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Kinome rewiring reveals AURKA is a molecular barrier to the efficacy of PI3K/mTOR-pathway inhibitors in breast cancer
Hayley J Donnella, View ORCID ProfileJames T Webber, Rebecca S Levin, Roman Camarda, Olga Momcilovic, Nora Bayani, James Korkola, Kevan M Shokat, Andrei Goga, John Gordan, View ORCID ProfileSourav Bandyopadhyay
doi: https://doi.org/10.1101/158295
Hayley J Donnella
1University of California, San Francisco. Department of Bioengineering and Therapeutic Sciences, San Francisco, CA 94148.
James T Webber
1University of California, San Francisco. Department of Bioengineering and Therapeutic Sciences, San Francisco, CA 94148.
Rebecca S Levin
2University of California, San Francisco. Department of Cellular and Molecular Pharmacology, San Francisco, CA 94148.
Roman Camarda
3University of California, San Francisco. Department of Medicine, San Francisco, CA 94148.
Olga Momcilovic
3University of California, San Francisco. Department of Medicine, San Francisco, CA 94148.
Nora Bayani
5Oregon Health and Sciences University. Center for Spatial Systems Biology, Portland, OR 97239
James Korkola
5Oregon Health and Sciences University. Center for Spatial Systems Biology, Portland, OR 97239
Kevan M Shokat
2University of California, San Francisco. Department of Cellular and Molecular Pharmacology, San Francisco, CA 94148.
3University of California, San Francisco. Department of Medicine, San Francisco, CA 94148.
Andrei Goga
3University of California, San Francisco. Department of Medicine, San Francisco, CA 94148.
John Gordan
3University of California, San Francisco. Department of Medicine, San Francisco, CA 94148.
Sourav Bandyopadhyay
1University of California, San Francisco. Department of Bioengineering and Therapeutic Sciences, San Francisco, CA 94148.
Article usage
Posted June 30, 2017.
Kinome rewiring reveals AURKA is a molecular barrier to the efficacy of PI3K/mTOR-pathway inhibitors in breast cancer
Hayley J Donnella, James T Webber, Rebecca S Levin, Roman Camarda, Olga Momcilovic, Nora Bayani, James Korkola, Kevan M Shokat, Andrei Goga, John Gordan, Sourav Bandyopadhyay
bioRxiv 158295; doi: https://doi.org/10.1101/158295
Kinome rewiring reveals AURKA is a molecular barrier to the efficacy of PI3K/mTOR-pathway inhibitors in breast cancer
Hayley J Donnella, James T Webber, Rebecca S Levin, Roman Camarda, Olga Momcilovic, Nora Bayani, James Korkola, Kevan M Shokat, Andrei Goga, John Gordan, Sourav Bandyopadhyay
bioRxiv 158295; doi: https://doi.org/10.1101/158295
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