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- August 28, 2017.
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Author Information
- Claudia L Satizabal1,2,*,
- Hieab HH Adams3,4,*,
- Derrek P Hibar5,
- Charles C White6,7,
- Jason L Stein5,8,
- Markus Scholz9,10,
- Murali Sargurupremraj11,
- Neda Jahanshad5,
- Albert V Smith12,13,14,
- Joshua C Bis15,
- Xueqiu Jian16,
- Michelle Luciano17,
- Edith Hofer18,19,
- Alexander Teumer20,
- Sven J van der Lee3,
- Jingyun Yang21,22,
- Lisa R Yanek23,
- Tom V Lee24,
- Shuo Li25,
- Yanhui Hu26,
- Jia Yu Koh27,
- John D Eicher28,
- Sylvane Desrivières29,
- Alejandro Arias-Vasquez30,31,32,33,
- Ganesh Chauhan11,34,
- Lavinia Athanasiu35,36,
- Miguel E Renteria37,
- Sungeun Kim38,39,40,
- David Höhn41,
- Nicola J Armstrong42,
- Qiang Chen43,
- Avram J Holmes44,45,
- Anouk den Braber46,
- Iwona Kloszewska47,
- Micael Andersson48,49,
- Thomas Espeseth35,50,
- Oliver Grimm51,
- Lucija Abramovic52,
- Saud Alhusaini53,54,
- Yuri Milaneschi55,
- Martina Papmeyer56,57,
- Tomas Axelsson58,
- Stefan Ehrlich45,59,60,
- Roberto Roiz-Santiañez61,62,
- Bernd Kraemer63,
- Asta K Håberg64,65,
- Hannah J Jones66,67,68,
- G Bruce Pike69,
- Dan J Stein70,71,
- Allison Stevens60,
- Janita Bralten31,33,
- Meike W Vernooij3,4,
- Tamara B Harris72,
- Irina Filippi29,
- A Veronica Witte73,74,
- Tulio Guadalupe75,76,
- Katharina Wittfeld77,78,
- Thomas H Mosley79,
- James T Becker80,
- Nhat Trung Doan36,
- Saskia P Hagenaars17,
- Yasaman Saba81,
- Gabriel Cuellar-Partida82,
- Najaf Amin3,
- Saima Hilal83,84,
- Kwangsik Nho38,39,40,
- Nazanin Karbalai41,
- Konstantinos Arfanakis21,85,86,
- Diane M Becker23,
- David Ames87,88,
- Aaron L Goldman43,
- Phil H Lee45,89,90,91,92,
- Dorret I Boomsma46,
- Simon Lovestone93,94,
- Sudheer Giddaluru95,96,
- Stephanie Le Hellard95,96,
- Manuel Mattheisen97,98,99,100,101,
- Marc M Bohlken52,
- Dalia Kasperaviciute102,
- Lianne Schmaal55,103,104,
- Stephen M Lawrie56,
- Ingrid Agartz36,100,105,
- Esther Walton59,67,
- Diana Tordesillas-Gutierrez62,106,
- Gareth E Davies107,
- Jean Shin108,
- Jonathan C Ipser70,
- Louis N Vinke109,
- Martine Hoogman31,33,
- Maria J Knol3,
- Tianye Jia29,
- Ralph Burkhardt10,110,
- Marieke Klein31,33,
- Fabrice Crivello111,
- Deborah Janowitz77,
- Owen Carmichael112,
- Unn K Haukvik113,114,
- Benjamin S Aribisala115,116,
- Helena Schmidt81,
- Lachlan T Strike82,117,
- Ching-Yu Cheng27,118,
- Shannon L Risacher39,40,
- Benno Pütz41,
- Debra A Fleischman21,22,119,
- Amelia A Assareh120,
- Venkata S Mattay43,121,122,
- Randy L Buckner45,123,
- Patrizia Mecocci124,
- Anders M Dale125,126,
- Sven Cichon127,128,129,
- Marco P Boks52,
- Mar Matarin102,130,
- Brenda WJH Penninx55,
- Vince D Calhoun131,132,
- M Mallar Chakravarty133,134,
- Andre Marquand33,135,
- Christine Macare29,
- Shahrzad Kharabian Masouleh73,136,
- Jaap Oosterlaan137,138,139,
- Philippe Amouyel140,
- Katrin Hegenscheid141,
- Jerome I Rotter142,
- Andrew J Schork143,144,
- David CM Liewald17,
- Greig I De Zubicaray145,
- Tien Yin Wong27,118,
- Li Shen38,39,40,
- Philipp G Sämann41,
- Henry Brodaty120,146,
- Joshua L Roffman45,
- Eco JC De Geus46,
- Magda Tsolaki147,
- Susanne Erk148,
- Kristel R Van Eijk149,
- Gianpiero L Cavalleri150,
- Nic JA Van der Wee151,
- Andrew M McIntosh17,56,
- Randy L Gollub45,60,89,
- Kazima B Bulayeva152,
- Manon Bernard108,
- Jennifer S Richards30,33,153,
- Jayandra J Himali1,2,25,
- Markus Loeffler9,10,
- Nanda Rommelse32,33,154,
- Wolfgang Hoffmann78,155,
- Lars T Westlye35,156,
- Maria C Valdés Hernández115,157,
- Narelle K Hansell82,117,
- Theo GM Van Erp158,
- Christiane Wolf159,
- John BJ Kwok160,161,162,
- Bruno Vellas163,
- Andreas Heinz164,
- Loes M Olde Loohuis165,
- Norman Delanty54,166,
