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- November 14, 2017.
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- Version 1 (June 9, 2017 - 12:40).
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license.
Author Information
- Andrea Ganna1,2,3,4,*,
- Kyle F. Satterstrom1,2,3,
- Seyedeh M Zekavat2,5,
- Indraniel Das6,7,
- Mitja I. Kurki1,2,8,
- Claire Churchhouse1,2,3,
- Jessica Alfoldi1,2,
- Alicia R. Martin1,2,3,
- Aki S. Havulinna8,21,
- Andrea Byrnes1,2,3,
- Wesley K. Thompson9,10,11,12,
- Philip R. Nielsen11,13,14,
- Konrad J. Karczewski1,2,
- Elmo Saarentaus8,
- Manuel A. Rivas15,
- Namrata Gupta2,
- Olli Pietiläinen3,16,
- Connor A Emdin2,
- Francesco Lescai11,17,18,
- Jonas Bybjerg-Grauholm11,19,
- Jason Flannick2,5,
- on behalf of GoT2D/T2D-GENES consortium,
- Josep Mercader2,5,
- Miriam Udler,
- on behalf of SIGMA consortium, Helmsley IBD Exome Sequencing Project, FinMetSeq Consortium, iPSYCH-Broad Consortium2,5,
- Markku Laakso20,
- Veikko Salomaa21,
- Christina Hultman4,
- Samuli Ripatti8,22,23,
- Eija Hämäläinen8,
- Jukka S Moilanen24,
- Jarmo Körkkö24,
- Outi Kuismin24,
- Merete Nordentoft11,25,
- David M. Hougaard11,19,
- Ole Mors11,26,
- Thomas Werge11,10,27,
- Preben Bo Mortensen11,13,14,17,
- Daniel MacArthur1,2,
- Mark J. Daly1,2,3,
- Patrick F. Sullivan4,28,
- Adam E. Locke6,7,
- Aarno Palotie1,2,3,8,
- Anders D. Børglum11,17,18,
- Sekar Kathiresan2,5 and
- Benjamin M. Neale1,2,3,*
- 1Analytic and Translational Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
- 2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
- 3Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
- 4Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
- 5Center for Genomic Medicine, Massachusetts General Hospital and Department of Medicine, Harvard Medical School, Boston, MA, USA.
- 6McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA.
- 7Department of Biostatistics and Center for Statistical Genetics, University of Michigan School of Public Health, Ann Arbor, MI, USA.
- 8Institute for Molecular Medicine Finland, FIMM, University of Helsinki, Helsinki, Finland.
- 9Department of Psychiatry, University of California, San Diego, USA.
- 10Institute of Biological Psychiatry, MHC Sct. Hans, Mental Health Services Copenhagen, Roskilde, Denmark.
- 11The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.
- 12KG Jebsen Centre for Psychosis Research, Norway Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.
- 13National Centre for Register-based Research, School of Business and Social Sciences, Aarhus University, Aarhus, Denmark.
- 14Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark.
- 15Department of Biomedical Data Science, Stanford University, Stanford, CA, USA.
- 16Department of Stem Cell and Regenerative Biology, University of Harvard, Cambridge, MA, USA.
- 17iSEQ, Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark
- 18Department of Biomedicine - Human Genetics, Aarhus University, Aarhus, Denmark.
- 19Center for Neonatal Screening, Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark
- 20Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, Kuopio, Finland
- 21Department of Health, THL-National Institute for Health and Welfare, Helsinki, Finland.
- 22Department of Public Health, University of Helsinki, Helsinki, Finland.
- 23Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.
- 24Department of Clinical Genetics, Oulu University Hospital, Medical Research Center Oulu and PEDEGO Research Unit, University of Oulu, Oulu, Finland
- 25Mental Health Services in the Capital Region of Denmark, Mental Health Center Copenhagen, University of Copenhagen, Copenhagen, Denmark.
- 26Psychosis Research Unit, Aarhus University Hospital, Risskov, Denmark.
- 27Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark
- 28Departments of Genetics and Psychiatry, University of North Carolina, Chapel Hill, NC, USA.
- ↵*Correspondence to: Andrea Ganna <aganna{at}broadinstitute.org>; Benjamin Neale <bneale{at}broadinstitute.org>