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Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line

Maria Nattestad, Sara Goodwin, Karen Ng, Timour Baslan, Fritz J. Sedlazeck, Philipp Rescheneder, Tyler Garvin, Han Fang, James Gurtowski, Elizabeth Hutton, Elizabeth Tseng, Chen-Shan Chin, Timothy Beck, Yogi Sundaravadanam, Melissa Kramer, Eric Antoniou, John D. McPherson, James Hicks, William Richard McCombie, Michael C. Schatz
doi: https://doi.org/10.1101/174938
Maria Nattestad
Cold Spring Harbor Laboratory;
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Sara Goodwin
Cold Spring Harbor Laboratory;
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Karen Ng
Ontario Institute for Cancer Research;
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Timour Baslan
Memorial Sloan Kettering Cancer Center;
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Fritz J. Sedlazeck
Baylor College of Medicine;
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Philipp Rescheneder
University of Vienna;
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Tyler Garvin
Cold Spring Harbor Laboratory;
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Han Fang
Cold Spring Harbor Laboratory;
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James Gurtowski
Cold Spring Harbor Laboratory;
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Elizabeth Hutton
Cold Spring Harbor Laboratory;
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Elizabeth Tseng
Pacific Biosciences;
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Chen-Shan Chin
Pacific Biosciences;
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Timothy Beck
Ontario Institute for Cancer Research;
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Yogi Sundaravadanam
Ontario Institute for Cancer Research;
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Melissa Kramer
Cold Spring Harbor Laboratory;
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Eric Antoniou
Cold Spring Harbor Laboratory;
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John D. McPherson
UC Davis Comprehensive Cancer Center;
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James Hicks
Cold Spring Harbor Laboratory;
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William Richard McCombie
Cold Spring Harbor Laboratory;
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Michael C. Schatz
Johns Hopkins University
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  • For correspondence: mschatz@cs.jhu.edu
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Article Information

doi 
https://doi.org/10.1101/174938
History 
  • August 10, 2017.
Copyright 
The copyright holder for this preprint is the author/funder. All rights reserved. No reuse allowed without permission.

Author Information

  1. Maria Nattestad1 (mnattest{at}cshl.edu),
  2. Sara Goodwin1,
  3. Karen Ng2,
  4. Timour Baslan3,
  5. Fritz J. Sedlazeck4,
  6. Philipp Rescheneder5,
  7. Tyler Garvin1,
  8. Han Fang1,
  9. James Gurtowski1,
  10. Elizabeth Hutton1,
  11. Elizabeth Tseng6,
  12. Chen-Shan Chin6,
  13. Timothy Beck2,
  14. Yogi Sundaravadanam2,
  15. Melissa Kramer1,
  16. Eric Antoniou1,
  17. John D. McPherson7,
  18. James Hicks1,
  19. William Richard McCombie1 and
  20. Michael C. Schatz8,9 (mschatz{at}cs.jhu.edu)
  1. 1 Cold Spring Harbor Laboratory;
  2. 2 Ontario Institute for Cancer Research;
  3. 3 Memorial Sloan Kettering Cancer Center;
  4. 4 Baylor College of Medicine;
  5. 5 University of Vienna;
  6. 6 Pacific Biosciences;
  7. 7 UC Davis Comprehensive Cancer Center;
  8. 8 Johns Hopkins University
  1. ↵* Corresponding author; email: mschatz{at}cs.jhu.edu
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  • Posted August 10, 2017.

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Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line
Maria Nattestad, Sara Goodwin, Karen Ng, Timour Baslan, Fritz J. Sedlazeck, Philipp Rescheneder, Tyler Garvin, Han Fang, James Gurtowski, Elizabeth Hutton, Elizabeth Tseng, Chen-Shan Chin, Timothy Beck, Yogi Sundaravadanam, Melissa Kramer, Eric Antoniou, John D. McPherson, James Hicks, William Richard McCombie, Michael C. Schatz
bioRxiv 174938; doi: https://doi.org/10.1101/174938
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Complex rearrangements and oncogene amplifications revealed by long-read DNA and RNA sequencing of a breast cancer cell line
Maria Nattestad, Sara Goodwin, Karen Ng, Timour Baslan, Fritz J. Sedlazeck, Philipp Rescheneder, Tyler Garvin, Han Fang, James Gurtowski, Elizabeth Hutton, Elizabeth Tseng, Chen-Shan Chin, Timothy Beck, Yogi Sundaravadanam, Melissa Kramer, Eric Antoniou, John D. McPherson, James Hicks, William Richard McCombie, Michael C. Schatz
bioRxiv 174938; doi: https://doi.org/10.1101/174938

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