- Beng-Choon Ho167,
- Christopher RK Ching5,168,
- Elena Shumskaya31,33,135,169,
- Albert Hofman3,170,
- Dennis Van der Meer171,
- Georg Homuth172,
- Bruce M Psaty173,174,
- Mark Bastin115,157,
- Grant W Montgomery82,
- Tatiana M Foroud40,175,
- Simone Reppermund120,176,
- Jouke-Jan Hottenga46,
- Andrew Simmons177,178,179,
- Andreas Meyer-Lindenberg51,
- Wiepke Cahn52,
- Christopher D Whelan5,54,
- Marjolein MJ Van Donkelaar31,33,
- Qiong Yang25,
- Norbert Hosten141,
- Robert C Green89,180,
- Anbupalam Thalamuthu120,
- Sebastian Mohnke148,
- Hilleke E Hulshoff Pol52,
- Honghuang Lin2,181,
- Clifford R Jack Jr182,
- Peter R Schofield161,183,
- Thomas W Mühleisen129,184,
- Pauline Maillard169,
- Steven G Potkin158,
- Wei Wen120,
- Evan Fletcher169,
- Arthur W Toga185,
- Oliver Gruber63,
- Matthew Huentelman186,
- George Davey Smith67,
- Lenore J Launer72,
- Lars Nyberg48,49,187,
- Erik G Jönsson36,100,
- Benedicto Crespo-Facorro61,62,
- Nastassja Koen70,71,
- Douglas Greve60,188,
- André G Uitterlinden3,
- Daniel R Weinberger43,189,
- Vidar M Steen95,96,
- Iryna O Fedko190,
- Nynke A Groenewold70,
- Wiro J Niessen4,191,192,
- Roberto Toro193,
- Christophe Tzourio11,
- William T Longstreth Jr194,
- M Kamran Ikram3,118,
- Jordan W Smoller45,89,91,92,
- Marie-Jose Van Tol195,
- Jessika E Sussmann56,
- Tomas Paus196,
- Hervé Lemaître197,
- Bernard Mazoyer111,
- Ole A Andreassen35,36,
- Florian Holsboer41,198,199,
- Dick J Veltman55,
- Jessica A Turner132,200,
- Zdenka Pausova108,
- Gunter Schumann29,
- Daan Van Rooij30,33,201,
- Srdjan Djurovic95,202,
- Ian J Deary17,
- Katie L McMahon203,
- Bertram Müller-Myhsok41,204,205,
- Rachel M Brouwer52,
- Hilkka Soininen206,207,
- Massimo Pandolfo199,
- Thomas H Wassink167,
- Joshua W Cheung5,
- Thomas Wolfers31,33,
- Jean-Luc Martinot197,
- Marcel P Zwiers33,135,
- Matthias Nauck208,209,
- Ingrid Melle35,36,
- Nicholas G Martin82,
- Ryota Kanai210,211,212,
- Eric Westman213,
- René S Kahn52,
- Sanjay M Sisodiya102,
- Tonya White4,214,
- Arvin Saremi5,
- Hans van Bokhoven31,33,
- Han G Brunner31,33,215,216,
- Henry Völzke20,209,
- Margaret J Wright117,203,
- Dennis Van 't Ent46,
- Markus M Nöthen128,217,
- Roel A Ophoff52,165,
- Jan K Buitelaar30,33,154,
- Guillén Fernández30,33,
- Perminder S Sachdev120,218,
- Marcella Rietschel51,
- Neeltje EM Van Haren52,
- Simon E Fisher33,76,
- Alexa S Beiser2,25,
- Clyde Francks33,76,
- Andrew J Saykin39,40,175,
- Karen A Mather120,
- Nina Romanczuk-Seiferth164,
- Catharina A Hartman201,
- Anita L DeStefano2,25,
- Dirk J Heslenfeld219,
- Michael W Weiner220,221,
- Henrik Walter148,
- Pieter J Hoekstra201,
- Paul A Nyquist23,
- Barbara Franke31,32,33,
- David A Bennett21,22,
- Hans J Grabe77,78,
- Andrew D Johnson28,
- Christopher Chen83,84,
- Cornelia M van Duijn3,222,
- Oscar L Lopez223,
- Myriam Fornage224,
- Joanna A Wardlaw17,157,225,
- Reinhold Schmidt18,
- Charles DeCarli226,
- Philip L De Jager7,227,
- Arno Villringer73,74,
- Stéphanie Debette11,
- Vilmundur Gudnason13,14,
- Sarah E Medland82,
- Joshua M Shulman228,229,
- Paul M Thompson5,
- Sudha Seshadri1,2 and
- M Arfan Ikram3,4
- 1Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, 02118, USA
- 2The Framingham Heart Study, 73 Mt Wayte Ave, Framingham, Massachusetts, 01702, USA
- 3Department of Epidemiology, Erasmus MC, Rotterdam, 3015 CE, The Netherlands
- 4Department of Radiology and Nuclear Medicine, Erasmus MC, Rotterdam, 3015 CE, The Netherlands
- 5Imaging Genetics Center, USC Mark and Mary Stevens Neuroimaging & Informatics Institute, Keck School of Medicine of University of Southern California, Los Angeles, 90292, USA
- 6Program in Translational NeuroPsychiatric Genomics, Institute for the Neurosciences, Departments of Neurology and Psychiatry, Brigham and Women’s Hospital, Boston, Massachusetts, USA
