Article Information
- November 8, 2017.
Author Information
- Rozaimi Razali1*,
- Salim Bougouffa1*,
- Mitchell J. L. Morton2*,
- Damien J. Lightfoot2,3*,
- Intikhab Alam1,4,
- Magbubah Essack1,
- Stefan T. Arold1,2,
- Allan Kamau1,4,
- Sandra M. Schmöckel2,
- Yveline Pailles2,
- Mohammed Shahid5,
- Craig T. Michell6,7,
- Salim Al-Babili2,
- Yung Shwen Ho2,
- Mark Tester2,
- Vladimir B. Bajic1,4,# and
- Sónia Negrão2,#
- 1King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Thuwal 23955-6900, Kingdom of Saudi Arabia
- 2King Abdullah University of Science and Technology (KAUST), Division of Biological and Environmental Sciences and Engineering, Thuwal, 23955-6900, Kingdom of Saudi Arabia
- 3King Abdullah University of Science and Technology (KAUST), Division of Biological and Environmental Sciences & Engineering, KAUST Environmental Epigenetic Program (KEEP), Thuwal 23955-6900, Kingdom of Saudi Arabia (present address).
- 4King Abdullah University of Science and Technology (KAUST), Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), Thuwal 23955-6900, Kingdom of Saudi Arabia
- 5International Center for Biosaline Agriculture (ICBA), PO Box 14660, Dubai, United Arab Emirates.
- 6King Abdullah University of Science and Technology (KAUST), Red Sea Research Center (RSRC), Biological and Environmental Sciences & Engineering Division (BESE), Thuwal, 23955-6900, Kingdom of Saudi Arabia
- 7Department of Environmental and Biological Sciences, University of Eastern Finland, Yliopistokatu 7, FI-80101, Joensuu, Finland (present address)
- ↵#Corresponding authors:
V.B. Bajic; King Abdullah University of Science and Technology (KAUST), Computational Bioscience Research Center (CBRC), Thuwal 23955-6900, Kingdom of Saudi Arabia; +966 12 8082386; vladimir.bajic{at}kaust.edu.sa S. Negrão; King Abdullah University of Science and Technology (KAUST), Division of Biological and Environmental Sciences and Engineering, Thuwal, 23955-6900, Kingdom of Saudi Arabia; &966 8082569; snegrao{at}kaust.edu.sa
Author contribution RR, SB, MJLM and DJL conceived and designed the analyses and managed particular components of the project. RR and SB performed the bioinformatics analyses, which included the compilation of genome scaffolds, annotation and genomic analyses. MJLM produced and analyzed the field data, performed the KO enrichment analysis and oversaw its biological context for data interpretation. RR performed the phylogenetic analyses. DJL produced the OrthoMCL results. SB and DJL performed the candidate gene analyses. IA and AK developed the computational tool Dragon Eukaryotic Analyses Platform (DEAP). ME and SA-B analyzed the inositol pathway and provided its biological context. STA performed the computational structure–function analysis of the I3PS protein. YP performed the myo-inositol quantification and analyzed the Na and K concentration, and SA-B provided its metabolic context. MS performed the field trial supervision and phenotypic data collection. MJLM, CTM and SMS prepared materials and undertook sequencing activities. DJL and YSH contributed to the bioinformatics and genomic analyses. RR, SB, MJLM, DJL and SN organized the manuscript, analyzed the data, and wrote the article. SN, MT and VBB designed the research, supervised the project and reviewed the article. All authors contributed to the writing of the paper. RR, SB, MJLM and DJL contributed equally.