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Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development
View ORCID ProfileLaura M. Huckins, View ORCID ProfileAmanda Dobbyn, View ORCID ProfileDouglas M. Ruderfer, View ORCID ProfileGabriel Hoffman, View ORCID ProfileWeiqing Wang, View ORCID ProfileAntonio Pardinas, Veera M Rajagopal, View ORCID ProfileThomas D. Als, Hoang Nguyen, Kiran Girdhar, James Boocock, Panos Roussos, Menachem Fromer, View ORCID ProfileRobin Kramer, View ORCID ProfileEnrico Domencini, View ORCID ProfileEric Gamazon, View ORCID ProfileShaun Purcell, CommonMind Consortium, the Schizophrenia Working Group of the Psychiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group, Ditte Demontis, Anders D. Børglum, James Walters, Michael O’Donovan, View ORCID ProfilePatrick Sullivan, Michael Owen, View ORCID ProfileBernie Devlin, View ORCID ProfileSolveig K. Sieberts, View ORCID ProfileNancy Cox, View ORCID ProfileHae Kyung Im, View ORCID ProfilePamela Sklar, View ORCID ProfileEli A. Stahl
doi: https://doi.org/10.1101/222596
Laura M. Huckins
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
Amanda Dobbyn
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
Douglas M. Ruderfer
3Vanderbilt University Medical Center, Nashville, TN;
Gabriel Hoffman
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
4Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, NYC, NY, USA;
Weiqing Wang
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
Antonio Pardinas
5MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK;
Veera M Rajagopal
6Department of Biomedicine, Aarhus University, Aarhus, Denmark
15The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.
16Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark.
Thomas D. Als
6Department of Biomedicine, Aarhus University, Aarhus, Denmark
15The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.
16Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark.
Hoang Nguyen
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
Kiran Girdhar
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
James Boocock
7Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA;
Panos Roussos
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
Menachem Fromer
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
Robin Kramer
8Human Brain Collection Core, National Institute of Mental Health, Bethesda, MD, USA;
Enrico Domencini
9Laboratory of Neurogenomic Biomarkers, Centre for Integrative Biology (CIBIO), University of Trento, Trento, Italy;
Eric Gamazon
3Vanderbilt University Medical Center, Nashville, TN;
14Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA
Shaun Purcell
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
4Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, NYC, NY, USA;
6Department of Biomedicine, Aarhus University, Aarhus, Denmark
15The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.
16Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark.
Anders D. Børglum
6Department of Biomedicine, Aarhus University, Aarhus, Denmark
15The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Denmark.
16Center for Integrative Sequencing, Aarhus University, Aarhus, Denmark.
James Walters
5MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK;
Michael O’Donovan
5MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK;
Patrick Sullivan
10University of North Carolina at Chapel Hill, NC, USA
11Karolinska Institutet, Stockholm, Sweden
Michael Owen
5MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, UK;
Bernie Devlin
12Department of Psychiatry, University of Pittsburgh, Pittsburgh, PA, USA;
Solveig K. Sieberts
13Systems Biology, Sage Bionetworks, Seattle, WA, USA;
Nancy Cox
3Vanderbilt University Medical Center, Nashville, TN;
14Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA
Hae Kyung Im
14Section of Genetic Medicine, Department of Medicine, University of Chicago, Chicago, Illinois, USA
Pamela Sklar
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
4Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, NYC, NY, USA;
Eli A. Stahl
1Division of Psychiatric Genomic, Icahn School of Medicine at Mount Sinai, NYC, NY;
2Department of Genetics and Genomics, Icahn School of Medicine at Mount Sinai, NYC, NY;
Article usage
Posted November 21, 2017.
Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development
Laura M. Huckins, Amanda Dobbyn, Douglas M. Ruderfer, Gabriel Hoffman, Weiqing Wang, Antonio Pardinas, Veera M Rajagopal, Thomas D. Als, Hoang Nguyen, Kiran Girdhar, James Boocock, Panos Roussos, Menachem Fromer, Robin Kramer, Enrico Domencini, Eric Gamazon, Shaun Purcell, CommonMind Consortium, the Schizophrenia Working Group of the Psychiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group, Ditte Demontis, Anders D. Børglum, James Walters, Michael O’Donovan, Patrick Sullivan, Michael Owen, Bernie Devlin, Solveig K. Sieberts, Nancy Cox, Hae Kyung Im, Pamela Sklar, Eli A. Stahl
bioRxiv 222596; doi: https://doi.org/10.1101/222596
Gene expression imputation across multiple brain regions reveals schizophrenia risk throughout development
Laura M. Huckins, Amanda Dobbyn, Douglas M. Ruderfer, Gabriel Hoffman, Weiqing Wang, Antonio Pardinas, Veera M Rajagopal, Thomas D. Als, Hoang Nguyen, Kiran Girdhar, James Boocock, Panos Roussos, Menachem Fromer, Robin Kramer, Enrico Domencini, Eric Gamazon, Shaun Purcell, CommonMind Consortium, the Schizophrenia Working Group of the Psychiatric Genomics Consortium, iPSYCH-GEMS Schizophrenia Working Group, Ditte Demontis, Anders D. Børglum, James Walters, Michael O’Donovan, Patrick Sullivan, Michael Owen, Bernie Devlin, Solveig K. Sieberts, Nancy Cox, Hae Kyung Im, Pamela Sklar, Eli A. Stahl
bioRxiv 222596; doi: https://doi.org/10.1101/222596
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