- 7Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA
- 8Department of Genetics & UNC Neuroscience Center, University of North Carolina (UNC), Chapel Hill, North Carolina, 27599, USA
- 9Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, 04107 Leipzig, Germany
- 10LIFE - Leipzig Research Center for Civilization Diseases, University of Leipzig, Leipzig, Germany
- 11Inserm U1219, University of Bordeaux, Bordeaux University Hospital, Bordeaux, France
- 12Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, 48109, USA
- 13Faculty of Medicine, University of Iceland, 101
- 14Icelandic Heart Association, 201 Kopavogur, Iceland
- 15Cardiovascular Health Research Unit, Department of Medicine, University of Washington, 1730 Minor Avenue / Suite 1360 / Seattle, Washington 98101, USA
- 16The University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
- 17Centre for Cognitive Ageing and Cognitive Epidemiology, Psychology, University of Edinburgh, Edinburgh, EH8 9JZ, UK
- 18Clinical Division of Neurogeriatrics, Department of Neurology, Medical University of Graz, Austria
- 19Institute for Medical Informatics, Statistics and Documentation, Medical University of Graz, Austria
- 20Institute for Community Medicine, University Medicine Greifswald, Greifswald, 17489, Germany
- 21Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois, 60612, USA
- 22Department of Neurological Sciences, Rush University Medical Center, Chicago, Illinois, 60612, USA
- 23GeneSTAR Research Program, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
- 24Department of Neurology, Baylor College of Medicine, Houston, Texas 77030, USA
- 25Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, 02118, USA
- 26Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
- 27Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, 168751, Singapore
- 28National Heart, Lung and Blood Institute’s The Framingham Heart Study, Division of Intramural Research, Population Sciences Branch, Framingham, Massachusetts, 01702, USA
- 29MRC-SGDP Centre, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London, SE5 8AF, UK
- 30Department of Cognitive Neuroscience, Radboud University Medical Center, Nijmegen, The Netherlands. Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands
- 31Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands
- 32Department of Psychiatry, Radboud University Medical Center, Nijmegen, The Netherlands
- 33Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, The Netherlands
- 34Centre for Brain Research, Indian Institute of Science, Bangalore, India
- 35NORMENT - KG Jebsen Centre, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, 0315, Norway
- 36NORMENT - KG Jebsen Centre, Institute of Clinical Medicine, University of Oslo, Oslo, 0315, Norway
- 37Department of Genetics and Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia
- 38Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, 46202, USA
- 39Center for Neuroimaging, Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, 46202, USA
- 40Indiana Alzheimer Disease Center, Indiana University School of Medicine, Indianapolis, Indiana, 46202, USA
- 41Max Planck Institute of Psychiatry, Munich, 80804, Germany
- 42Mathematics and Statistics, Murdoch University, Perth, Western Australia, 6150, Australia
- 43Lieber Institute for Brain Development, Baltimore, 21205, USA
- 44Department of Psychology, Yale University, New Haven, 06520, USA
- 45Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
- 46Biological Psychology, Neuroscience Campus Amsterdam, Vrije Universiteit & Vrije Universiteit Medical Center, Amsterdam, 1081 BT, The Netherlands
- 47Medical University of Lodz, Lodz, 90-419, Poland
