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SCT promoter methylation is a highly discriminative biomarker for lung and many other cancers
Adwait Sathe, Yu-An Zhang, Xiaotu Ma, Pradipta Ray, Daniela Cadinu, Yi-Wei Wang, Xiao Yao, Xiaoyun Liu, Hao Tang, Yunfei Wang, Ying Huang, Changning Liu, Jin Gu, Martin Akerman, Yifan Mo, Chao Cheng, Zhenyu Xuan, Lei Chen, Guanghua Xiao, Yang Xie, Luc Girard, Hongyang Wang, Stephen Lam, Ignacio I Wistuba, Li Zhang, Adi F Gazdar, Michael Q Zhang
doi: https://doi.org/10.1101/018515
Adwait Sathe
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Yu-An Zhang
2The Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Xiaotu Ma
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Pradipta Ray
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Daniela Cadinu
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Yi-Wei Wang
2The Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Xiao Yao
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Xiaoyun Liu
2The Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Hao Tang
3Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Yunfei Wang
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Ying Huang
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Changning Liu
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Jin Gu
4Division of Bioinformatics, Center for Synthetic and Systems Biology, TNLIST, Tsinghua University, Beijing 100084, China
Martin Akerman
5Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
Yifan Mo
5Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA
Chao Cheng
6Department of Genetics, Geisel School of Medicine at Dartmouth, Hanover, NH, USA
Zhenyu Xuan
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Lei Chen
7Laboratory of Signal Transduction, Eastern Hepatobiliary Surgery Hospital, SMMU, Shanghai 200438, China
Guanghua Xiao
3Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Yang Xie
3Department of Clinical Science, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Luc Girard
2The Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Hongyang Wang
7Laboratory of Signal Transduction, Eastern Hepatobiliary Surgery Hospital, SMMU, Shanghai 200438, China
Stephen Lam
8BC Cancer Research Center, BC Cancer Agency, Vancouver, BC V521L3, Canada
Ignacio I Wistuba
9Department of Translational Molecular Pathology, Thoracic/Head and Neck Medical Oncology, The University of Texas, MD Anderson Cancer Center, Houston TX 77030, USA
Li Zhang
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
Adi F Gazdar
2The Hamon Center for Therapeutic Oncology Research and Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
Michael Q Zhang
1Center for Systems Biology, Department of Molecular and Cell Biology, The University of Texas at Dallas, 800 W Campbell Rd., Richardson, TX, 75080, USA
4Division of Bioinformatics, Center for Synthetic and Systems Biology, TNLIST, Tsinghua University, Beijing 100084, China
Article usage
Posted August 05, 2015.
SCT promoter methylation is a highly discriminative biomarker for lung and many other cancers
Adwait Sathe, Yu-An Zhang, Xiaotu Ma, Pradipta Ray, Daniela Cadinu, Yi-Wei Wang, Xiao Yao, Xiaoyun Liu, Hao Tang, Yunfei Wang, Ying Huang, Changning Liu, Jin Gu, Martin Akerman, Yifan Mo, Chao Cheng, Zhenyu Xuan, Lei Chen, Guanghua Xiao, Yang Xie, Luc Girard, Hongyang Wang, Stephen Lam, Ignacio I Wistuba, Li Zhang, Adi F Gazdar, Michael Q Zhang
bioRxiv 018515; doi: https://doi.org/10.1101/018515
SCT promoter methylation is a highly discriminative biomarker for lung and many other cancers
Adwait Sathe, Yu-An Zhang, Xiaotu Ma, Pradipta Ray, Daniela Cadinu, Yi-Wei Wang, Xiao Yao, Xiaoyun Liu, Hao Tang, Yunfei Wang, Ying Huang, Changning Liu, Jin Gu, Martin Akerman, Yifan Mo, Chao Cheng, Zhenyu Xuan, Lei Chen, Guanghua Xiao, Yang Xie, Luc Girard, Hongyang Wang, Stephen Lam, Ignacio I Wistuba, Li Zhang, Adi F Gazdar, Michael Q Zhang
bioRxiv 018515; doi: https://doi.org/10.1101/018515
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