Abstract
Small-angle X-ray scattering (SAXS) is a highly popular technique to assess the native three-dimensional structure of biological macromolecules in solution. Here we introduce a statistical criterion, Z-score, as a novel quality measure of SAXS-based structural models which positively correlates with data quality. We propose that, besides a goodness-of-fit (GOF) measure such as reduced χ2, the Z-score reflecting the ability of a given SAXS curve to differentiate between possible models should always be reported.
Copyright
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