- 48Department of Integrative Medical Biology and Umeå center for Functional Brain Imaging, Umeå University, Umeå 901 87, Sweden
- 49Umeå Centre for Functional Brain Imaging (UFBI), Umeå University, Umeå 901 87, Sweden
- 50Department of Psychology, University of Oslo, Oslo, 0373, Norway
- 51Central Institute of Mental Health, Medical Faculty Mannheim, University Heidelberg, Mannheim, 68159, Germany
- 52Brain Center Rudolf Magnus, Department of Psychiatry, UMC Utrecht, Utrecht, 3584 CX, The Netherlands
- 53Department of Neurology and Neurosurgery, Montreal Neurological Institute, McGill University, Montreal, H3A 2B4, Canada
- 54The Royal College of Surgeons in Ireland, 123 St Stephen’s Green, Dublin 2, Ireland
- 55Department of Psychiatry, Amsterdam Neuroscience, VU University Medical Center, Amsterdam, 1007 MB, The Netherlands
- 56Division of Psychiatry, Royal Edinburgh Hospital, University of Edinburgh, Edinburgh, EH10 5HF, UK
- 57Division of Systems Neuroscience of Psychopathology, Translational Research Center, University Hospital of Psychiatry, University of Bern, Switzerland
- 58Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University, Box 1432, SE-751 44 Uppsala, Sweden
- 59Division of Psychological and Social Medicine and Developmental Neurosciences, Faculty of Medicine, TU Dresden, 01307 Germany
- 60Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, Massachusetts 02129, USA
- 61Department of Medicine and Psychiatry, University Hospital Marqués de Valdecilla, School of Medicine, University of Cantabria-IDIVAL, 39008 Santander, Spain
- 62CIBERSAM (Centro Investigación Biomédica en Red Salud Mental), Santander, 39011, Spain
- 63Section for Experimental Psychopathology and Neuroimaging, Dept of General Psychiatry, Heidelberg University, Heidelberg, 69120, Germany
- 64Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, 7491, Norway
- 65Department of Radiology, St. Olav’s Hospital, Trondheim University Hospital, Trondheim, 7030, Norway
- 66Centre for Academic Mental Health, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
- 67MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol, Oakfield House, Bristol BS8 2BN, UK
- 68NIHR Biomedical Research Centre at the University Hospitals Bristol NHS Foundation Trust and the University of Bristol, Bristol UK
- 69Departments of Radiology and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada T2N 4N1
- 70Department of Psychiatry and Mental Health, University of Cape Town, Observatory, Cape Town, 7925, South Africa
- 71South African Medical Research Council (SAMRC) Unit on Risk & Resilience in Mental Disorders, Cape Town, South Africa
- 72Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, National Institutes of Health, Bethesda, Maryland, 20892, USA
- 73Department of Neurology, Max Planck Institute of Cognitive and Brain Sciences, 04103 Leipzig, Germany
- 74Faculty of Medicine, CRC 1052 Obesity Mechanisms, University of Leipzig, Leipzig, Germany
- 75International Max Planck Research School for Language Sciences, Nijmegen, 6525 XD, The Netherlands
- 76Language and Genetics Department, Max Planck Institute for Psycholinguistics, Nijmegen, 6525 XD, The Netherlands
- 77Department of Psychiatry, University Medicine Greifswald, Greifswald, 17489, Germany
- 78German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, 17487, Germany
- 79Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, 39216, USA
- 80Departments of Psychiatry, Neurology, and Psychology, University of Pittsburgh, 3501 Forbes Ave, Suite 830, Pennsylvania 15213, USA
- 81Institute of Molecular Biology and Biochemistry, Centre for Molecular Medicine, Medical University of Graz, Austria
- 82QIMR Berghofer Medical Research Institute, Brisbane, 4006, Australia
