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Discovery of a persistent Zika virus lineage in Bahia, Brazil

Samia Naccache, Julien Theze, Silvia I Sardi, Sneha Somasekar, Alexander L Greninger, Antonio C Bandeira, Gubio S Campos, Laura B Tauro, Nuno R Faria, Oliver G Pybus, View ORCID ProfileCharles Y Chiu
doi: https://doi.org/10.1101/049916
Samia Naccache
University of California, San Francisco;
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Julien Theze
University of Oxford;
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Silvia I Sardi
Federal Univeresity of Bahia;
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Sneha Somasekar
University of California, San Francisco;
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Alexander L Greninger
University of Washington;
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Antonio C Bandeira
Alianca Hospital, Salvador, Bahia, Brazil;
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Gubio S Campos
Federal University of Bahia;
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Laura B Tauro
Center of Research Gonzalo Moniz, Foundation Fiocruz;
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Nuno R Faria
Evandro Chagas Institute
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Oliver G Pybus
University of Oxford;
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Charles Y Chiu
University of California, San Francisco;
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  • ORCID record for Charles Y Chiu
  • For correspondence: charles.chiu@ucsf.edu
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Abstract

Metagenomic next-generation sequencing coupled with capture probe enrichment was used to recover 11 whole and partial Zika virus (ZIKV) genomes from patients in Bahia, Brazil from April 2015 to January 2016, where the majority of suspected Brazilian ZIKV cases have been reported. Phylogenetic reconstructions and molecular clock analyses using the newly generated data uncovered the existence of a Bahia-specific ZIKV lineage sharing a common ancestor in mid-2014, indicating sustained circulation of this strain in Bahia since that date.

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The copyright holder for this preprint is the author/funder. It is made available under a CC-BY-NC-ND 4.0 International license.
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  • Posted April 24, 2016.

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Discovery of a persistent Zika virus lineage in Bahia, Brazil
Samia Naccache, Julien Theze, Silvia I Sardi, Sneha Somasekar, Alexander L Greninger, Antonio C Bandeira, Gubio S Campos, Laura B Tauro, Nuno R Faria, Oliver G Pybus, Charles Y Chiu
bioRxiv 049916; doi: https://doi.org/10.1101/049916
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Discovery of a persistent Zika virus lineage in Bahia, Brazil
Samia Naccache, Julien Theze, Silvia I Sardi, Sneha Somasekar, Alexander L Greninger, Antonio C Bandeira, Gubio S Campos, Laura B Tauro, Nuno R Faria, Oliver G Pybus, Charles Y Chiu
bioRxiv 049916; doi: https://doi.org/10.1101/049916

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