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Atrx deletion impairs cGAS-STING signaling and increases response to radiation and oncolytic herpesvirus in sarcoma
View ORCID ProfileWarren Floyd, Matthew Pierpoint, Chang Su, Lixia Luo, Katherine Deland, View ORCID ProfileAmy J. Wisdom, Daniel Zhu, Yan Ma, Suzanne Bartholf DeWitt, Nerissa T. Williams, Jason A. Somarelli, David L. Corcoran, William C. Eward, Diana M. Cardona, David G. Kirsch
doi: https://doi.org/10.1101/2021.03.08.434225
Warren Floyd
1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA
Matthew Pierpoint
1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA
Chang Su
1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA
Lixia Luo
2Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708
Katherine Deland
2Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708
Amy J. Wisdom
1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA
Daniel Zhu
1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA
Yan Ma
2Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708
Suzanne Bartholf DeWitt
3Department of Orthopaedics, Duke University Medical Center, Durham, NC 27710
Nerissa T. Williams
2Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708
Jason A. Somarelli
4Department of Medicine, Duke University Medical Center, Durham, NC 27710
5Duke Cancer Institute, Durham, NC, 27708
David L. Corcoran
6Center for Genomic and Computational Biology, Duke University, Durham NC, 27710
William C. Eward
3Department of Orthopaedics, Duke University Medical Center, Durham, NC 27710
Diana M. Cardona
7Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710
David G. Kirsch
1Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, NC, 27708, USA
2Department of Radiation Oncology, Duke University Medical Center, Durham, NC, 27708
5Duke Cancer Institute, Durham, NC, 27708
Posted March 09, 2021.
Atrx deletion impairs cGAS-STING signaling and increases response to radiation and oncolytic herpesvirus in sarcoma
Warren Floyd, Matthew Pierpoint, Chang Su, Lixia Luo, Katherine Deland, Amy J. Wisdom, Daniel Zhu, Yan Ma, Suzanne Bartholf DeWitt, Nerissa T. Williams, Jason A. Somarelli, David L. Corcoran, William C. Eward, Diana M. Cardona, David G. Kirsch
bioRxiv 2021.03.08.434225; doi: https://doi.org/10.1101/2021.03.08.434225
Atrx deletion impairs cGAS-STING signaling and increases response to radiation and oncolytic herpesvirus in sarcoma
Warren Floyd, Matthew Pierpoint, Chang Su, Lixia Luo, Katherine Deland, Amy J. Wisdom, Daniel Zhu, Yan Ma, Suzanne Bartholf DeWitt, Nerissa T. Williams, Jason A. Somarelli, David L. Corcoran, William C. Eward, Diana M. Cardona, David G. Kirsch
bioRxiv 2021.03.08.434225; doi: https://doi.org/10.1101/2021.03.08.434225
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