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A systematic genotype-phenotype map for missense variants in the human intellectual disability-associated gene GDI1
View ORCID ProfileRachel A. Silverstein, Song Sun, Marta Verby, View ORCID ProfileJochen Weile, View ORCID ProfileYingzhou Wu, Marinella Gebbia, Iosifina Fotiadou, Julia Kitaygorodsky, Frederick P. Roth
doi: https://doi.org/10.1101/2021.10.06.463360
Rachel A. Silverstein
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
5Division of Medical Sciences, Harvard Medical School, 260 Longwood Ave, Boston, MA 02115, USA
Song Sun
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
4Department of Computer Science, University of Toronto, Toronto, ON M5S 2E4, Canada
6Analytical Sciences, Sanofi Pasteur, Toronto, ON M2R 3T4, Canada
Marta Verby
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
Jochen Weile
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
4Department of Computer Science, University of Toronto, Toronto, ON M5S 2E4, Canada
Yingzhou Wu
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
4Department of Computer Science, University of Toronto, Toronto, ON M5S 2E4, Canada
Marinella Gebbia
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
Iosifina Fotiadou
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
4Department of Computer Science, University of Toronto, Toronto, ON M5S 2E4, Canada
Julia Kitaygorodsky
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
4Department of Computer Science, University of Toronto, Toronto, ON M5S 2E4, Canada
Frederick P. Roth
1Lunenfeld-Tanenbaum Research Institute, Sinai Health, Toronto, ON M5G 1X5, Canada
2The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada
3Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 3E1, Canada
4Department of Computer Science, University of Toronto, Toronto, ON M5S 2E4, Canada
Posted October 11, 2022.
A systematic genotype-phenotype map for missense variants in the human intellectual disability-associated gene GDI1
Rachel A. Silverstein, Song Sun, Marta Verby, Jochen Weile, Yingzhou Wu, Marinella Gebbia, Iosifina Fotiadou, Julia Kitaygorodsky, Frederick P. Roth
bioRxiv 2021.10.06.463360; doi: https://doi.org/10.1101/2021.10.06.463360
A systematic genotype-phenotype map for missense variants in the human intellectual disability-associated gene GDI1
Rachel A. Silverstein, Song Sun, Marta Verby, Jochen Weile, Yingzhou Wu, Marinella Gebbia, Iosifina Fotiadou, Julia Kitaygorodsky, Frederick P. Roth
bioRxiv 2021.10.06.463360; doi: https://doi.org/10.1101/2021.10.06.463360
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