New Results
Community assessment of cancer drug combination screens identifies strategies for synergy prediction
Michael P Menden, Dennis Wang, Yuanfang Guan, Michael Mason, Bence Szalai, Krishna C Bulusu, Thomas Yu, Jaewoo Kang, Minji Jeon, Russ Wolfinger, Tin Nguyen, Mikhail Zaslavskiy, Jang SockAstraZeneca-Sanger Drug Combination DREAM Consortium, In, Jang SockAstraZeneca-Sanger Drug Combination DREAM Consortium, In, Zara Ghazoui, Mehmet Eren Ahsen, Robert Vogel, Elias Chaibub Neto, Thea Norman, Eric KY Tang, Mathew J Garnett, Giovanni Di Veroli, Christian Michel Zwaan, Stephen Fawell, Gustavo Stolovitzky, Justin Guinney, Jonathan R. Dry, Julio Saez-Rodriguez
doi: https://doi.org/10.1101/200451
Michael P Menden
1Oncology Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK
2European Bioinformatics Institute, European Molecular Biology Laboratory, Cambridge, UK
Dennis Wang
1Oncology Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK
3Sheffield Institute for Translational Neuroscience, Sheffield, UK
4NIHR Sheffield Biomedical Research Centre, Sheffield, UK
Yuanfang Guan
5Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, USA
Michael Mason
6Sage Bionetworks, Seattle WA, USA
Bence Szalai
7Department of Physiology, Faculty of Medicine, Semmelweis University, Budapest, Hungary
8Laboratory of Molecular Physiology, Hungarian Academy of Sciences and Semmelweis University (MTA-SE), Budapest, Hungary
9RWTH Aachen University, Faculty of Medicine, Joint Research Center for Computational Biomedicine, Aachen, Germany
Krishna C Bulusu
1Oncology Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK
Thomas Yu
6Sage Bionetworks, Seattle WA, USA
Jaewoo Kang
10Department of Computer Science and Engineering, Korea University, Seoul, Korea
11Interdisciplinary Graduate Program in Bioinformatics, Korea University, Seoul, Korea
Minji Jeon
10Department of Computer Science and Engineering, Korea University, Seoul, Korea
Russ Wolfinger
12SAS Institute, Inc., Cary, NC, USA
Tin Nguyen
13Department of Computer Science and Engineering, University of Nevada, Reno, USA
Mikhail Zaslavskiy
14Independent consultant in computational biology, Paris, France
Jang Sock
6Sage Bionetworks, Seattle WA, USA
Jang Sock
6Sage Bionetworks, Seattle WA, USA
Zara Ghazoui
1Oncology Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK
Mehmet Eren Ahsen
15IBM Thomas J. Watson Research Center, Yorktown Heights, New York, USA
Robert Vogel
15IBM Thomas J. Watson Research Center, Yorktown Heights, New York, USA
Elias Chaibub Neto
6Sage Bionetworks, Seattle WA, USA
Thea Norman
6Sage Bionetworks, Seattle WA, USA
Eric KY Tang
1Oncology Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK
Mathew J Garnett
16Wellcome Trust Sanger Institute, Hinxton, UK
Giovanni Di Veroli
1Oncology Innovative Medicines and Early Development, AstraZeneca, Cambridge, UK
Christian Michel Zwaan
11Interdisciplinary Graduate Program in Bioinformatics, Korea University, Seoul, Korea
Stephen Fawell
17Oncology Innovative Medicines and Early Development, AstraZeneca R&D Boston, Waltham, MA, USA
Gustavo Stolovitzky
15IBM Thomas J. Watson Research Center, Yorktown Heights, New York, USA
18Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, USA
Justin Guinney
6Sage Bionetworks, Seattle WA, USA
Jonathan R. Dry
13Department of Computer Science and Engineering, University of Nevada, Reno, USA
Julio Saez-Rodriguez
2European Bioinformatics Institute, European Molecular Biology Laboratory, Cambridge, UK
9RWTH Aachen University, Faculty of Medicine, Joint Research Center for Computational Biomedicine, Aachen, Germany
Article usage
Posted October 09, 2017.
Community assessment of cancer drug combination screens identifies strategies for synergy prediction
Michael P Menden, Dennis Wang, Yuanfang Guan, Michael Mason, Bence Szalai, Krishna C Bulusu, Thomas Yu, Jaewoo Kang, Minji Jeon, Russ Wolfinger, Tin Nguyen, Mikhail Zaslavskiy, Jang SockAstraZeneca-Sanger Drug Combination DREAM Consortium, In, Jang SockAstraZeneca-Sanger Drug Combination DREAM Consortium, In, Zara Ghazoui, Mehmet Eren Ahsen, Robert Vogel, Elias Chaibub Neto, Thea Norman, Eric KY Tang, Mathew J Garnett, Giovanni Di Veroli, Christian Michel Zwaan, Stephen Fawell, Gustavo Stolovitzky, Justin Guinney, Jonathan R. Dry, Julio Saez-Rodriguez
bioRxiv 200451; doi: https://doi.org/10.1101/200451
Community assessment of cancer drug combination screens identifies strategies for synergy prediction
Michael P Menden, Dennis Wang, Yuanfang Guan, Michael Mason, Bence Szalai, Krishna C Bulusu, Thomas Yu, Jaewoo Kang, Minji Jeon, Russ Wolfinger, Tin Nguyen, Mikhail Zaslavskiy, Jang SockAstraZeneca-Sanger Drug Combination DREAM Consortium, In, Jang SockAstraZeneca-Sanger Drug Combination DREAM Consortium, In, Zara Ghazoui, Mehmet Eren Ahsen, Robert Vogel, Elias Chaibub Neto, Thea Norman, Eric KY Tang, Mathew J Garnett, Giovanni Di Veroli, Christian Michel Zwaan, Stephen Fawell, Gustavo Stolovitzky, Justin Guinney, Jonathan R. Dry, Julio Saez-Rodriguez
bioRxiv 200451; doi: https://doi.org/10.1101/200451
Subject Area
Subject Areas
- Biochemistry (11730)
- Bioengineering (8743)
- Bioinformatics (29179)
- Biophysics (14964)
- Cancer Biology (12080)
- Cell Biology (17399)
- Clinical Trials (138)
- Developmental Biology (9417)
- Ecology (14174)
- Epidemiology (2067)
- Evolutionary Biology (18294)
- Genetics (12233)
- Genomics (16791)
- Immunology (11858)
- Microbiology (28051)
- Molecular Biology (11575)
- Neuroscience (60919)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4955)
- Plant Biology (10422)
- Synthetic Biology (2881)
- Systems Biology (7338)
- Zoology (1650)