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Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications
Carl C. Ward, Jordan I. Kleinman, Clive Yik Sham Chung, Kenneth Kim, Yana Petri, Patrick S. Lee, Jason R. Thomas, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Daniel K. Nomura
doi: https://doi.org/10.1101/439125
Carl C. Ward
1Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
Jordan I. Kleinman
1Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
Clive Yik Sham Chung
1Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
Kenneth Kim
3Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
6Vertex Pharmaceuticals, Boston, MA 02210
Yana Petri
1Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
Patrick S. Lee
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
4Novartis Institutes for BioMedical Research, Emeryville, CA 94608
Jason R. Thomas
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
5Novartis Institutes for BioMedical Research, Cambridge, MA 02139
6Vertex Pharmaceuticals, Boston, MA 02210
John A. Tallarico
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
5Novartis Institutes for BioMedical Research, Cambridge, MA 02139
Jeffrey M. McKenna
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
5Novartis Institutes for BioMedical Research, Cambridge, MA 02139
Markus Schirle
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
5Novartis Institutes for BioMedical Research, Cambridge, MA 02139
Daniel K. Nomura
1Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720
2Novartis-Berkeley Center for Proteomics and Chemistry Technologies
3Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720
7Department of Nutritional Sciences and Toxicology, University of California, Berkeley, Berkeley, CA 94720
Article usage
Posted October 16, 2018.
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications
Carl C. Ward, Jordan I. Kleinman, Clive Yik Sham Chung, Kenneth Kim, Yana Petri, Patrick S. Lee, Jason R. Thomas, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Daniel K. Nomura
bioRxiv 439125; doi: https://doi.org/10.1101/439125
Covalent Ligand Screening Uncovers a RNF4 E3 Ligase Recruiter for Targeted Protein Degradation Applications
Carl C. Ward, Jordan I. Kleinman, Clive Yik Sham Chung, Kenneth Kim, Yana Petri, Patrick S. Lee, Jason R. Thomas, John A. Tallarico, Jeffrey M. McKenna, Markus Schirle, Daniel K. Nomura
bioRxiv 439125; doi: https://doi.org/10.1101/439125
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