.25404E-09	3.99898E-08	3.27076E-08	5582/6531/818/2905/6571/7054/2903/4129/816/6804/5579/815/2891/2892/775/2890/776/2902/116443/1644/2904	21
MDN	hsa04911	Insulin secretion	23/529	86/8094	3.42104E-09	9.81838E-08	8.03044E-08	117/5332/5582/1131/818/112/9699/23236/3781/816/478/6804/6616/5579/815/11069/775/114/3778/776/27445/6833/6262	23
MDN	hsa04730	Long-term depression	18/529	60/8094	2.49397E-08	6.00425E-07	4.91086E-07	5332/5582/5593/23236/6261/3708/4842/5579/2891/2892/2977/2890/2982/2983/773/2911/3479/8605	18
MDN	hsa04261	Adrenergic signaling in cardiomyocytes	30/529	150/8094	2.51049E-08	6.00425E-07	4.91086E-07	9254/5332/6324/59283/818/783/112/23236/816/492/478/6543/6332/10369/6546/5600/815/5522/11069/6547/148/775/114/491/776/153/55799/6330/785/6262	30
MDN	hsa04725	Cholinergic synapse	25/529	113/8094	4.67418E-08	9.64633E-07	7.88971E-07	1141/10681/3785/5332/2784/5582/1131/818/112/23236/56479/3708/816/43/3760/5579/1129/815/774/775/114/776/3763/3786/773	25
MDN	hsa04921	Oxytocin signaling pathway	30/529	154/8094	4.70552E-08	9.64633E-07	7.88971E-07	9254/57172/5332/51422/5582/7226/59283/818/783/112/23236/6261/3708/816/3760/5579/10369/815/775/2977/114/776/3763/3765/2982/2983/55799/785/6262/8605	30
MDN	hsa04925	Aldosterone synthesis and secretion	23/529	98/8094	5.06159E-08	9.68451E-07	7.92094E-07	8913/57172/8911/5332/5582/6770/818/112/23236/5138/3708/5587/816/492/478/5579/5581/3777/815/775/114/491/776	23
MDN	hsa04726	Serotonergic synapse	25/529	115/8094	6.75892E-08	1.21238E-06	9.91605E-07	10681/5332/2784/5582/1558/2561/3358/3360/6571/23236/260293/3708/4129/3781/3760/5579/774/775/776/3763/3765/2560/1644/773/8605	25
MDN	hsa04929	GnRH secretion	18/529	64/8094	7.59056E-08	1.28147E-06	1.04811E-06	348980/8913/7224/8911/5332/5582/23236/3708/3781/9568/57657/3760/5579/775/776/3763/3765/2100	18
MDN	hsa04720	Long-term potentiation	18/529	67/8094	1.64089E-07	2.61631E-06	2.13987E-06	5332/5582/818/2905/23236/2903/3708/816/5579/815/2891/775/2890/114/2915/2902/2911/2904	18
MDN	hsa04970	Salivary secretion	21/529	93/8094	3.90012E-07	5.89123E-06	4.81843E-06	5332/5582/1131/5593/112/23236/3708/4842/492/478/5579/148/2977/114/3778/491/2982/153/2983/280/279	21
MDN	hsa04024	cAMP signaling pathway	34/529	216/8094	1.26722E-06	1.81846E-05	1.48732E-05	5141/117/1262/10451/818/2905/4886/3360/112/2903/816/492/478/9568/1261/1813/1129/815/11069/5144/2891/2892/775/2890/114/491/776/2902/116443/153/51196/55811/6262/2904	34
MDN	hsa05414	Dilated cardiomyopathy	20/529	96/8094	2.83995E-06	3.7431E-05	3.06148E-05	3675/9254/59283/783/112/7273/6543/10369/6546/8516/6547/775/114/776/153/55799/785/6262/1756/3479	20
MDN	hsa04540	Gap junction	19/529	88/8094	2.86928E-06	3.7431E-05	3.06148E-05	5332/5582/7277/5593/3358/112/23236/51807/3708/1813/5579/2977/114/2982/2915/10381/153/2983/2911	19
