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Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity
Nitin Roper, Shaojian Gao, Tapan K. Maity, A. Rouf Banday, Xu Zhang, Abhilash Venugopalan, Constance M. Cultraro, Rajesh Patidar, Sivasish Sindiri, Alexandr Goncearenco, Anna R. Panchenko, Romi Biswas, Anish Thomas, Arun Rajan, Corey A. Carter, David Kleiner, Stephen Hewitt, Javed Khan, Ludmila Prokunina-Olsson, Udayan Guha
doi: https://doi.org/10.1101/301390
Nitin Roper
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Shaojian Gao
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Tapan K. Maity
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
A. Rouf Banday
2Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, MD;.
Xu Zhang
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Abhilash Venugopalan
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Constance M. Cultraro
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Rajesh Patidar
3Genetics Branch, CCR, NCI, NIH, Bethesda, MD;
Sivasish Sindiri
3Genetics Branch, CCR, NCI, NIH, Bethesda, MD;
Alexandr Goncearenco
4National Center for Biotechnology Information, NIH, Bethesda, MD;
Anna R. Panchenko
4National Center for Biotechnology Information, NIH, Bethesda, MD;
Romi Biswas
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Anish Thomas
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Arun Rajan
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Corey A. Carter
5Walter Reed National Military Medical Center, Bethesda, MD;
David Kleiner
6Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD.
Stephen Hewitt
6Laboratory of Pathology, CCR, NCI, NIH, Bethesda, MD.
Javed Khan
3Genetics Branch, CCR, NCI, NIH, Bethesda, MD;
Ludmila Prokunina-Olsson
2Laboratory of Translational Genomics, Division of Cancer Epidemiology and Genetics, NCI, NIH, Bethesda, MD;.
Udayan Guha
1Thoracic and Gastrointestinal Oncology Branch, Center for Cancer Research, NCI, NIH, Bethesda, MD;
Article usage
Posted April 14, 2018.
Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity
Nitin Roper, Shaojian Gao, Tapan K. Maity, A. Rouf Banday, Xu Zhang, Abhilash Venugopalan, Constance M. Cultraro, Rajesh Patidar, Sivasish Sindiri, Alexandr Goncearenco, Anna R. Panchenko, Romi Biswas, Anish Thomas, Arun Rajan, Corey A. Carter, David Kleiner, Stephen Hewitt, Javed Khan, Ludmila Prokunina-Olsson, Udayan Guha
bioRxiv 301390; doi: https://doi.org/10.1101/301390
Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity
Nitin Roper, Shaojian Gao, Tapan K. Maity, A. Rouf Banday, Xu Zhang, Abhilash Venugopalan, Constance M. Cultraro, Rajesh Patidar, Sivasish Sindiri, Alexandr Goncearenco, Anna R. Panchenko, Romi Biswas, Anish Thomas, Arun Rajan, Corey A. Carter, David Kleiner, Stephen Hewitt, Javed Khan, Ludmila Prokunina-Olsson, Udayan Guha
bioRxiv 301390; doi: https://doi.org/10.1101/301390
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