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Glucose limitation in Lactococcus shapes a single-peaked fitness landscape exposing membrane occupancy as a constraint
Claire E. Price, Filipe Branco dos Santos, Anne Hesseling, Jaakko J. Uusitalo, Herwig Bachmann, Vera Benavente, Anisha Goel, Jan Berkhout, Frank J. Bruggeman, Siewert-Jan Marrink, Manolo Montalban-Lopez, Anne de Jong, View ORCID ProfileJan Kok, View ORCID ProfileDouwe Molenaar, Bert Poolman, Bas Teusink, View ORCID ProfileOscar P. Kuipers
doi: https://doi.org/10.1101/147926
Claire E. Price
aMolecular Genetics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
bDepartment of Biochemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands
cKluyver Center for Genomics of Industrial Fermentations/NCSB, Julianalaan 67, 2628 BC Delft, The Netherlands
Filipe Branco dos Santos
cKluyver Center for Genomics of Industrial Fermentations/NCSB, Julianalaan 67, 2628 BC Delft, The Netherlands
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
eMolecular Microbial Physiology Group, Faculty of Life Sciences, Swammerdam Institute of Life Sciences, University of Amsterdam, Science Park 904, Amsterdam 1098 XH, Netherlands
Anne Hesseling
aMolecular Genetics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
Jaakko J. Uusitalo
fMolecular Dynamics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
Herwig Bachmann
cKluyver Center for Genomics of Industrial Fermentations/NCSB, Julianalaan 67, 2628 BC Delft, The Netherlands
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
Vera Benavente
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
Anisha Goel
cKluyver Center for Genomics of Industrial Fermentations/NCSB, Julianalaan 67, 2628 BC Delft, The Netherlands
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
Jan Berkhout
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
Frank J. Bruggeman
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
Siewert-Jan Marrink
fMolecular Dynamics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
Manolo Montalban-Lopez
aMolecular Genetics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
Anne de Jong
aMolecular Genetics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
Jan Kok
aMolecular Genetics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
Douwe Molenaar
cKluyver Center for Genomics of Industrial Fermentations/NCSB, Julianalaan 67, 2628 BC Delft, The Netherlands
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
Bert Poolman
bDepartment of Biochemistry, University of Groningen, Nijenborgh 4, 9747 AG Groningen, the Netherlands
Bas Teusink
cKluyver Center for Genomics of Industrial Fermentations/NCSB, Julianalaan 67, 2628 BC Delft, The Netherlands
dSystems Bioinformatics, Faculty of Earth and Life Sciences, VU University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands
Oscar P. Kuipers
aMolecular Genetics group, University of Groningen, Nijenborgh 7, 9747 AG Groningen, the Netherlands
cKluyver Center for Genomics of Industrial Fermentations/NCSB, Julianalaan 67, 2628 BC Delft, The Netherlands
Article usage
Posted June 08, 2017.
Glucose limitation in Lactococcus shapes a single-peaked fitness landscape exposing membrane occupancy as a constraint
Claire E. Price, Filipe Branco dos Santos, Anne Hesseling, Jaakko J. Uusitalo, Herwig Bachmann, Vera Benavente, Anisha Goel, Jan Berkhout, Frank J. Bruggeman, Siewert-Jan Marrink, Manolo Montalban-Lopez, Anne de Jong, Jan Kok, Douwe Molenaar, Bert Poolman, Bas Teusink, Oscar P. Kuipers
bioRxiv 147926; doi: https://doi.org/10.1101/147926
Glucose limitation in Lactococcus shapes a single-peaked fitness landscape exposing membrane occupancy as a constraint
Claire E. Price, Filipe Branco dos Santos, Anne Hesseling, Jaakko J. Uusitalo, Herwig Bachmann, Vera Benavente, Anisha Goel, Jan Berkhout, Frank J. Bruggeman, Siewert-Jan Marrink, Manolo Montalban-Lopez, Anne de Jong, Jan Kok, Douwe Molenaar, Bert Poolman, Bas Teusink, Oscar P. Kuipers
bioRxiv 147926; doi: https://doi.org/10.1101/147926
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