- 83Department of Pharmacology, National University of Singapore, Singapore, 119077, Singapore
- 84Memory Aging and Cognition Center, National University Health System, Singapore
- 85Department of Biomedical Engineering, Illinois Institute of Technology, Chicago, IL 60616, USA
- 86Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, IL, USA
- 87Academic Unit for Psychiatry of Old Age, University of Melbourne, 3101, Australia
- 88National Ageing Research Institute, Royal Melbourne Hospital, Melbourne, 3052, Australia
- 89Harvard Medical School, Boston, Massachusetts, 02115, USA
- 90Lurie Center for Autism, Massachusetts General Hospital, Harvard Medical School, Lexington
- 91Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, 02114, USA
- 92Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Boston, Massachusetts, 02141, USA
- 93Department of Psychiatry, University of Oxford, Oxford, OX3 7JX, UK
- 94NIHR Dementia Biomedical Research Unit, King’s College London, London, SE5 8AF, UK
- 95NORMENT - KG Jebsen Centre for Psychosis Research, Department of Clinical Science, University of Bergen, 5021, Norway
- 96Dr Einar Martens Research Group for Biological Psychiatry, Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, 5021, Norway
- 97Center for integrated Sequencing, iSEQ, Aarhus University, Aarhus, DK-8000, Denmark
- 98Department of Biomedicine, Aarhus University, Aarhus, DK-8000, Denmark
- 99The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus and Copenhagen, DK-8000, Denmark
- 100Department of Clinical Neuroscience, Centre for Psychiatric Research, Karolinska Institutet, Stockholm, SE-171 77, Sweden
- 101Stockholm Health Care Services, Stockholm County Council, Stockholm, Sweden
- 102UCL Institute of Neurology, London, United Kingdom and Epilepsy Society, Bucks, UK
- 103Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC, Australia
- 104Orygen, The National Centre of Excellence in Youth Mental Health, Melbourne, Victoria, 3502, Australia
- 105Department of Research and Development, Diakonhjemmet Hospital, Oslo, 0319, Norway
- 106Neuroimaging Unit,Technological Facilities Valdecilla Biomedical Research Institute IDIVAL, Santander, Cantabria, Spain
- 107Avera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA
- 108Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada M5G 1X8
- 109Center for Systems Neuroscience, Boston University, Boston, Massachusetts, USA
- 110Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, 04109 Leipzig, Germany
- 111Groupe d’Imagerie Neurofonctionnelle, Institut des Maladies Neurodégénératives, UMR5293, CEA, CNRS, University of Bordeaux, Bordeaux University Hospital, Bordeaux, France
- 112Pennington Biomedical Research Center, Baton Rouge, LA, 70808
- 113Department of Adult Psychiatry, Institute for Clinical Medicine, University of Oslo, Norway
- 114NORMENT KG Jebsen Centre for Psychosis Research, Oslo University Hospital, Norway
- 115Brain Research Imaging Centre, University of Edinburgh, Edinburgh, EH4 2XU, UK
- 116Department of Computer Science, Lagos State University, Nigeria
- 117Queensland Brain Institute, University of Queensland, Brisbane, 4072, Australia
- 118Academic Medicine Research Institute, Duke-NUS Graduate Medical School, Singapore
- 119Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, 60612, USA
- 120Centre for Healthy Brain Ageing, School of Psychiatry, University of New South Wales, Sydney, 2052, Australia
- 121Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA
- 122Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA
- 123Department of Psychology, Center for Brain Science, Harvard University, Cambridge, Massachusetts, 02138, USA
- 124Section of Gerontology and Geriatrics, Department of Medicine, University of Perugia, Perugia, 06132, Italy