MDN	hsa02010	ABC transporters	13/529	45/8094	3.59374E-06	4.48436E-05	3.66775E-05	10347/10060/10057/10058/64137/10350/23460/10349/23461/225/6833/85320/23457	13
MDN	hsa04961	Endocrine and other factor-regulated calcium reabsorption	14/529	53/8094	4.89477E-06	5.85333E-05	4.78743E-05	5332/1759/5582/112/23236/492/478/6543/5579/6546/26052/6547/491/1212	14
MDN	hsa04742	Taste transduction	18/529	86/8094	8.3172E-06	9.22192E-05	7.54259E-05	5332/2784/5153/2914/1131/112/23236/2558/2557/6326/9568/6328/775/2555/114/2554/773/2911	18
MDN	hsa04721	Synaptic vesicle cycle	17/529	78/8094	8.35435E-06	9.22192E-05	7.54259E-05	1759/6531/6571/22999/6804/6616/6812/10814/26052/112755/440279/774/10815/1212/6540/773/6529	17
MDN	hsa04080	Neuroactive ligand-receptor interaction	44/529	341/8094	9.04178E-06	9.61108E-05	7.86089E-05	1141/117/4923/2690/2914/1131/2561/3358/2905/2565/4886/3360/2918/2903/2558/2557/7068/5027/1268/9568/1813/2899/1129/2743/2566/2891/148/4987/2892/2555/2890/2560/2898/2915/2897/2902/2894/2917/116443/2554/153/9127/2911/2904	44
MDN	hsa05410	Hypertrophic cardiomyopathy	18/529	90/8094	1.61624E-05	0.000165665	0.000135497	3675/9254/51422/59283/783/7273/6543/10369/6546/8516/6547/775/776/55799/785/6262/1756/3479	18
MDN	hsa04360	Axon guidance	28/529	182/8094	1.72154E-05	0.000170373	0.000139348	6092/3897/6586/25791/2046/7224/2051/90249/2045/818/2047/816/5362/5063/285220/2044/22885/6585/1630/91584/815/10154/57689/22854/84448/8633/9901/7222	28
MDN	hsa05030	Cocaine addiction	12/529	49/8094	5.30765E-05	0.000507765	0.0004153	6531/2905/6571/7054/2903/4129/1813/2891/2902/116443/1644/2904	12
MDN	hsa04927	Cortisol synthesis and secretion	14/529	65/8094	5.99338E-05	0.000554871	0.000453828	8913/8911/5332/57552/6770/112/23236/3708/3777/775/114/776/3739/8622	14
MDN	hsa05412	Arrhythmogenic right ventricular cardiomyopathy	15/529	77/8094	0.000111857	0.001003216	0.000820528	3675/9254/59283/783/6543/10369/6546/8516/6547/775/776/55799/785/6262/1756	15
MDN	hsa04924	Renin secretion	14/529	69/8094	0.000119234	0.001036976	0.000848141	117/5332/5153/5593/112/23236/3708/775/2977/3778/776/2982/153/2983	14
MDN	hsa05017	Spinocerebellar ataxia	22/529	143/8094	0.000136378	0.001151191	0.000941558	5332/5582/3748/2905/23236/2903/6261/3708/5579/5649/2259/2891/6310/2892/2890/3752/2902/116443/7222/773/2911/2904	22
MDN	hsa04022	cGMP-PKG signaling pathway	24/529	167/8094	0.000202719	0.001662294	0.001359587	8654/5332/5593/112/23236/5138/3708/8471/492/478/6543/5581/6546/6547/148/775/2977/114/3778/491/776/2982/153/2983	24
MDN	hsa04972	Pancreatic secretion	17/529	102/8094	0.000294915	0.002351129	0.001922984	5332/5582/1131/219931/112/23236/3708/5874/492/478/5579/114/3778/491/6262/280/279	17
MDN	hsa04070	Phosphatidylinositol signaling system	16/529	97/8094	0.000497128	0.003856103	0.0031539	1608/5332/8821/5582/64768/1607/1609/9677/23236/3708/8395/9162/5579/8867/84812/51196	16
