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Epilepsy kinase CDKL5 is a DNA damage sensor which controls transcriptional activity at DNA breaks
View ORCID ProfileTaran Khanam, View ORCID ProfileIvan Muñoz, View ORCID ProfileFlorian Weiland, View ORCID ProfileThomas Carroll, View ORCID ProfileBarbara N Borsos, View ORCID ProfileVasiliki Pantazi, View ORCID ProfileMeghan Slean, View ORCID ProfileMiroslav Novak, View ORCID ProfileRachel Toth, View ORCID ProfilePaul Appleton, View ORCID ProfileTibor Pankotai, View ORCID ProfileHoujiang Zhou, View ORCID ProfileJohn Rouse
doi: https://doi.org/10.1101/2020.12.10.419747
Taran Khanam
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
Ivan Muñoz
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
Florian Weiland
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
42, Gebroeders De Smetstraat 1, 9000 Ghent, Belgium
Thomas Carroll
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
Barbara N Borsos
5Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, Tisza Lajos korut 83, University of Szeged, 6722 Szeged, Hungary
Vasiliki Pantazi
5Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, Tisza Lajos korut 83, University of Szeged, 6722 Szeged, Hungary
Meghan Slean
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
6Department of Medical Genetics, Polwarth Building, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
Miroslav Novak
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
7Jacqui Wood Cancer Centre, Ninewells Hospital, University of Dundee, Dundee DD1 1UB, Scotland, UK
Rachel Toth
2MRC Reagents and Services, University of Dundee, Dundee DD1 5EH, Scotland, UK
Paul Appleton
3Dundee Imaging Facility, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland, UK
Tibor Pankotai
5Department of Oral Biology and Experimental Dental Research, Faculty of Dentistry, Tisza Lajos korut 83, University of Szeged, 6722 Szeged, Hungary
Houjiang Zhou
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
John Rouse
1MRC Protein Phosphorylation and Ubiquitylation Unit, University of Dundee, Dundee DD1 5EH, Scotland, UK
Posted December 17, 2020.
Epilepsy kinase CDKL5 is a DNA damage sensor which controls transcriptional activity at DNA breaks
Taran Khanam, Ivan Muñoz, Florian Weiland, Thomas Carroll, Barbara N Borsos, Vasiliki Pantazi, Meghan Slean, Miroslav Novak, Rachel Toth, Paul Appleton, Tibor Pankotai, Houjiang Zhou, John Rouse
bioRxiv 2020.12.10.419747; doi: https://doi.org/10.1101/2020.12.10.419747
Epilepsy kinase CDKL5 is a DNA damage sensor which controls transcriptional activity at DNA breaks
Taran Khanam, Ivan Muñoz, Florian Weiland, Thomas Carroll, Barbara N Borsos, Vasiliki Pantazi, Meghan Slean, Miroslav Novak, Rachel Toth, Paul Appleton, Tibor Pankotai, Houjiang Zhou, John Rouse
bioRxiv 2020.12.10.419747; doi: https://doi.org/10.1101/2020.12.10.419747
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