RT Journal Article
SR Electronic
T1 Disrupted serial dependence suggests deficits in synaptic potentiation in anti-NMDAR encephalitis and schizophrenia
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 830471
DO 10.1101/830471
A1 H. Stein
A1 J. Barbosa
A1 M. Rosa-Justicia
A1 L. Prades
A1 A. Morató
A1 A. Galan
A1 H. Ariño
A1 E. Martinez-Hernandez
A1 J. Castro-Fornieles
A1 J. Dalmau
A1 A. Compte
YR 2019
UL http://biorxiv.org/content/early/2019/11/20/830471.abstract
AB We report markedly reduced working memory-related serial dependence with preserved memory accuracy in anti-NMDAR encephalitis and schizophrenia. We argue that NMDAR-related changes in cortical excitation, while quickly destabilizing persistent neural activity, cannot fully account for a reduction of memory-dependent biases. Rather, our modeling results support a disruption of a memory mechanism operating on a longer timescale, such as short-term potentiation.