MDN	hsa04015	Rap1 signaling pathway	27/529	210/8094	0.000526788	0.003978636	0.00325412	260425/5332/5582/10451/112/23236/2903/3937/5587/26037/2254/1268/1813/5579/5600/5909/11069/114/8822/2902/83593/27006/51196/2277/9863/2904/3479	27
MDN	hsa04750	Inflammatory mediator regulation of TRP channels	16/529	98/8094	0.000559139	0.004114693	0.0033654	5332/5582/3358/818/112/23236/3708/816/5579/5581/5600/815/114/55515/3479/8605	16
MDN	hsa05022	Pathways of neurodegeneration - multiple diseases	49/529	475/8094	0.000844349	0.006058207	0.004954998	5413/5332/7473/27019/5582/7277/1131/6531/818/2905/9001/23236/2903/51807/6261/3708/4842/816/4741/6804/3798/5579/5600/4137/815/1768/2891/6310/2892/774/775/2890/776/2915/201625/2902/196385/10381/1770/4744/25981/56171/4705/7222/2911/56901/120892/6262/2904	49
MDN	hsa04270	Vascular smooth muscle contraction	19/529	133/8094	0.000981416	0.00686991	0.005618888	5332/5582/4629/112/23236/79784/3708/5579/5581/148/775/2977/114/3778/776/2982/2983/10267/8605	19
MDN	hsa04971	Gastric acid secretion	13/529	76/8094	0.001159635	0.00792417	0.006481166	5332/5582/1131/818/112/23236/3708/816/478/5579/815/3773/114	13
MDN	hsa04010	MAPK signaling pathway	33/529	294/8094	0.001516981	0.010124968	0.008281195	5801/8913/9254/8569/8911/84867/5582/59283/783/23542/2254/4915/5579/10369/5600/4137/777/5923/51347/774/775/776/8822/27006/2322/7786/773/55799/2277/2066/785/3479/8605	33
MDN	hsa04930	Type II diabetes mellitus	9/529	46/8094	0.002536095	0.016542259	0.013529887	8913/8471/5581/777/774/775/776/6833/773	9
MDN	hsa04974	Protein digestion and absorption	15/529	103/8094	0.00268671	0.01713524	0.014014885	7373/1301/1303/1294/255631/84570/1286/81578/478/6543/6546/6547/1310/340267/1285	15
MDN	hsa04260	Cardiac muscle contraction	13/529	87/8094	0.004025719	0.025112643	0.02053959	9254/59283/783/478/6543/10369/6546/6547/775/776/55799/785/6262	13
MDN	hsa00430	Taurine and hypotaurine metabolism	4/529	11/8094	0.004112523	0.025112643	0.02053959	2571/2686/570/2572	4
MDN	hsa04512	ECM-receptor interaction	13/529	88/8094	0.004450207	0.026608527	0.021763071	3675/158326/255743/3914/3909/1286/22987/9899/5649/8516/7143/7448/1285	13
MDN	hsa04912	GnRH signaling pathway	13/529	93/8094	0.007144713	0.041847606	0.03422709	5332/818/112/23236/3708/816/5579/5600/815/775/114/776/8605	13
MDN	hsa04072	Phospholipase D signaling pathway	18/529	148/8094	0.007684675	0.043652275	0.035703126	1608/5332/1759/2914/1607/1609/112/2918/23236/8395/9162/26052/11069/114/2915/2917/2911/8605	18
MDN	hsa04371	Apelin signaling pathway	17/529	137/8094	0.007757025	0.043652275	0.035703126	10681/5332/51422/2784/112/23236/6261/3708/4842/6543/5581/6546/6547/10891/114/55811/6262	17
MDN	hsa04918	Thyroid hormone synthesis	11/529	75/8094	0.009029883	0.049838007	0.040762427	5332/7849/5582/50506/112/23236/3708/478/5579/114/213	11
