New Results
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
View ORCID ProfileDavid H. Brann, View ORCID ProfileTatsuya Tsukahara, View ORCID ProfileCaleb Weinreb, Marcela Lipovsek, View ORCID ProfileKoen Van den Berge, Boying Gong, Rebecca Chance, Iain C. Macaulay, Hsin-jung Chou, Russell Fletcher, View ORCID ProfileDiya Das, View ORCID ProfileKelly Street, View ORCID ProfileHector Roux de Bezieux, Yoon-Gi Choi, Davide Risso, Sandrine Dudoit, View ORCID ProfileElizabeth Purdom, Jonathan S. Mill, Ralph Abi Hachem, Hiroaki Matsunami, Darren W. Logan, Bradley J. Goldstein, Matthew S. Grubb, John Ngai, View ORCID ProfileSandeep Robert Datta
doi: https://doi.org/10.1101/2020.03.25.009084
David H. Brann
1Harvard Medical School Department of Neurobiology, Boston MA 02115 USA
Tatsuya Tsukahara
1Harvard Medical School Department of Neurobiology, Boston MA 02115 USA
Caleb Weinreb
1Harvard Medical School Department of Neurobiology, Boston MA 02115 USA
Marcela Lipovsek
2Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King’s College London, London SE1 1UL, UK
Koen Van den Berge
3Department of Statistics, University of California, Berkeley, CA 94720
4Department of Applied Mathematics, Computer Science and Statistics, Ghent University, Ghent, Belgium
Boying Gong
5Division of Biostatistics, School of Public Health, University of California, Berkeley, CA 94720
Rebecca Chance
6Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720
Iain C. Macaulay
7Earlham Institute, Norwich Research Park, Norwich, NR4 7UZ, UK
Hsin-jung Chou
6Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720
Russell Fletcher
6Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720
8Surrozen, Inc., South San Francisco, CA 94080
Diya Das
6Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720
9Genentech, Inc., South San Francisco, CA 94080
10Berkeley Institute for Data Science, University of California, Berkeley
Kelly Street
11Department of Data Sciences, Dana-Farber Cancer Institute, Boston, MA
12Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA
Hector Roux de Bezieux
5Division of Biostatistics, School of Public Health, University of California, Berkeley, CA 94720
13Center for Computational Biology, University of California, Berkeley, CA 94720
Yoon-Gi Choi
14QB3 Functional Genomics Laboratory, University of California, Berkeley, CA 94720
Davide Risso
15Department of Statistical Sciences, University of Padova, Padova, Italy
Sandrine Dudoit
3Department of Statistics, University of California, Berkeley, CA 94720
5Division of Biostatistics, School of Public Health, University of California, Berkeley, CA 94720
Elizabeth Purdom
5Division of Biostatistics, School of Public Health, University of California, Berkeley, CA 94720
Jonathan S. Mill
16University of Exeter Medical School, College of Medicine & Health, University of Exeter, Exeter EX2 5DW, UK16
Ralph Abi Hachem
17Duke University School of Medicine Department of Head and Neck Surgery & Communication Sciences, Durham, NC 27717 USA
Hiroaki Matsunami
18Duke University School of Medicine Department of Molecular Genetics and Microbiology, Department of Neurobiology, Duke Institute for Brain Sciences, Durham, NC 27717 US
Darren W. Logan
19Waltham Petcare Science Institute, Leicestershire LE14 4RT, UK
Bradley J. Goldstein
17Duke University School of Medicine Department of Head and Neck Surgery & Communication Sciences, Durham, NC 27717 USA
Matthew S. Grubb
2Centre for Developmental Neurobiology, Institute of Psychiatry, Psychology and Neuroscience (IoPPN), King’s College London, London SE1 1UL, UK
John Ngai
6Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720
14QB3 Functional Genomics Laboratory, University of California, Berkeley, CA 94720
20Helen Wills Neuroscience Institute, University of California, Berkeley, CA 94720
Sandeep Robert Datta
1Harvard Medical School Department of Neurobiology, Boston MA 02115 USA
Posted May 18, 2020.
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
David H. Brann, Tatsuya Tsukahara, Caleb Weinreb, Marcela Lipovsek, Koen Van den Berge, Boying Gong, Rebecca Chance, Iain C. Macaulay, Hsin-jung Chou, Russell Fletcher, Diya Das, Kelly Street, Hector Roux de Bezieux, Yoon-Gi Choi, Davide Risso, Sandrine Dudoit, Elizabeth Purdom, Jonathan S. Mill, Ralph Abi Hachem, Hiroaki Matsunami, Darren W. Logan, Bradley J. Goldstein, Matthew S. Grubb, John Ngai, Sandeep Robert Datta
bioRxiv 2020.03.25.009084; doi: https://doi.org/10.1101/2020.03.25.009084
Non-neuronal expression of SARS-CoV-2 entry genes in the olfactory system suggests mechanisms underlying COVID-19-associated anosmia
David H. Brann, Tatsuya Tsukahara, Caleb Weinreb, Marcela Lipovsek, Koen Van den Berge, Boying Gong, Rebecca Chance, Iain C. Macaulay, Hsin-jung Chou, Russell Fletcher, Diya Das, Kelly Street, Hector Roux de Bezieux, Yoon-Gi Choi, Davide Risso, Sandrine Dudoit, Elizabeth Purdom, Jonathan S. Mill, Ralph Abi Hachem, Hiroaki Matsunami, Darren W. Logan, Bradley J. Goldstein, Matthew S. Grubb, John Ngai, Sandeep Robert Datta
bioRxiv 2020.03.25.009084; doi: https://doi.org/10.1101/2020.03.25.009084
Subject Area
Subject Areas
- Biochemistry (11753)
- Bioengineering (8754)
- Bioinformatics (29205)
- Biophysics (14975)
- Cancer Biology (12102)
- Cell Biology (17414)
- Clinical Trials (138)
- Developmental Biology (9423)
- Ecology (14185)
- Epidemiology (2067)
- Evolutionary Biology (18309)
- Genetics (12246)
- Genomics (16805)
- Immunology (11870)
- Microbiology (28098)
- Molecular Biology (11598)
- Neuroscience (60979)
- Paleontology (452)
- Pathology (1871)
- Pharmacology and Toxicology (3238)
- Physiology (4960)
- Plant Biology (10427)
- Synthetic Biology (2886)
- Systems Biology (7341)
- Zoology (1651)