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Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7
Yang Luo, Katrina M. de Lange, Luke Jostins, Loukas Moutsianas, Joshua Randall, Nicholas A. Kennedy, Christopher A. Lamb, Shane McCarthy, Tariq Ahmad, Cathryn Edwards, Eva Goncalves Serra, Ailsa Hart, Chris Hawkey, John C. Mansfield, Craig Mowat, William G. Newman, Sam Nichols, Martin Pollard, Jack Satsangi, Alison Simmons, Mark Tremelling, Holm Uhlig, David C. Wilson, James C. Lee, Natalie J. Prescott, Charlie W. Lees, Christopher G. Mathew, Miles Parkes, Jeffrey C. Barrett, Carl A. Anderson
doi: https://doi.org/10.1101/058347
Yang Luo
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
2Division of Genetics and Rheumatology, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USA
3Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA, USA
Katrina M. de Lange
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Luke Jostins
4Wellcome Trust Centre for Human Genetics, University of Oxford, Headington, UK
5Christ Church, University of Oxford St Aldates, UK
Loukas Moutsianas
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Joshua Randall
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Nicholas A. Kennedy
6Precision Medicine Exeter, University of Exeter, Exeter, UK
7IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK
Christopher A. Lamb
8Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne
Shane McCarthy
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Tariq Ahmad
6Precision Medicine Exeter, University of Exeter, Exeter, UK
7IBD Pharmacogenetics, Royal Devon and Exeter Foundation Trust, Exeter, UK
Cathryn Edwards
9Department of Gastroenterology, Torbay Hospital, Torbay, Devon, UK
Eva Goncalves Serra
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Ailsa Hart
10Department of Medicine, St Mark’s Hospital, Harrow, Middlesex, UK
Chris Hawkey
11Nottingham Digestive Diseases Centre, Queens Medical Centre, Nottingham, UK
John C. Mansfield
12Institute of Human Genetics, Newcastle University, Newcastle upon Tyne, UK
Craig Mowat
13Department of Medicine, Ninewells Hospital and Medical School, Dundee, UK
William G. Newman
14Genetic Medicine, Manchester Academic Health Science Centre, Manchester, UK
15The Manchester Centre for Genomic Medicine, University of Manchester, Manchester, UK
Sam Nichols
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Martin Pollard
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Jack Satsangi
16Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK
Alison Simmons
17Translational Gastroenterology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK
18Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, UK
Mark Tremelling
19Gastroenterology & General Medicine, Norfolk and Norwich University Hospital, Norwich, UK
Holm Uhlig
20Translational Gastroenterology Unit and the Department of Paediatrics, University of Oxford, Oxford, United Kingdom
David C. Wilson
21Paediatric Gastroenterology and Nutrition, Royal Hospital for Sick Children, Edinburgh, UK
22Child Life and Health, University of Edinburgh, Edinburgh, Scotland, UK
James C. Lee
23Inflammatory Bowel Disease Research Group, Addenbrooke’s Hospital, Cambridge, UK
Natalie J. Prescott
24Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King’s College London, Guy’s Hospital, London, UK
Charlie W. Lees
16Gastrointestinal Unit, Wester General Hospital University of Edinburgh, Edinburgh, UK
Christopher G. Mathew
24Department of Medical and Molecular Genetics, Faculty of Life Science and Medicine, King’s College London, Guy’s Hospital, London, UK
25Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences, University of Witwatersrand, South Africa.
Miles Parkes
23Inflammatory Bowel Disease Research Group, Addenbrooke’s Hospital, Cambridge, UK
Jeffrey C. Barrett
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Carl A. Anderson
1Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK
Article usage
Posted June 11, 2016.
Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7
Yang Luo, Katrina M. de Lange, Luke Jostins, Loukas Moutsianas, Joshua Randall, Nicholas A. Kennedy, Christopher A. Lamb, Shane McCarthy, Tariq Ahmad, Cathryn Edwards, Eva Goncalves Serra, Ailsa Hart, Chris Hawkey, John C. Mansfield, Craig Mowat, William G. Newman, Sam Nichols, Martin Pollard, Jack Satsangi, Alison Simmons, Mark Tremelling, Holm Uhlig, David C. Wilson, James C. Lee, Natalie J. Prescott, Charlie W. Lees, Christopher G. Mathew, Miles Parkes, Jeffrey C. Barrett, Carl A. Anderson
bioRxiv 058347; doi: https://doi.org/10.1101/058347
Exploring the genetic architecture of inflammatory bowel disease by whole genome sequencing identifies association at ADCY7
Yang Luo, Katrina M. de Lange, Luke Jostins, Loukas Moutsianas, Joshua Randall, Nicholas A. Kennedy, Christopher A. Lamb, Shane McCarthy, Tariq Ahmad, Cathryn Edwards, Eva Goncalves Serra, Ailsa Hart, Chris Hawkey, John C. Mansfield, Craig Mowat, William G. Newman, Sam Nichols, Martin Pollard, Jack Satsangi, Alison Simmons, Mark Tremelling, Holm Uhlig, David C. Wilson, James C. Lee, Natalie J. Prescott, Charlie W. Lees, Christopher G. Mathew, Miles Parkes, Jeffrey C. Barrett, Carl A. Anderson
bioRxiv 058347; doi: https://doi.org/10.1101/058347
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