Non_MDN	hsa04151	PI3K-Akt signaling pathway	53/601	354/8094	5.08103E-07	0.000154549	0.000133975	3914/1286/4915/8516/7143/27006/2066/9863/3479/1285/10319/5525/2261/1297/5159/7010/1287/3371/3696/4790/3910/7060/6696/5156/3570/5747/596/9134/3908/1902/3685/23678/100533105/3551/2246/6446/7058/2263/7450/7039/1435/285/10110/3566/2065/3693/3791/1298/1942/2788/23239/1299/9586	53
Non_MDN	hsa04512	ECM-receptor interaction	21/601	88/8094	1.19578E-06	0.000154549	0.000133975	3914/1286/8516/7143/1285/10319/1297/1287/960/3371/3696/3910/7060/6696/3908/3685/7058/7450/3693/1298/1299	21
Non_MDN	hsa04510	Focal adhesion	35/601	201/8094	1.51519E-06	0.000154549	0.000133975	3914/1286/5923/8516/7143/3479/1285/10319/1297/5159/1287/3371/4638/3696/3910/7060/6696/5156/64098/5747/596/3725/3908/3685/7409/7058/7450/4660/3693/3791/1793/2318/1298/1299/399694	35
Non_MDN	hsa04010	MAPK signaling pathway	44/601	294/8094	4.96035E-06	0.000379467	0.00032895	4915/5923/51347/776/27006/2066/3479/8605/2261/6788/5159/7010/2122/9252/4790/5924/1843/5156/2353/4296/3725/4217/3304/3303/3551/2246/93589/2263/778/7039/1435/11221/285/4208/8717/7043/929/2065/3791/2318/9448/7040/1942/3306	44
Non_MDN	hsa02010	ABC transporters	12/601	45/8094	7.42578E-05	0.004544579	0.003939573	10060/10350/23460/1244/5243/19/1080/9429/5244/6890/9619/20	12
Non_MDN	hsa04514	Cell adhesion molecules	25/601	149/8094	8.9613E-05	0.004570264	0.003961839	5175/9369/8516/57689/29126/10666/3133/3696/6404/83700/3113/3109/3685/933/4099/4684/4685/84628/90952/23114/6900/152404/24146/3106/5010	25
Non_MDN	hsa01521	EGFR tyrosine kinase inhibitor resistance	15/601	79/8094	0.000600662	0.026257513	0.022761931	9542/3479/2261/5159/558/5156/3570/596/2263/7039/2065/3791/2549/5336/399694	15
Non_MDN	hsa00565	Ether lipid metabolism	11/601	49/8094	0.000745169	0.028502714	0.024708235	8605/8613/54947/9514/8398/5337/122618/5168/8612/11145/7368	11
Non_MDN	hsa05222	Small cell lung cancer	16/601	92/8094	0.001088566	0.037011236	0.032084044	3914/1286/1285/10319/1287/7185/4790/3910/5747/596/9134/3908/3685/3551/6258/2272	16
Non_MDN	hsa05165	Human papillomavirus infection	40/601	331/8094	0.001389752	0.042526417	0.036865006	3914/1286/8516/7143/1285/10319/5525/1297/5159/4600/1287/3133/3371/3696/4790/3910/7060/6696/5747/6773/9134/3908/10379/3685/1739/3551/7058/64398/7450/8717/1740/9368/3693/4851/2308/1298/5663/3106/1299/9586	40
Non_MDN	hsa05414	Dilated cardiomyopathy	16/601	96/8094	0.00173322	0.048215021	0.041796303	8516/776/153/1756/3479/3696/196883/3908/3685/93589/778/6444/111/7043/3693/7040	16
Non_MDN	hsa04014	Ras signaling pathway	30/601	232/8094	0.001917023	0.04888409	0.042376301	4915/5923/27006/3479/8605/2261/5159/7010/4790/5924/5156/9771/8398/5337/3551/2246/2263/8437/7039/1435/9846/285/23179/3791/2549/1942/11145/2788/5336/399694	30