- 125Center for Multimodal Imaging and Genetics, University of California, San Diego, 92093, California, USA
- 126Departments of Neurosciences, Radiology, Psychiatry, and Cognitive Science, University of California, San Diego, 92093, California, USA
- 127Division of Medical Genetics, Department of Biomedicine, University of Basel, Basel, 4055, Switzerland
- 128Institute of Human Genetics, University of Bonn, Bonn, 53127, Germany
- 129Institute of Neuroscience and Medicine (INM-1), Research Centre Jülich, 52425 Jülich, Germany
- 130Reta Lila Weston Institute and Department of Molecular Neuroscience, UCL Institute of Neurology, London, WC1N 3BG, UK
- 131Department of ECE, University of New Mexico, Albuquerque, New Mexico, 87131, USA
- 132The Mind Research Network & LBERI, Albuquerque, New Mexico, 87106, USA
- 133Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, QC, Canada
- 134Departments of Psychiatry and Biological and Biomedical Engineering, McGill University, Montreal, QC, Canada
- 135Donders Centre for Cognitive Neuroimaging, Radboud University, Nijmegen, The Netherlands
- 136Institute of Neuroscience and Medicine, Brain & Behaviour (INM-7), Research Centre Jülich, Jülich, Germany
- 137Department of Clinical Neuropsychology, VU University Amsterdam, Amsterdam, 1081 HV, The Netherlands
- 138Department of Pediatrics, VU Medical Center, Amsterdam, The Netherlands
- 139Emma Children’s Hospital Amsterdam Medical Center, Amsterdam, The Netherlands
- 140Univ. Lille, Inserm, Centre Hosp. Univ Lille, Institut Pasteur de Lille, LabEx DISTALZUMR1167 - RID-AGE - Risk factors and molecular determinants of aging-related diseases, Epidemiology and Public Health Department, F-59000 Lille, France
- 141Institute of Diagnostic Radiology and Neuroradiology, University Medicine Greifswald, Greifswald, 17489, Germany
- 142Institute for Translational Genomics and Population Sciences, Los Angeles Biomedical Research Institute and Pediatrics at Harbor-UCLA Medical Center, Torrance, CA 90502
- 143Department of Cognitive Sciences, University of California, San Diego, 92161, USA
- 144Multimodal Imaging Laboratory, Department of Neurosciences, University of California, San Diego, 92093, USA
- 145Faculty of Health and Institute of Health and Biomedical Innovation, Queensland University of Technology (QUT), Brisbane, 4059, Australia
- 146Dementia Collaborative Research Centre - Assessment and Better Care, UNSW, Sydney, 2052, Australia
- 1473rd Department of Neurology, Aristotle University of Thessaloniki, Thessaloniki, ‘G. Papanicolaou Hospital, 57010, Greece
- 148Division of Mind and Brain Research, Department of Psychiatry and Psychotherapy CCM, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
- 149Brain Center Rudolf Magnus, Human Neurogenetics Unit, UMC Utrecht, Utrecht, 3584 CG, The Netherlands
- 150Department of Molecular and Cellular Therapeutics, the Royal College of Surgeons in Ireland, 123 St Stephen’s Green, Dublin 2, Ireland
- 151Department of Psychiatry and Leiden Institute for Brain and Cognition, Leiden University Medical Center, Leiden, 2333 ZA, The Netherlands
- 152Department of Evolution and Genetics, Dagestan State University, Makhachkala, 367000, Dagestan, Russia
- 153Department of Psychiatry, Interdisciplinary Center Psychopathology and Emotion regulation (ICPE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
- 154Karakter Child and Adolescent Psychiatry University Center, Nijmegen, The Netherlands
- 155Institute for Community Medicine, Section Epidemiology of Health Care and Community Health, University Medicine Greifswald, Greifswald, Germany
- 156NORMENT - KG Jebsen Centre, Department of Psychology, University of Oslo, Oslo, 0373, Norway
- 157Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, EH16 4SB, UK
