Skip to main content
bioRxiv
  • Home
  • About
  • Submit
  • ALERTS / RSS
Advanced Search
New Results

Comparative Genomic Evidence for Self-Domestication in Homo sapiens

Constantina Theofanopoulou, Simone Gastaldon, Thomas O'Rourke, Bridget D Samuels, Angela Messner, Pedro Tiago Martins, Francesco Delogu, Saleh Alamri, Cedric Boeckx
doi: https://doi.org/10.1101/125799
Constantina Theofanopoulou
Universitat de Barcelona;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Simone Gastaldon
Universitat de Barcelona;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas O'Rourke
Universitat de Barcelona;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Bridget D Samuels
University of Southern California;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Angela Messner
Universitat de Barcelona;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pedro Tiago Martins
Universitat de Barcelona;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francesco Delogu
Norwegian University of Life Sciences;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Saleh Alamri
Universitat de Barcelona;
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cedric Boeckx
Universitat de Barcelona/ICREA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: cedric.boeckx@ub.edu
  • Abstract
  • Info/History
  • Metrics
  • Data Supplements
  • Preview PDF
Loading

Abstract

This study identifies and analyzes statistically significant overlaps between selective sweep screens in anatomically modern humans and several domesticated species. The results obtained suggest that (paleo-)genomic data can be exploited to complement the fossil record and support the idea of self-domestication in Homo sapiens, a process that likely intensified as our species populated its niche. Our analysis lends support to attempts to capture the “domestication syndrome” in terms of alterations to certain signaling pathways and cell lineages, such as the neural crest.

Copyright 
The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Back to top
PreviousNext
  • Posted April 9, 2017.

Download PDF

Email

Thank you for your interest in spreading the word about bioRxiv.

NOTE: Your email address is requested solely to identify you as the sender of this article.

Enter multiple addresses on separate lines or separate them with commas.
Comparative Genomic Evidence for Self-Domestication in Homo sapiens
(Your Name) has forwarded a page to you from bioRxiv
(Your Name) thought you would like to see this page from the bioRxiv website.
Share
Comparative Genomic Evidence for Self-Domestication in Homo sapiens
Constantina Theofanopoulou, Simone Gastaldon, Thomas O'Rourke, Bridget D Samuels, Angela Messner, Pedro Tiago Martins, Francesco Delogu, Saleh Alamri, Cedric Boeckx
bioRxiv 125799; doi: https://doi.org/10.1101/125799
Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
Citation Tools
Comparative Genomic Evidence for Self-Domestication in Homo sapiens
Constantina Theofanopoulou, Simone Gastaldon, Thomas O'Rourke, Bridget D Samuels, Angela Messner, Pedro Tiago Martins, Francesco Delogu, Saleh Alamri, Cedric Boeckx
bioRxiv 125799; doi: https://doi.org/10.1101/125799

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Subject Area

  • Genomics
Subject Areas
All Articles
  • Animal Behavior and Cognition (814)
  • Biochemistry (1127)
  • Bioengineering (718)
  • Bioinformatics (5722)
  • Biophysics (1946)
  • Cancer Biology (1382)
  • Cell Biology (1961)
  • Clinical Trials (71)
  • Developmental Biology (1340)
  • Ecology (2048)
  • Epidemiology (1096)
  • Evolutionary Biology (4335)
  • Genetics (3045)
  • Genomics (3926)
  • Immunology (838)
  • Microbiology (3291)
  • Molecular Biology (1220)
  • Neuroscience (8388)
  • Paleontology (62)
  • Pathology (169)
  • Pharmacology and Toxicology (304)
  • Physiology (401)
  • Plant Biology (1141)
  • Scientific Communication and Education (318)
  • Synthetic Biology (469)
  • Systems Biology (1598)
  • Zoology (210)