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Genome-wide transcription factor activities are explained by intrinsic conformational dynamics of binding-sites and distal flanking-regions
Munazah Andrabi, Andrew Paul Hutchins, Diego Miranda-Saavedra, Hidetoshi Kono, Ruth Nussinov, Kenji Mizuguchi, Shandar Ahmad
doi: https://doi.org/10.1101/020602
Munazah Andrabi
1National Institutes of Biomedical Innovation Health and Nutrition, 7-6-8, Saito-Asagi, Ibaraki, Osaka 5670085, Japan
Andrew Paul Hutchins
3Key Laboratory of Regenerative Biology, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Science, 190 Kai Yuan Avenue, Guangzhou, 510530, China
Diego Miranda-Saavedra
4World Premier International (WPI) Immunology Frontier Research Center (IFReC), Osaka University, 3-1 Yamadaoka, Suita 565-0871, Osaka, Japan
5Centro de Biología Molecular Severo Ochoa, CSIC/Universidad Autónoma de Madrid, 28049 Madrid, Spain
Hidetoshi Kono
6Molecular Modeling and Simulation (MMS) Group, Japan Atomic Energy Agency (JAEA), 8-1-7, Umemidai, Kizugawa, Kyoto 619-0215 Japan
Ruth Nussinov
7National Cancer Institute, Cancer and Inflammation Program, Leidos Biomedical Research, Inc. Frederick, Maryland, USA
8Department of biochemistry and Human Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Kenji Mizuguchi
1National Institutes of Biomedical Innovation Health and Nutrition, 7-6-8, Saito-Asagi, Ibaraki, Osaka 5670085, Japan
2Graduate School of Frontier Bioscience, Osaka University, Osaka, Japan
Shandar Ahmad
1National Institutes of Biomedical Innovation Health and Nutrition, 7-6-8, Saito-Asagi, Ibaraki, Osaka 5670085, Japan
2Graduate School of Frontier Bioscience, Osaka University, Osaka, Japan
Article usage
Posted June 09, 2015.
Genome-wide transcription factor activities are explained by intrinsic conformational dynamics of binding-sites and distal flanking-regions
Munazah Andrabi, Andrew Paul Hutchins, Diego Miranda-Saavedra, Hidetoshi Kono, Ruth Nussinov, Kenji Mizuguchi, Shandar Ahmad
bioRxiv 020602; doi: https://doi.org/10.1101/020602
Genome-wide transcription factor activities are explained by intrinsic conformational dynamics of binding-sites and distal flanking-regions
Munazah Andrabi, Andrew Paul Hutchins, Diego Miranda-Saavedra, Hidetoshi Kono, Ruth Nussinov, Kenji Mizuguchi, Shandar Ahmad
bioRxiv 020602; doi: https://doi.org/10.1101/020602
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