- 158Department of Psychiatry and Human Behavior, University of California-Irvine, Irvine, California, 92617, USA
- 159University of Wuerzburg, Department of Psychiatry, Psychosomatics and Psychotherapy, Wuerzburg, Germany
- 160Brain and Mind Centre, University of Sydney, New South Wales, Australia
- 161Neuroscience Research Australia, Sydney, 2031, Australia
- 162University of New South Wales, Australia
- 163Department of Internal Medicine and Geriatric Medicine, INSERM U 558, University of Toulouse, Toulouse, France
- 164Department of Psychiatry and Psychotherapy, Charité Universitätsmedizin Berlin, CCM, Berlin, 10117, Germany
- 165Center for Neurobehavioral Genetics, University of California, Los Angeles, California, 90095, USA
- 166Neurology Division, Beaumont Hospital, Dublin, 9, Ireland
- 167Department of Psychiatry, Carver College of Medicine, University of Iowa, Iowa City, 52242, USA
- 168Interdepartmental Neuroscience Graduate Program, UCLA School of Medicine, Los Angeles, California 90095, USA
- 169Imaging of Dementia and Aging (IDeA) Laboratory, Department of Neurology, University of California-Davis, Davis, CA, 95618, USA
- 170Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, 02115, USA
- 171KG Jebsen Centre for Psychosis Research / Norwegian Centre for Mental Disorder Research (NORMENT), Institute of Clinical Medicine, University of Oslo, Oslo, Norway
- 172Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, 17489, Germany
- 173Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, Washington, 98101, USA
- 174Kaiser Permanent Washington Health Research Institute, Seattle, WA
- 175Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, 46202, USA
- 176Department of Developmental Disability Neuropsychiatry, School of Psychiatry, UNSW Medicine, Australia
- 177Biomedical Research Unit for Dementia, King’s College London, London, SE5 8AF, UK
- 178Department of Neuroimaging, Institute of Psychiatry, King’s College London, London, SE5 8AF, UK
- 179Division of Clinical Geriatrics, Department of Neurobiology, Care Sciences and Society, Karolinska Institute, Stockholm, Sweden
- 180Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts, 02115, USA
- 181Section of Computational Biomedicine, Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, 02118, USA
- 182Department of Radiology, Mayo Clinic, Rochester, Minnesota, 55905, USA
- 183School of Medical Sciences, UNSW, Sydney, 2052, Australia. Sciences, Umeå University, S-901 87 Umeå, Sweden
- 184Department of Biomedicine, University of Basel, Basel, Switzerland
- 185Laboratory of Neuro Imaging, USC Mark and Mary Stevens Neuroimaging and Informatics Institute, Keck School of Medicine of the University of Southern California, Los Angeles, California, 90033, USA
- 186Translational Genomics Research Institute, Neurogenomics Division, 445 N Fifth Street, Phoenix, Arizona 85004, USA
- 187Radiation Sciences, Umeå University, S-901 87 Umeå, Sweden
- 188Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
- 189Departments of Psychiatry, Neurology, Neuroscience and the Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, 21205, USA
- 190Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
- 191Imaging Physics, Faculty of Applied Sciences, Delft University of Technology, The Netherlands
- 192Department of Medical Informatics, Erasmus MC, Rotterdam, 3015 CE, The Netherlands
- 193Institut Pasteur, Paris, 75015, France
- 194Departments of Neurology and Epidemiology, University of Washington, Seattle, WA, USA, 325 Ninth Avenue, Seattle WA, 98104-2420, USA
- 195Neuroimaging Centre, University of Groningen, University Medical Center Groningen, Groningen, 9713 AW, The Netherlands
