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A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
Steven Watterson, Maria Luisa Guerriero, Mathieu Blanc, Alexander Mazein, Laurence Loewe, Kevin A Robertson, Holly Gibbs, Guanghou Shui, Markus R Wenk, Jane Hillston, Peter Ghazal
doi: https://doi.org/10.1101/000380
Steven Watterson
aDivision of Pathway Medicine, University of Edinburgh Medical, Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, United Kingdom
bCentre for Systems Biology at Edinburgh, CH Waddington Building, The King’s Buildings, West Mains Road, Edinburgh, EH9 3JU, Scotland, United Kingdom
Maria Luisa Guerriero
bCentre for Systems Biology at Edinburgh, CH Waddington Building, The King’s Buildings, West Mains Road, Edinburgh, EH9 3JU, Scotland, United Kingdom
cSchool of Informatics, Informatics Forum, 10 Crichton Street, University of Edinburgh, EH8 9AB, Scotland, United Kingdom
Mathieu Blanc
aDivision of Pathway Medicine, University of Edinburgh Medical, Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, United Kingdom
dCentre for Cardiovascular Science, University of Edinburgh, QMRI, 49 Little France Crescent, EH16 4TJ, Scotland, United Kingdom
Alexander Mazein
aDivision of Pathway Medicine, University of Edinburgh Medical, Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, United Kingdom
bCentre for Systems Biology at Edinburgh, CH Waddington Building, The King’s Buildings, West Mains Road, Edinburgh, EH9 3JU, Scotland, United Kingdom
Laurence Loewe
bCentre for Systems Biology at Edinburgh, CH Waddington Building, The King’s Buildings, West Mains Road, Edinburgh, EH9 3JU, Scotland, United Kingdom
cSchool of Informatics, Informatics Forum, 10 Crichton Street, University of Edinburgh, EH8 9AB, Scotland, United Kingdom
Kevin A Robertson
aDivision of Pathway Medicine, University of Edinburgh Medical, Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, United Kingdom
bCentre for Systems Biology at Edinburgh, CH Waddington Building, The King’s Buildings, West Mains Road, Edinburgh, EH9 3JU, Scotland, United Kingdom
Holly Gibbs
aDivision of Pathway Medicine, University of Edinburgh Medical, Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, United Kingdom
Guanghou Shui
eDepartment of Biochemistry and Department of Biological Sciences, National University of Singapore, Singapore 117597
Markus R Wenk
eDepartment of Biochemistry and Department of Biological Sciences, National University of Singapore, Singapore 117597
Jane Hillston
bCentre for Systems Biology at Edinburgh, CH Waddington Building, The King’s Buildings, West Mains Road, Edinburgh, EH9 3JU, Scotland, United Kingdom
cSchool of Informatics, Informatics Forum, 10 Crichton Street, University of Edinburgh, EH8 9AB, Scotland, United Kingdom
Peter Ghazal
aDivision of Pathway Medicine, University of Edinburgh Medical, Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB, Scotland, United Kingdom
bCentre for Systems Biology at Edinburgh, CH Waddington Building, The King’s Buildings, West Mains Road, Edinburgh, EH9 3JU, Scotland, United Kingdom
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Posted November 14, 2013.
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
Steven Watterson, Maria Luisa Guerriero, Mathieu Blanc, Alexander Mazein, Laurence Loewe, Kevin A Robertson, Holly Gibbs, Guanghou Shui, Markus R Wenk, Jane Hillston, Peter Ghazal
bioRxiv 000380; doi: https://doi.org/10.1101/000380
A model of flux regulation in the cholesterol biosynthesis pathway: Immune mediated graduated flux reduction versus statin-like led stepped flux reduction
Steven Watterson, Maria Luisa Guerriero, Mathieu Blanc, Alexander Mazein, Laurence Loewe, Kevin A Robertson, Holly Gibbs, Guanghou Shui, Markus R Wenk, Jane Hillston, Peter Ghazal
bioRxiv 000380; doi: https://doi.org/10.1101/000380
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