- 196Rotman Research Institute, University of Toronto, Toronto, Ontario, Canada M6A 2E1
- 197INSERM UMR 1000 “Neuroimaging and Psychiatry”, University Paris-Sud, University Paris-Saclay, University Paris Descartes; Service Hospitalier Frédéric Joliot, Orsay; and Maison de Solenn, Paris; France
- 198HMNC Brain Health, Munich, 80539, Germany
- 199Department of Neurology, Hopital Erasme, Universite Libre de Bruxelles, Brussels, 1070, Belgium
- 200Department of Psychology, Georgia State University, Atlanta, GA, USA
- 201Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
- 202Department of Medical Genetics, Oslo University Hospital, Oslo, 0450, Norway
- 203Centre for Advanced Imaging, University of Queensland, Brisbane, 4072, Australia
- 204Munich Cluster for Systems Neurology (SyNergy), Munich, 81377, Germany
- 205University of Liverpool, Institute of Translational Medicine, Liverpool, L69 3BX, UK
- 206Institute of Clinical Medicine, Neurology, University of Eastern Finland, Kuopio, FI-70211, Finland
- 207Neurocentre Neurology, Kuopio University Hospital, FI-70211, Finland
- 208Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, 17489, Germany
- 209German Center for Cardiovascular Research (DZHK eV), partner site Greifswald, Germany
- 210Department of Neuroinformatics, Araya, Inc., Tokyo, 105-0001, Japan
- 211Institute of Cognitive Neuroscience, University College London, London, WC1N 3AR, UK
- 212School of Psychology, University of Sussex, Brighton, BN1 9QH, UK
- 213Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, SE-141 83, Sweden
- 214Department of Child and Adolescent Psychiatry/Psychology, Erasmus MC-Sophia Children’s Hospital, Rotterdam, 3015 CE, The Netherlands
- 215Department of Clinical Genetics, Maastricht University Medical Center, Maastricht, 6200 MD, The Netherlands
- 216GROW School for Oncology and Developmental Biology, Maastricht, The Netherlands
- 217Department of Genomics, Life & Brain Center, University of Bonn, 53127, Germany
- 218Neuropsychiatric Institute, Prince of Wales Hospital, Sydney, 2031, Australia
- 219Department of Psychology, VU University Amsterdam, Amsterdam, 1081 BT, The Netherlands
- 220Center for Imaging of Neurodegenerative Disease, San Francisco VA Medical Center, University of California, San Francisco, 94121, USA
- 221Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, 94143, USA
- 222Leiden Academic Centre for Drug Research (LACDR), Leiden University, The Netherlands
- 223Departments of Neurology and Psychiatry, University of Pittsburgh, 3501 Forbes Ave, Suite 830 Pittsburgh PA 15213, USA
- 224Institute of Molecular Medicine and Human Genetics Center, University of Texas Health Science Center at Houston, Houston, Texas, 77030, USA
- 225UK Dementia Research Institute at the University of Edinburgh, Chancellor’s Building, Little France, Edinburgh H16 4SB
- 226Department of Neurology and Center for Neuroscience, University of California at Davis, Sacramento, California, 95817, USA
- 227Center for Translational & Computational Neuroimmunology, Department of Neurology, Columbia University Medical Center, New York, NY 10032, USA
- 228Departments of Neurology, Molecular & Human Genetics, Neuroscience, and Program in Developmental Biology, Baylor College of Medicine, Houston, Texas, 77030, USA
- 229Jan and Dan Duncan Neurological Research Institute, Texas Children’s Hospital, Houston, TX, USA
- ↵*Correspondence to: Dr. Claudia L. Satizabal
Boston University School of Medicine and The Framingham Heart Study, 72 East Concord Street, B-601, Boston, MA 02118-2526, USA. Phone: +1 617-638-5398; Email: clausati{at}bu.edu or, Dr. M. Arfan Ikram Erasmus
, University Medical Center Rotterdam, P.O. Box 2040, 3000 CA, Rotterdam, The Netherlands. Phone: +31 10 7043930; E-mail: m.a.ikram{at}erasmusmc.nl